IL127044A - Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases - Google Patents
Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseasesInfo
- Publication number
- IL127044A IL127044A IL12704497A IL12704497A IL127044A IL 127044 A IL127044 A IL 127044A IL 12704497 A IL12704497 A IL 12704497A IL 12704497 A IL12704497 A IL 12704497A IL 127044 A IL127044 A IL 127044A
- Authority
- IL
- Israel
- Prior art keywords
- neurodegenertive
- diseases
- preparation
- treatment
- pharmaceutical compositions
- Prior art date
Links
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical class NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001013A IT1282736B1 (it) | 1996-05-21 | 1996-05-21 | Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative |
| PCT/EP1997/002708 WO1997044020A1 (en) | 1996-05-21 | 1997-05-15 | Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL127044A0 IL127044A0 (en) | 1999-09-22 |
| IL127044A true IL127044A (en) | 2001-03-19 |
Family
ID=11374289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12704497A IL127044A (en) | 1996-05-21 | 1997-05-15 | Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6043285A (cs) |
| EP (1) | EP0946162B1 (cs) |
| JP (1) | JP2000510859A (cs) |
| AT (1) | ATE252897T1 (cs) |
| AU (1) | AU723004B2 (cs) |
| CZ (1) | CZ295875B6 (cs) |
| DE (1) | DE69725879T2 (cs) |
| DK (1) | DK0946162T3 (cs) |
| EA (1) | EA003251B1 (cs) |
| ES (1) | ES2208909T3 (cs) |
| HU (1) | HU225536B1 (cs) |
| IL (1) | IL127044A (cs) |
| IT (1) | IT1282736B1 (cs) |
| NZ (1) | NZ333232A (cs) |
| PT (1) | PT946162E (cs) |
| SK (1) | SK284860B6 (cs) |
| TR (1) | TR199802384T2 (cs) |
| WO (1) | WO1997044020A1 (cs) |
| ZA (1) | ZA974387B (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI962356A1 (it) * | 1996-11-13 | 1998-05-13 | Uni Degli Studi Di Brescia D I | Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di |
| DE19911626A1 (de) * | 1999-03-16 | 2000-09-28 | Strathmann Ag & Co | Induktion antiinflammatorisch wirkender Proteine durch Ammoniumionen bzw. Amino-Reste |
| BR9904931A (pt) * | 1999-10-18 | 2001-06-12 | Sergio Teixeira Ferreira | Inibição de amiloidoses |
| US6664297B1 (en) * | 2000-10-18 | 2003-12-16 | Universidade Federal Do Rio De Janeiro | Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol |
| WO2004034963A2 (en) * | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| GB0310300D0 (en) * | 2003-05-06 | 2003-06-11 | Univ Belfast | Nanocomposite drug delivery composition |
| US20090221703A1 (en) * | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
| US20090238763A1 (en) | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
| PL2061749T3 (pl) * | 2006-09-03 | 2018-11-30 | Techfields Biochem Co. Ltd | Dodatnio naładowane, rozpuszczalne w wodzie proleki acetaminofenu i związków pokrewnych o bardzo dużej szybkości przenikania przez skórę |
| PL2170826T3 (pl) | 2007-06-04 | 2022-09-05 | Techfields Inc | Proleki nsaia o bardzo wysokim współczynniku przenikania przez skórę i błony oraz ich nowe zastosowania lecznicze |
| MX2010012648A (es) | 2008-05-20 | 2010-12-14 | Neurogesx Inc | Analogos de acetaminofeno solubles en agua. |
| MX2010012649A (es) | 2008-05-20 | 2010-12-21 | Neurogesx Inc | Profarmacos de carbonato y metodos para usar los mismos. |
| BRPI0922263B1 (pt) | 2008-12-04 | 2021-08-31 | Chongxi Yu | Composição de alta penetração de um fármaco principal, e seus usos |
| KR102443057B1 (ko) | 2012-01-18 | 2022-09-14 | 테크필즈 파마 코., 엘티디. | 폐 병태의 치료를 위한 고침투 전구약물 조성물 및 그의 약제학적 조성물 |
| JP5855599B2 (ja) * | 2013-04-30 | 2016-02-09 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ |
| JP5997658B2 (ja) * | 2013-05-08 | 2016-09-28 | テックフィールズ インコーポレイテッド | 非常に速い皮膚及び膜浸透速度を有するnsaiaプロドラッグ及びその新規医薬使用 |
| JP6165816B2 (ja) * | 2015-10-01 | 2017-07-19 | テックフィールズ バイオケム カンパニー リミテッド | 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ |
| WO2022007578A1 (zh) * | 2020-07-10 | 2022-01-13 | 广州新创忆药物临床研究有限公司 | 治疗阿尔茨海默病的组合及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192753A (en) * | 1991-04-23 | 1993-03-09 | Mcgeer Patrick L | Anti-rheumatoid arthritic drugs in the treatment of dementia |
| US5472983A (en) * | 1994-04-14 | 1995-12-05 | Centaur Pharmaceuticals, Inc. | Benzamide-containing pharmaceutical compositions |
| US5643960A (en) * | 1994-04-15 | 1997-07-01 | Duke University | Method of delaying onset of alzheimer's disease symptoms |
| US5756548A (en) * | 1995-04-03 | 1998-05-26 | Centaur Pharmaceuticals, Inc. | Acetamidobenzamide compounds for neurodegenerative disorders |
-
1996
- 1996-05-21 IT IT96MI001013A patent/IT1282736B1/it active IP Right Grant
-
1997
- 1997-05-15 PT PT97925950T patent/PT946162E/pt unknown
- 1997-05-15 HU HU9904027A patent/HU225536B1/hu not_active IP Right Cessation
- 1997-05-15 AU AU30923/97A patent/AU723004B2/en not_active Ceased
- 1997-05-15 US US09/147,280 patent/US6043285A/en not_active Expired - Fee Related
- 1997-05-15 DK DK97925950T patent/DK0946162T3/da active
- 1997-05-15 SK SK1598-98A patent/SK284860B6/sk not_active IP Right Cessation
- 1997-05-15 CZ CZ19983749A patent/CZ295875B6/cs not_active IP Right Cessation
- 1997-05-15 ES ES97925950T patent/ES2208909T3/es not_active Expired - Lifetime
- 1997-05-15 JP JP09541586A patent/JP2000510859A/ja active Pending
- 1997-05-15 DE DE69725879T patent/DE69725879T2/de not_active Expired - Fee Related
- 1997-05-15 EP EP97925950A patent/EP0946162B1/en not_active Expired - Lifetime
- 1997-05-15 WO PCT/EP1997/002708 patent/WO1997044020A1/en active IP Right Grant
- 1997-05-15 EA EA199801028A patent/EA003251B1/ru not_active IP Right Cessation
- 1997-05-15 AT AT97925950T patent/ATE252897T1/de not_active IP Right Cessation
- 1997-05-15 NZ NZ333232A patent/NZ333232A/xx unknown
- 1997-05-15 TR TR1998/02384T patent/TR199802384T2/xx unknown
- 1997-05-15 IL IL12704497A patent/IL127044A/xx not_active IP Right Cessation
- 1997-05-20 ZA ZA9704387A patent/ZA974387B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA199801028A1 (ru) | 1999-06-24 |
| EP0946162A1 (en) | 1999-10-06 |
| EP0946162B1 (en) | 2003-10-29 |
| CZ374998A3 (cs) | 1999-04-14 |
| ITMI961013A1 (it) | 1997-11-21 |
| ES2208909T3 (es) | 2004-06-16 |
| CZ295875B6 (cs) | 2005-11-16 |
| DE69725879T2 (de) | 2004-09-02 |
| HUP9904027A2 (hu) | 2000-05-28 |
| IL127044A0 (en) | 1999-09-22 |
| ATE252897T1 (de) | 2003-11-15 |
| HUP9904027A3 (en) | 2000-07-28 |
| WO1997044020A1 (en) | 1997-11-27 |
| JP2000510859A (ja) | 2000-08-22 |
| SK284860B6 (sk) | 2006-01-05 |
| EA003251B1 (ru) | 2003-02-27 |
| SK159898A3 (en) | 2000-04-10 |
| DK0946162T3 (da) | 2004-03-01 |
| HU225536B1 (en) | 2007-02-28 |
| IT1282736B1 (it) | 1998-03-31 |
| PT946162E (pt) | 2004-03-31 |
| NZ333232A (en) | 2000-08-25 |
| ZA974387B (en) | 1997-12-23 |
| ITMI961013A0 (cs) | 1996-05-21 |
| AU3092397A (en) | 1997-12-09 |
| US6043285A (en) | 2000-03-28 |
| TR199802384T2 (xx) | 1999-03-22 |
| AU723004B2 (en) | 2000-08-17 |
| DE69725879D1 (de) | 2003-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |