ATE252897T1 - Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen - Google Patents

Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen

Info

Publication number
ATE252897T1
ATE252897T1 AT97925950T AT97925950T ATE252897T1 AT E252897 T1 ATE252897 T1 AT E252897T1 AT 97925950 T AT97925950 T AT 97925950T AT 97925950 T AT97925950 T AT 97925950T AT E252897 T1 ATE252897 T1 AT E252897T1
Authority
AT
Austria
Prior art keywords
treatment
production
pharmaceutical compositions
neurodegenerative diseases
pct
Prior art date
Application number
AT97925950T
Other languages
English (en)
Inventor
Mario Pinza
Mario Brufani
Claudio Milanese
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of ATE252897T1 publication Critical patent/ATE252897T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97925950T 1996-05-21 1997-05-15 Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen ATE252897T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001013A IT1282736B1 (it) 1996-05-21 1996-05-21 Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative
PCT/EP1997/002708 WO1997044020A1 (en) 1996-05-21 1997-05-15 Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases

Publications (1)

Publication Number Publication Date
ATE252897T1 true ATE252897T1 (de) 2003-11-15

Family

ID=11374289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97925950T ATE252897T1 (de) 1996-05-21 1997-05-15 Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen

Country Status (19)

Country Link
US (1) US6043285A (de)
EP (1) EP0946162B1 (de)
JP (1) JP2000510859A (de)
AT (1) ATE252897T1 (de)
AU (1) AU723004B2 (de)
CZ (1) CZ295875B6 (de)
DE (1) DE69725879T2 (de)
DK (1) DK0946162T3 (de)
EA (1) EA003251B1 (de)
ES (1) ES2208909T3 (de)
HU (1) HU225536B1 (de)
IL (1) IL127044A (de)
IT (1) IT1282736B1 (de)
NZ (1) NZ333232A (de)
PT (1) PT946162E (de)
SK (1) SK284860B6 (de)
TR (1) TR199802384T2 (de)
WO (1) WO1997044020A1 (de)
ZA (1) ZA974387B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI962356A1 (it) * 1996-11-13 1998-05-13 Uni Degli Studi Di Brescia D I Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di
DE19911626A1 (de) * 1999-03-16 2000-09-28 Strathmann Ag & Co Induktion antiinflammatorisch wirkender Proteine durch Ammoniumionen bzw. Amino-Reste
BR9904931A (pt) * 1999-10-18 2001-06-12 Sergio Teixeira Ferreira Inibição de amiloidoses
US6664297B1 (en) * 2000-10-18 2003-12-16 Universidade Federal Do Rio De Janeiro Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol
WO2004034963A2 (en) * 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
GB0310300D0 (en) * 2003-05-06 2003-06-11 Univ Belfast Nanocomposite drug delivery composition
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) * 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
CA2661649C (en) * 2006-09-03 2014-12-30 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of acetaminophen and related compounds with very fast skin penetration rate
KR20210103586A (ko) * 2007-06-04 2021-08-23 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도
KR101677126B1 (ko) 2008-05-20 2016-11-22 노이로제스엑스, 인코포레이티드 탄산염 프로드러그 및 그것의 사용 방법
CA2724877C (en) 2008-05-20 2016-09-13 Neurogesx, Inc. Water-soluble acetaminophen analogs
RU2630577C2 (ru) 2008-12-04 2017-09-11 Чунси ЮЙ Композиции интенсивного проникновения и их применение
CN116898848A (zh) 2012-01-18 2023-10-20 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
JP5855599B2 (ja) * 2013-04-30 2016-02-09 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
JP5997658B2 (ja) * 2013-05-08 2016-09-28 テックフィールズ インコーポレイテッド 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用
JP6165816B2 (ja) * 2015-10-01 2017-07-19 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
WO2022007578A1 (zh) * 2020-07-10 2022-01-13 广州新创忆药物临床研究有限公司 治疗阿尔茨海默病的组合及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192753A (en) * 1991-04-23 1993-03-09 Mcgeer Patrick L Anti-rheumatoid arthritic drugs in the treatment of dementia
US5472983A (en) * 1994-04-14 1995-12-05 Centaur Pharmaceuticals, Inc. Benzamide-containing pharmaceutical compositions
US5643960A (en) * 1994-04-15 1997-07-01 Duke University Method of delaying onset of alzheimer's disease symptoms
US5756548A (en) * 1995-04-03 1998-05-26 Centaur Pharmaceuticals, Inc. Acetamidobenzamide compounds for neurodegenerative disorders

Also Published As

Publication number Publication date
WO1997044020A1 (en) 1997-11-27
IT1282736B1 (it) 1998-03-31
HU225536B1 (en) 2007-02-28
JP2000510859A (ja) 2000-08-22
SK159898A3 (en) 2000-04-10
DE69725879D1 (de) 2003-12-04
IL127044A0 (en) 1999-09-22
ES2208909T3 (es) 2004-06-16
AU3092397A (en) 1997-12-09
AU723004B2 (en) 2000-08-17
US6043285A (en) 2000-03-28
ITMI961013A0 (de) 1996-05-21
CZ295875B6 (cs) 2005-11-16
EA199801028A1 (ru) 1999-06-24
HUP9904027A3 (en) 2000-07-28
EP0946162A1 (de) 1999-10-06
IL127044A (en) 2001-03-19
HUP9904027A2 (hu) 2000-05-28
DK0946162T3 (da) 2004-03-01
ZA974387B (en) 1997-12-23
PT946162E (pt) 2004-03-31
EA003251B1 (ru) 2003-02-27
EP0946162B1 (de) 2003-10-29
TR199802384T2 (xx) 1999-03-22
CZ374998A3 (cs) 1999-04-14
ITMI961013A1 (it) 1997-11-21
NZ333232A (en) 2000-08-25
DE69725879T2 (de) 2004-09-02
SK284860B6 (sk) 2006-01-05

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