DK0787142T3 - Neurturin og beslægtede vækstfaktorer - Google Patents
Neurturin og beslægtede vækstfaktorerInfo
- Publication number
- DK0787142T3 DK0787142T3 DK96932163T DK96932163T DK0787142T3 DK 0787142 T3 DK0787142 T3 DK 0787142T3 DK 96932163 T DK96932163 T DK 96932163T DK 96932163 T DK96932163 T DK 96932163T DK 0787142 T3 DK0787142 T3 DK 0787142T3
- Authority
- DK
- Denmark
- Prior art keywords
- neurturin
- methods
- growth factors
- vectors
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/519,777 US5739307A (en) | 1995-08-28 | 1995-08-28 | Polynucleotide encoding neurturin neurotrophic factor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0787142T3 true DK0787142T3 (da) | 2006-05-29 |
Family
ID=24069730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96932163T DK0787142T3 (da) | 1995-08-28 | 1996-08-27 | Neurturin og beslægtede vækstfaktorer |
Country Status (12)
Country | Link |
---|---|
US (6) | US5739307A (da) |
EP (1) | EP0787142B1 (da) |
JP (1) | JP4222629B2 (da) |
AT (1) | ATE315578T1 (da) |
AU (1) | AU714107B2 (da) |
CA (1) | CA2194172C (da) |
DE (1) | DE69635738T2 (da) |
DK (1) | DK0787142T3 (da) |
IL (1) | IL122774A0 (da) |
MX (1) | MX9800277A (da) |
NZ (3) | NZ332921A (da) |
WO (1) | WO1997008196A1 (da) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743628B1 (en) * | 1995-08-28 | 2004-06-01 | Washington University | Method of cell culture using neurturin |
US6184200B1 (en) | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US6716600B1 (en) | 1996-03-14 | 2004-04-06 | Washington University | Persephin and related growth factors |
AU716846B2 (en) | 1996-03-14 | 2000-03-09 | Washington University | Persephin and related growth factors |
US6222022B1 (en) | 1996-03-14 | 2001-04-24 | Washington University | Persephin and related growth factors |
IL129851A0 (en) | 1996-11-15 | 2000-02-29 | Genentech Inc | Purification of neurotrophins |
WO1998046622A1 (en) * | 1997-04-17 | 1998-10-22 | Washington University | RECEPTORS FOR TGF-β-RELATED NEUROTROPHIC FACTORS |
US7723473B2 (en) * | 1997-06-19 | 2010-05-25 | St. Louis University | Peptide antagonists of TGF-beta family members and therapeutic uses thereof |
SI1005358T1 (en) * | 1997-07-30 | 2003-06-30 | Amgen Inc. | Use of a neurturin protein product for preventing and treating hearing loss |
US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
JP4469500B2 (ja) * | 1998-07-14 | 2010-05-26 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 神経栄養成長因子 |
US6268352B1 (en) * | 1998-09-02 | 2001-07-31 | The Regents Of The University Of California | Promoters of neural regeneration |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
WO2000024415A2 (en) * | 1998-10-28 | 2000-05-04 | Cornell Research Foundation, Inc. | Methods for regulating angiogenesis and vascular integrity using trk receptor ligands |
PT1175433E (pt) | 1999-05-04 | 2005-11-30 | Strakan Int Ltd | Glicosidos androgenos e sua actividade androgenica |
JP2002543841A (ja) * | 1999-05-17 | 2002-12-24 | バイオファーム ゲゼルシャフト ツア バイオテクノロジシェン エントヴィックルング ウント ツム フェルトリーブ フォン ファルマカ エムベーハー | TGF−βスーパーファミリーの新規のメンバーであるGDF―15の神経保護特性 |
US7592433B1 (en) * | 1999-11-05 | 2009-09-22 | The University Of Queensland; Hexima Limited | Polynucleotides encoding cyclotide-like structures |
US6866851B1 (en) | 1999-12-28 | 2005-03-15 | Washington University | GFRα1-RET specific agonists and methods therefor |
GB0024550D0 (da) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
WO2002078730A2 (en) | 2001-03-28 | 2002-10-10 | Biogen, Inc. | Use of neublastin polypeptides for treating neuropathic pain |
US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
WO2003099318A2 (en) | 2002-05-29 | 2003-12-04 | DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung | Pancreas-specific proteins |
US20050222070A1 (en) * | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
EP2363710B1 (en) * | 2002-08-08 | 2015-07-01 | Baylor College Of Medicine | Isolation and identification of T cells |
WO2004094592A2 (en) | 2003-04-18 | 2004-11-04 | Biogen Idec Ma Inc. | Polymer-conjugated glycosylated neublastin |
WO2004104172A2 (en) * | 2003-05-15 | 2004-12-02 | Bioarray Solutions, Ltd. | Hybridization-mediated analysis of polymorphisms |
AU2004245175C1 (en) | 2003-06-10 | 2010-03-18 | Biogen Ma Inc. | Improved secretion of neublastin |
CN1867678B (zh) * | 2003-09-12 | 2012-10-03 | 干细胞技术公司 | 神经集落形成分析 |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
BRPI0415563A (pt) | 2003-10-20 | 2007-01-02 | Nsgene As | método para o tratamento do mal de parkinson, uso de um vetor viral, vetor de expressão viral, composição farmacêutica, célula hospedeira isolada, linhagem de células de empacotamento, mamìfero não humano quimérico, dispositivo de cultura celular implantável, cápsula biocompatìvel, método para tratamento de uma doença do sistema nervoso, célula de mamìfero, e, método para produzir neurturin ou um seu equivalente funcional |
PL1694354T3 (pl) | 2003-11-27 | 2009-12-31 | Develogen Ag | Sposób zapobiegania i leczenia cukrzycy za pomocą neurturyny |
NZ553420A (en) | 2004-08-19 | 2010-02-26 | Biogen Idec Inc | Refolding transforming growth factor beta family proteins |
KR20110126732A (ko) | 2004-08-19 | 2011-11-23 | 바이오겐 아이덱 엠에이 인코포레이티드 | 뉴블라스틴 변형체 |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
EP2420833B1 (en) * | 2006-05-05 | 2015-09-02 | Opexa Therapeutics | T-cell vaccine |
EP1872790A1 (en) | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | New formulation for increasing bioavailability of neurturin |
ES2476253T3 (es) | 2007-05-01 | 2014-07-14 | Biogen Idec Ma Inc. | P�ptidos de neublastina para su uso en el aumento de la vascularizaci�n en tejido con flujo sanguíneo deteriorado |
EP2192904B1 (en) | 2007-08-27 | 2016-08-17 | Auxagen, Inc. | METHODS FOR INHIBITING TGF-beta |
CA2742839A1 (en) * | 2007-11-05 | 2009-05-14 | Develogen Aktiengesellschaft | Novel neurturin conjugates for pharmaceutical use |
US8487006B2 (en) | 2008-09-16 | 2013-07-16 | Auxagen, Inc. | Method of enhancing TGF-β signalling |
BR112012009801A8 (pt) * | 2009-10-30 | 2016-08-30 | Cns Therapeutics Inc | Polipeptídeo neurturina e variante de neurturina |
US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
US8564522B2 (en) * | 2010-03-31 | 2013-10-22 | Apple Inc. | Reduced-power communications within an electronic display |
NZ704191A (en) | 2010-06-14 | 2016-05-27 | Hoffmann La Roche | Cell-penetrating peptides and uses therof |
EP2394665A1 (en) * | 2010-06-14 | 2011-12-14 | F. Hoffmann-La Roche AG | Cell-penetrating peptides and uses therof |
US9869272B1 (en) | 2011-04-20 | 2018-01-16 | Martin A. Stuart | Performance of a transcritical or supercritical CO2 Rankin cycle engine |
EP2594295A1 (en) | 2011-11-16 | 2013-05-22 | Servicio Andaluz De Salud | Nerve implants based on a compacted biomaterial containing cells |
JP2019502674A (ja) * | 2015-08-25 | 2019-01-31 | ヒスタイド アクツィエンゲゼルシャフト | 組織形成誘導用化合物及びその使用 |
AU2016311298A1 (en) | 2015-08-25 | 2018-02-08 | Histide Ag | Compounds for inducing tissue formation and uses thereof |
BR112018071215A2 (pt) | 2016-04-13 | 2019-02-19 | Universiteit Maastricht | peptídeo para uso no tratamento, melhora ou prevenção de osteoartrite |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141856A (en) * | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
US5011914A (en) * | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
WO1993000616A1 (en) | 1991-06-29 | 1993-01-07 | Kao Corporation | Method of forming fixed images |
HU220795B1 (hu) * | 1991-09-20 | 2002-05-28 | Amgen Inc. | Gliasejtvonal-eredetű neurotróf faktorfehérjék, továbbá berendezések és gyógyászati készítmények idegsejtkárosodás megelőzésére és kezelésére |
CA2170751A1 (en) * | 1993-09-01 | 1995-03-09 | Timothy J. Cunningham | Neuron regulatory factor for promoting neuron survival |
WO1995017203A1 (en) * | 1993-12-22 | 1995-06-29 | The University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
AU716846B2 (en) * | 1996-03-14 | 2000-03-09 | Washington University | Persephin and related growth factors |
-
1995
- 1995-08-28 US US08/519,777 patent/US5739307A/en not_active Expired - Lifetime
-
1996
- 1996-08-27 EP EP96932163A patent/EP0787142B1/en not_active Expired - Lifetime
- 1996-08-27 NZ NZ332921A patent/NZ332921A/en not_active IP Right Cessation
- 1996-08-27 DK DK96932163T patent/DK0787142T3/da active
- 1996-08-27 DE DE69635738T patent/DE69635738T2/de not_active Expired - Lifetime
- 1996-08-27 WO PCT/US1996/014065 patent/WO1997008196A1/en active IP Right Grant
- 1996-08-27 CA CA2194172A patent/CA2194172C/en not_active Expired - Lifetime
- 1996-08-27 IL IL12277496A patent/IL122774A0/xx not_active IP Right Cessation
- 1996-08-27 NZ NZ332922A patent/NZ332922A/xx not_active IP Right Cessation
- 1996-08-27 JP JP51062897A patent/JP4222629B2/ja not_active Expired - Lifetime
- 1996-08-27 AU AU71054/96A patent/AU714107B2/en not_active Expired
- 1996-08-27 NZ NZ318939A patent/NZ318939A/xx not_active IP Right Cessation
- 1996-08-27 AT AT96932163T patent/ATE315578T1/de not_active IP Right Cessation
- 1996-11-01 US US08/742,035 patent/US5747655A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,019 patent/US5817622A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,143 patent/US5843914A/en not_active Expired - Lifetime
- 1996-12-31 US US08/775,414 patent/US6090778A/en not_active Expired - Lifetime
-
1998
- 1998-01-07 MX MX9800277A patent/MX9800277A/es unknown
-
1999
- 1999-12-30 US US09/476,290 patent/US7015311B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7105496A (en) | 1997-03-19 |
EP0787142A1 (en) | 1997-08-06 |
US7015311B1 (en) | 2006-03-21 |
DE69635738D1 (de) | 2006-04-06 |
ATE315578T1 (de) | 2006-02-15 |
DE69635738T2 (de) | 2006-08-31 |
NZ332922A (en) | 1999-07-29 |
EP0787142A4 (en) | 1999-04-07 |
US5843914A (en) | 1998-12-01 |
EP0787142B1 (en) | 2006-01-11 |
WO1997008196A1 (en) | 1997-03-06 |
NZ332921A (en) | 2001-03-30 |
IL122774A0 (en) | 1998-08-16 |
US5739307A (en) | 1998-04-14 |
US6090778A (en) | 2000-07-18 |
MX9800277A (es) | 1998-09-30 |
CA2194172A1 (en) | 1997-03-01 |
JP4222629B2 (ja) | 2009-02-12 |
US5817622A (en) | 1998-10-06 |
US5747655A (en) | 1998-05-05 |
AU714107B2 (en) | 1999-12-16 |
NZ318939A (en) | 1999-01-28 |
JPH11512928A (ja) | 1999-11-09 |
CA2194172C (en) | 2012-07-10 |
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