IL122774A0 - Neurturin and related growth factors - Google Patents
Neurturin and related growth factorsInfo
- Publication number
- IL122774A0 IL122774A0 IL12277496A IL12277496A IL122774A0 IL 122774 A0 IL122774 A0 IL 122774A0 IL 12277496 A IL12277496 A IL 12277496A IL 12277496 A IL12277496 A IL 12277496A IL 122774 A0 IL122774 A0 IL 122774A0
- Authority
- IL
- Israel
- Prior art keywords
- neurturin
- methods
- growth factors
- vectors
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/519,777 US5739307A (en) | 1995-08-28 | 1995-08-28 | Polynucleotide encoding neurturin neurotrophic factor |
PCT/US1996/014065 WO1997008196A1 (en) | 1995-08-28 | 1996-08-27 | Neurturin and related growth factors |
Publications (1)
Publication Number | Publication Date |
---|---|
IL122774A0 true IL122774A0 (en) | 1998-08-16 |
Family
ID=24069730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12277496A IL122774A0 (en) | 1995-08-28 | 1996-08-27 | Neurturin and related growth factors |
Country Status (12)
Country | Link |
---|---|
US (6) | US5739307A (ja) |
EP (1) | EP0787142B1 (ja) |
JP (1) | JP4222629B2 (ja) |
AT (1) | ATE315578T1 (ja) |
AU (1) | AU714107B2 (ja) |
CA (1) | CA2194172C (ja) |
DE (1) | DE69635738T2 (ja) |
DK (1) | DK0787142T3 (ja) |
IL (1) | IL122774A0 (ja) |
MX (1) | MX9800277A (ja) |
NZ (3) | NZ318939A (ja) |
WO (1) | WO1997008196A1 (ja) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743628B1 (en) * | 1995-08-28 | 2004-06-01 | Washington University | Method of cell culture using neurturin |
US6184200B1 (en) | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US6222022B1 (en) | 1996-03-14 | 2001-04-24 | Washington University | Persephin and related growth factors |
DE69732350T2 (de) | 1996-03-14 | 2005-12-22 | Washington University | Persephin und verwandte wachstumsfaktoren |
US7015316B1 (en) * | 1996-03-14 | 2006-03-21 | Washington University | Polynucleotides encoding human persephin and related growth factors |
BR9713055A (pt) | 1996-11-15 | 2000-04-04 | Genentech Inc | Processo para isolar uma neurotrofina humana recombinante, composição de neurotrofina e processo para purificar uma neurotrofina |
NZ501423A (en) * | 1997-04-17 | 2002-02-01 | Univ Washington | Receptors for TGF-beta-related neurotrophic factors and use for treating disease |
US7723473B2 (en) * | 1997-06-19 | 2010-05-25 | St. Louis University | Peptide antagonists of TGF-beta family members and therapeutic uses thereof |
US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
SI1005358T1 (en) * | 1997-07-30 | 2003-06-30 | Amgen Inc. | Use of a neurturin protein product for preventing and treating hearing loss |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
KR100773776B1 (ko) * | 1998-07-14 | 2007-11-12 | 얀센 파마슈티카 엔.브이. | 신경친화성 성장 인자 |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
US6268352B1 (en) * | 1998-09-02 | 2001-07-31 | The Regents Of The University Of California | Promoters of neural regeneration |
US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
ATE406907T1 (de) * | 1998-10-28 | 2008-09-15 | Cornell Res Foundation Inc | Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4 |
ES2246234T3 (es) | 1999-05-04 | 2006-02-16 | Strakan International Limited | Glicosidos de androgenos y actividad androgenica de los mismos. |
EP1179067B1 (en) * | 1999-05-17 | 2006-12-13 | BIOPHARM Gesellschaft zur biotechnologischen Entwicklung und zum Vertrieb von Pharmaka mbH | Neuroprotective properties of gdf-15, a member of the tgf-beta superfamily |
DE60045045D1 (de) * | 1999-11-05 | 2010-11-11 | Hexima Ltd | Nukleinsäuremoleküle zur kodierung cyclisierbare aminosäuresequenzen |
US6866851B1 (en) | 1999-12-28 | 2005-03-15 | Washington University | GFRα1-RET specific agonists and methods therefor |
GB0024550D0 (ja) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
AU2002250203B2 (en) | 2001-03-28 | 2006-08-10 | Biogen Ma Inc. | Use of neublastin polypeptides for treating neuropathic pain |
US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
US20050222070A1 (en) * | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
AU2003238178A1 (en) | 2002-05-29 | 2003-12-12 | Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung | Pancreas-specific proteins |
CN100567987C (zh) * | 2002-08-08 | 2009-12-09 | 贝勒医学院 | T细胞疫苗及其制备方法 |
EP1897552B1 (en) | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymer-conjugated glycosylated neublastin |
US20040229269A1 (en) * | 2003-05-15 | 2004-11-18 | Ghazala Hashmi | Hybridization-mediated analysis of polymorphisms |
ATE478092T1 (de) | 2003-06-10 | 2010-09-15 | Nsgene As | Verbesserte sekretion von neublastin |
WO2005026382A1 (en) * | 2003-09-12 | 2005-03-24 | Stemcell Technologies Inc. | Neural colony forming assay |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
RU2006117304A (ru) | 2003-10-20 | 2007-12-10 | Нсджин А/С (Dk) | Генная терапия болезни паркинсона iv vivo |
EP1694354B1 (en) | 2003-11-27 | 2009-07-01 | DeveloGen Aktiengesellschaft | Method for preventing and treating diabetes using neurturin |
AU2005277227B2 (en) | 2004-08-19 | 2011-10-06 | Biogen Ma Inc. | Refolding transforming growth factor beta family proteins |
MX2007002029A (es) | 2004-08-19 | 2007-03-28 | Biogen Idec Inc | Variantes de neublastina. |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
DK2016414T3 (en) * | 2006-05-05 | 2015-12-07 | Opexa Therapeutics | T-cell vaccine |
EP1872790A1 (en) | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | New formulation for increasing bioavailability of neurturin |
CA2685686A1 (en) | 2007-05-01 | 2008-11-13 | Biogen Idec Ma Inc. | Neublastin polypeptides for use increasing vascularization in a tissue |
US8946201B2 (en) | 2007-08-27 | 2015-02-03 | Saint Louis University | Methods for inhibiting TGF-β |
EA201070484A1 (ru) | 2007-11-05 | 2011-04-29 | Девелоген Акциенгезельшафт | Новые конъюгаты нейртурина для фармацевтического применения |
CN102159219B (zh) | 2008-09-16 | 2015-06-24 | 圣路易斯大学 | 提高转化生长因子-β信号发送的方法 |
US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
JP2013509422A (ja) * | 2009-10-30 | 2013-03-14 | シーエヌエス セラピューティクス,インク. | 改良されたニュールツリン分子 |
US8564522B2 (en) * | 2010-03-31 | 2013-10-22 | Apple Inc. | Reduced-power communications within an electronic display |
EP2394665A1 (en) * | 2010-06-14 | 2011-12-14 | F. Hoffmann-La Roche AG | Cell-penetrating peptides and uses therof |
WO2011157713A2 (en) | 2010-06-14 | 2011-12-22 | F. Hoffmann-La Roche Ag | Cell-penetrating peptides and uses therof |
US9869272B1 (en) | 2011-04-20 | 2018-01-16 | Martin A. Stuart | Performance of a transcritical or supercritical CO2 Rankin cycle engine |
EP2594295A1 (en) | 2011-11-16 | 2013-05-22 | Servicio Andaluz De Salud | Nerve implants based on a compacted biomaterial containing cells |
JP2019502674A (ja) * | 2015-08-25 | 2019-01-31 | ヒスタイド アクツィエンゲゼルシャフト | 組織形成誘導用化合物及びその使用 |
KR20180043317A (ko) | 2015-08-25 | 2018-04-27 | 히스티드 아게 | 조직 형성 유도용 화합물 및 그것의 용도 |
EA038283B1 (ru) * | 2016-04-13 | 2021-08-04 | Юниверситейт Маастрихт | Способ лечения или предупреждения остеоартрита |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5011914A (en) * | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
US5141856A (en) * | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
EP0592675A1 (en) | 1991-06-29 | 1994-04-20 | Kao Corporation | Method of forming fixed images |
HU220795B1 (hu) * | 1991-09-20 | 2002-05-28 | Amgen Inc. | Gliasejtvonal-eredetű neurotróf faktorfehérjék, továbbá berendezések és gyógyászati készítmények idegsejtkárosodás megelőzésére és kezelésére |
EP0721464A4 (en) * | 1993-09-01 | 1998-12-30 | Start Technology Partnership | NEURON REGULATOR FACTOR FOR PROMOTING NEURON SURVIVAL |
AU1443095A (en) * | 1993-12-22 | 1995-07-10 | University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
DE69732350T2 (de) * | 1996-03-14 | 2005-12-22 | Washington University | Persephin und verwandte wachstumsfaktoren |
-
1995
- 1995-08-28 US US08/519,777 patent/US5739307A/en not_active Expired - Lifetime
-
1996
- 1996-08-27 DE DE69635738T patent/DE69635738T2/de not_active Expired - Lifetime
- 1996-08-27 JP JP51062897A patent/JP4222629B2/ja not_active Expired - Lifetime
- 1996-08-27 WO PCT/US1996/014065 patent/WO1997008196A1/en active IP Right Grant
- 1996-08-27 NZ NZ318939A patent/NZ318939A/xx not_active IP Right Cessation
- 1996-08-27 IL IL12277496A patent/IL122774A0/xx not_active IP Right Cessation
- 1996-08-27 CA CA2194172A patent/CA2194172C/en not_active Expired - Lifetime
- 1996-08-27 NZ NZ332921A patent/NZ332921A/en not_active IP Right Cessation
- 1996-08-27 EP EP96932163A patent/EP0787142B1/en not_active Expired - Lifetime
- 1996-08-27 DK DK96932163T patent/DK0787142T3/da active
- 1996-08-27 AT AT96932163T patent/ATE315578T1/de not_active IP Right Cessation
- 1996-08-27 NZ NZ332922A patent/NZ332922A/xx not_active IP Right Cessation
- 1996-08-27 AU AU71054/96A patent/AU714107B2/en not_active Expired
- 1996-11-01 US US08/742,035 patent/US5747655A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,019 patent/US5817622A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,143 patent/US5843914A/en not_active Expired - Lifetime
- 1996-12-31 US US08/775,414 patent/US6090778A/en not_active Expired - Lifetime
-
1998
- 1998-01-07 MX MX9800277A patent/MX9800277A/es unknown
-
1999
- 1999-12-30 US US09/476,290 patent/US7015311B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK0787142T3 (da) | 2006-05-29 |
US7015311B1 (en) | 2006-03-21 |
JPH11512928A (ja) | 1999-11-09 |
US5747655A (en) | 1998-05-05 |
CA2194172A1 (en) | 1997-03-01 |
CA2194172C (en) | 2012-07-10 |
US6090778A (en) | 2000-07-18 |
US5817622A (en) | 1998-10-06 |
ATE315578T1 (de) | 2006-02-15 |
EP0787142A1 (en) | 1997-08-06 |
US5843914A (en) | 1998-12-01 |
NZ332921A (en) | 2001-03-30 |
JP4222629B2 (ja) | 2009-02-12 |
AU714107B2 (en) | 1999-12-16 |
MX9800277A (es) | 1998-09-30 |
EP0787142A4 (en) | 1999-04-07 |
DE69635738D1 (de) | 2006-04-06 |
AU7105496A (en) | 1997-03-19 |
NZ318939A (en) | 1999-01-28 |
EP0787142B1 (en) | 2006-01-11 |
NZ332922A (en) | 1999-07-29 |
DE69635738T2 (de) | 2006-08-31 |
WO1997008196A1 (en) | 1997-03-06 |
US5739307A (en) | 1998-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |