DE69635738D1 - Neuriturin und verwandte wachstumsfaktoren - Google Patents
Neuriturin und verwandte wachstumsfaktorenInfo
- Publication number
- DE69635738D1 DE69635738D1 DE69635738T DE69635738T DE69635738D1 DE 69635738 D1 DE69635738 D1 DE 69635738D1 DE 69635738 T DE69635738 T DE 69635738T DE 69635738 T DE69635738 T DE 69635738T DE 69635738 D1 DE69635738 D1 DE 69635738D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- neurturin
- growth factors
- vectors
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US519777 | 1995-08-28 | ||
US08/519,777 US5739307A (en) | 1995-08-28 | 1995-08-28 | Polynucleotide encoding neurturin neurotrophic factor |
PCT/US1996/014065 WO1997008196A1 (en) | 1995-08-28 | 1996-08-27 | Neurturin and related growth factors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69635738D1 true DE69635738D1 (de) | 2006-04-06 |
DE69635738T2 DE69635738T2 (de) | 2006-08-31 |
Family
ID=24069730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69635738T Expired - Lifetime DE69635738T2 (de) | 1995-08-28 | 1996-08-27 | Neurturin und verwandte Wachstumsfaktoren |
Country Status (12)
Country | Link |
---|---|
US (6) | US5739307A (de) |
EP (1) | EP0787142B1 (de) |
JP (1) | JP4222629B2 (de) |
AT (1) | ATE315578T1 (de) |
AU (1) | AU714107B2 (de) |
CA (1) | CA2194172C (de) |
DE (1) | DE69635738T2 (de) |
DK (1) | DK0787142T3 (de) |
IL (1) | IL122774A0 (de) |
MX (1) | MX9800277A (de) |
NZ (3) | NZ332922A (de) |
WO (1) | WO1997008196A1 (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743628B1 (en) * | 1995-08-28 | 2004-06-01 | Washington University | Method of cell culture using neurturin |
US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US6222022B1 (en) | 1996-03-14 | 2001-04-24 | Washington University | Persephin and related growth factors |
EP0886651B1 (de) | 1996-03-14 | 2005-01-26 | Washington University | Persephin und verwandte wachstumsfaktoren |
US7015316B1 (en) | 1996-03-14 | 2006-03-21 | Washington University | Polynucleotides encoding human persephin and related growth factors |
CZ300296B6 (cs) * | 1996-11-15 | 2009-04-15 | Genentech, Inc. | Zpusob izolace rekombinantního lidského neurotrofinu, neurotrofinový prostredek a zpusob cištení neurotrofinu |
NZ501423A (en) * | 1997-04-17 | 2002-02-01 | Univ Washington | Receptors for TGF-beta-related neurotrophic factors and use for treating disease |
US7723473B2 (en) * | 1997-06-19 | 2010-05-25 | St. Louis University | Peptide antagonists of TGF-beta family members and therapeutic uses thereof |
US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
EP1304119A3 (de) * | 1997-07-30 | 2004-01-21 | Amgen Inc. | Verfahren zur Vorbeugung und Behandlung von Gehörverlust mit Neurturin Protein |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
DK1640381T3 (da) * | 1998-07-14 | 2014-07-14 | Janssen Pharmaceutica Nv | Neurotrofisk vækstfaktor |
US7067473B1 (en) | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
US6268352B1 (en) * | 1998-09-02 | 2001-07-31 | The Regents Of The University Of California | Promoters of neural regeneration |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
DE69939484D1 (de) * | 1998-10-28 | 2008-10-16 | Cornell Res Foundation Inc | Methoden zur regulierung der angiogenese und vaskuläre integrität mittels trk rezeptor liganden bdnf, nt-3 und nt-4 |
HUP0200871A3 (en) | 1999-05-04 | 2004-04-28 | Strakan Int Ltd | Androgen glycosides and androgenic activity thereof |
CA2372119A1 (en) * | 1999-05-17 | 2000-11-23 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrie B Von Pharmaka Mbh | Neuroprotective properties of gdf-15, a novel member of the tgf-.beta. superfamily |
JP2003527834A (ja) * | 1999-11-05 | 2003-09-24 | ザ・ユニバーシティ・オブ・クイーンズランド | 新規な核酸分子 |
US6866851B1 (en) | 1999-12-28 | 2005-03-15 | Washington University | GFRα1-RET specific agonists and methods therefor |
GB0024550D0 (de) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
JP4499362B2 (ja) | 2001-03-28 | 2010-07-07 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | ニューロパシーの疼痛を処置するためのニューブラスチンポリペプチドの使用 |
US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
US20050222070A1 (en) * | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
EP2269628A3 (de) | 2002-05-29 | 2011-04-20 | DeveloGen Aktiengesellschaft | Pankreas spezifische proteine |
KR100795840B1 (ko) * | 2002-08-08 | 2008-01-17 | 베일러 칼리지 오브 메디신 | T세포의 분리 및 식별 |
CA2864810A1 (en) | 2003-04-18 | 2004-11-04 | Biogen Idec Ma, Inc. | Polymer-conjugated glycosylated neublastin |
US20040229269A1 (en) * | 2003-05-15 | 2004-11-18 | Ghazala Hashmi | Hybridization-mediated analysis of polymorphisms |
ES2353457T3 (es) | 2003-06-10 | 2011-03-02 | Nsgene A/S | Secreción mejorada de neublastina. |
ATE493504T1 (de) * | 2003-09-12 | 2011-01-15 | Stemcell Technologies Inc | Test für neurale koloniebildung |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
JP2007509109A (ja) | 2003-10-20 | 2007-04-12 | エヌエスジーン・アクティーゼルスカブ | パーキンソン病のインビボ遺伝子治療 |
PL1694354T3 (pl) | 2003-11-27 | 2009-12-31 | Develogen Ag | Sposób zapobiegania i leczenia cukrzycy za pomocą neurturyny |
EP2238983B1 (de) | 2004-08-19 | 2014-07-23 | Biogen Idec MA Inc. | Neublastinvarianten |
NZ553420A (en) | 2004-08-19 | 2010-02-26 | Biogen Idec Inc | Refolding transforming growth factor beta family proteins |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
US20100003228A1 (en) * | 2006-05-05 | 2010-01-07 | Willimas Jim C | T-cell vaccine |
EP1872790A1 (de) | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | Neue Zusammensetzung zur Erhöhung der Bioverfügbarkeit von Neurturin |
US8329655B2 (en) | 2007-05-01 | 2012-12-11 | Biogen Idec Ma Inc. | Methods for increasing vascularization |
US8946201B2 (en) | 2007-08-27 | 2015-02-03 | Saint Louis University | Methods for inhibiting TGF-β |
BRPI0819220A2 (pt) | 2007-11-05 | 2019-02-26 | Develogen Aktiengessellschaft | proteína neurturina ou fragmento da mesma, sua composição farmacêutica e uso |
WO2010033507A1 (en) | 2008-09-16 | 2010-03-25 | St. Louis University | Method of enhancing tgf-beta signalling |
US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
AU2010313456A1 (en) * | 2009-10-30 | 2012-05-17 | Ntf Therapeutics, Inc. | Improved neurturin molecules |
US8564522B2 (en) * | 2010-03-31 | 2013-10-22 | Apple Inc. | Reduced-power communications within an electronic display |
NZ704191A (en) * | 2010-06-14 | 2016-05-27 | Hoffmann La Roche | Cell-penetrating peptides and uses therof |
EP2394665A1 (de) * | 2010-06-14 | 2011-12-14 | F. Hoffmann-La Roche AG | Zellenpenetrierende Peptide und Verwendungen davon |
US9869272B1 (en) | 2011-04-20 | 2018-01-16 | Martin A. Stuart | Performance of a transcritical or supercritical CO2 Rankin cycle engine |
EP2594295A1 (de) | 2011-11-16 | 2013-05-22 | Servicio Andaluz De Salud | Nervenimplantat basierend auf einem kompaktierten, zellhaltigen Biomaterial |
EP3341397A2 (de) * | 2015-08-25 | 2018-07-04 | Histide AG | Verbindungen zur induzierung von gewebebildung und verwendungen davon |
CA2995310A1 (en) | 2015-08-25 | 2017-03-02 | Histide Ag | Compounds for inducing tissue formation and uses thereof |
EP3442559B1 (de) * | 2016-04-13 | 2024-05-01 | Chondropeptix B.V. | Bmp-7 abgeleitete peptide zur verwendung in der behandlung oder prevention von osteoarthritis |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5011914A (en) * | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
US5141856A (en) * | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
EP0592675A1 (de) | 1991-06-29 | 1994-04-20 | Kao Corporation | Verfahren zum erzeugen von fixierten bildern |
EP1243652A3 (de) * | 1991-09-20 | 2003-03-26 | Amgen Inc., | Glial neurotropher Faktor |
CA2170751A1 (en) * | 1993-09-01 | 1995-03-09 | Timothy J. Cunningham | Neuron regulatory factor for promoting neuron survival |
WO1995017203A1 (en) * | 1993-12-22 | 1995-06-29 | The University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
EP0886651B1 (de) * | 1996-03-14 | 2005-01-26 | Washington University | Persephin und verwandte wachstumsfaktoren |
-
1995
- 1995-08-28 US US08/519,777 patent/US5739307A/en not_active Expired - Lifetime
-
1996
- 1996-08-27 NZ NZ332922A patent/NZ332922A/xx not_active IP Right Cessation
- 1996-08-27 NZ NZ332921A patent/NZ332921A/en not_active IP Right Cessation
- 1996-08-27 WO PCT/US1996/014065 patent/WO1997008196A1/en active IP Right Grant
- 1996-08-27 CA CA2194172A patent/CA2194172C/en not_active Expired - Lifetime
- 1996-08-27 EP EP96932163A patent/EP0787142B1/de not_active Expired - Lifetime
- 1996-08-27 AU AU71054/96A patent/AU714107B2/en not_active Expired
- 1996-08-27 NZ NZ318939A patent/NZ318939A/xx not_active IP Right Cessation
- 1996-08-27 JP JP51062897A patent/JP4222629B2/ja not_active Expired - Lifetime
- 1996-08-27 AT AT96932163T patent/ATE315578T1/de not_active IP Right Cessation
- 1996-08-27 IL IL12277496A patent/IL122774A0/xx not_active IP Right Cessation
- 1996-08-27 DK DK96932163T patent/DK0787142T3/da active
- 1996-08-27 DE DE69635738T patent/DE69635738T2/de not_active Expired - Lifetime
- 1996-11-01 US US08/742,035 patent/US5747655A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,019 patent/US5817622A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,143 patent/US5843914A/en not_active Expired - Lifetime
- 1996-12-31 US US08/775,414 patent/US6090778A/en not_active Expired - Lifetime
-
1998
- 1998-01-07 MX MX9800277A patent/MX9800277A/es unknown
-
1999
- 1999-12-30 US US09/476,290 patent/US7015311B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5843914A (en) | 1998-12-01 |
US5817622A (en) | 1998-10-06 |
MX9800277A (es) | 1998-09-30 |
AU7105496A (en) | 1997-03-19 |
ATE315578T1 (de) | 2006-02-15 |
DK0787142T3 (da) | 2006-05-29 |
US5747655A (en) | 1998-05-05 |
DE69635738T2 (de) | 2006-08-31 |
US7015311B1 (en) | 2006-03-21 |
CA2194172C (en) | 2012-07-10 |
EP0787142A1 (de) | 1997-08-06 |
NZ332922A (en) | 1999-07-29 |
JP4222629B2 (ja) | 2009-02-12 |
AU714107B2 (en) | 1999-12-16 |
WO1997008196A1 (en) | 1997-03-06 |
EP0787142A4 (de) | 1999-04-07 |
CA2194172A1 (en) | 1997-03-01 |
NZ332921A (en) | 2001-03-30 |
JPH11512928A (ja) | 1999-11-09 |
US5739307A (en) | 1998-04-14 |
US6090778A (en) | 2000-07-18 |
NZ318939A (en) | 1999-01-28 |
EP0787142B1 (de) | 2006-01-11 |
IL122774A0 (en) | 1998-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |