DK0787142T3 - Neurturin og beslægtede vækstfaktorer - Google Patents
Neurturin og beslægtede vækstfaktorerInfo
- Publication number
- DK0787142T3 DK0787142T3 DK96932163T DK96932163T DK0787142T3 DK 0787142 T3 DK0787142 T3 DK 0787142T3 DK 96932163 T DK96932163 T DK 96932163T DK 96932163 T DK96932163 T DK 96932163T DK 0787142 T3 DK0787142 T3 DK 0787142T3
- Authority
- DK
- Denmark
- Prior art keywords
- neurturin
- methods
- growth factors
- vectors
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/519,777 US5739307A (en) | 1995-08-28 | 1995-08-28 | Polynucleotide encoding neurturin neurotrophic factor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0787142T3 true DK0787142T3 (da) | 2006-05-29 |
Family
ID=24069730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96932163T DK0787142T3 (da) | 1995-08-28 | 1996-08-27 | Neurturin og beslægtede vækstfaktorer |
Country Status (12)
Country | Link |
---|---|
US (6) | US5739307A (ja) |
EP (1) | EP0787142B1 (ja) |
JP (1) | JP4222629B2 (ja) |
AT (1) | ATE315578T1 (ja) |
AU (1) | AU714107B2 (ja) |
CA (1) | CA2194172C (ja) |
DE (1) | DE69635738T2 (ja) |
DK (1) | DK0787142T3 (ja) |
IL (1) | IL122774A0 (ja) |
MX (1) | MX9800277A (ja) |
NZ (3) | NZ318939A (ja) |
WO (1) | WO1997008196A1 (ja) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743628B1 (en) * | 1995-08-28 | 2004-06-01 | Washington University | Method of cell culture using neurturin |
US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
US6222022B1 (en) | 1996-03-14 | 2001-04-24 | Washington University | Persephin and related growth factors |
US6716600B1 (en) * | 1996-03-14 | 2004-04-06 | Washington University | Persephin and related growth factors |
ES2237793T3 (es) * | 1996-03-14 | 2005-08-01 | Washington University | Persefina y factores de crecimiento relacionados. |
ES2293662T3 (es) | 1996-11-15 | 2008-03-16 | Genentech, Inc. | Purificacion de neurotrofinas. |
NZ501423A (en) * | 1997-04-17 | 2002-02-01 | Univ Washington | Receptors for TGF-beta-related neurotrophic factors and use for treating disease |
US7723473B2 (en) * | 1997-06-19 | 2010-05-25 | St. Louis University | Peptide antagonists of TGF-beta family members and therapeutic uses thereof |
US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
EP1304119A3 (en) * | 1997-07-30 | 2004-01-21 | Amgen Inc. | Method for preventing and treating hearing loss using a neurturin protein product |
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
PL209952B1 (pl) * | 1998-07-14 | 2011-11-30 | Janssen Pharmaceutica Nv | Wyizolowana cząsteczka kwasu nukleinowego, wyizolowany ludzki neurotroficzny czynnik wzrostu, plazmid, wektor ekspresyjny, komórka gospodarza, zastosowania cząsteczki kwasu nukleinowego, zastosowania neurotroficznego czynnika wzrostu, kompozycje faramaceutyczne, przeciwciało oraz sposób wykrywania neurotroficznego czynnika wzrostu |
US6268352B1 (en) * | 1998-09-02 | 2001-07-31 | The Regents Of The University Of California | Promoters of neural regeneration |
US6284540B1 (en) * | 1998-09-29 | 2001-09-04 | Washington University | Artemin, a novel neurotrophic factor |
ES2316194T3 (es) * | 1998-10-28 | 2009-04-01 | Cornell Research Foundation, Inc. | Metodos para la regulacion de la angiogenesis y la integridad vascular utilizando los ligandos bdnf, nt-3 y nt-4. |
DK1175433T3 (da) | 1999-05-04 | 2005-09-19 | Strakan Int Ltd | Androgenglycosider og androgen aktivitet deraf |
CA2372119A1 (en) * | 1999-05-17 | 2000-11-23 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Und Zum Vertrie B Von Pharmaka Mbh | Neuroprotective properties of gdf-15, a novel member of the tgf-.beta. superfamily |
DE60045045D1 (de) * | 1999-11-05 | 2010-11-11 | Hexima Ltd | Nukleinsäuremoleküle zur kodierung cyclisierbare aminosäuresequenzen |
US6866851B1 (en) | 1999-12-28 | 2005-03-15 | Washington University | GFRα1-RET specific agonists and methods therefor |
GB0024550D0 (ja) | 2000-10-06 | 2000-11-22 | Oxford Biomedica Ltd | |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
AU2002250203B2 (en) | 2001-03-28 | 2006-08-10 | Biogen Ma Inc. | Use of neublastin polypeptides for treating neuropathic pain |
US7658926B2 (en) * | 2001-09-14 | 2010-02-09 | Opexa Pharmaceuticals, Inc. | Autologous T-cell vaccines materials and methods |
US20050222070A1 (en) * | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
EP1507553A2 (en) | 2002-05-29 | 2005-02-23 | DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung | Pancreas-specific proteins |
BRPI0305769A8 (pt) * | 2002-08-08 | 2017-09-12 | Baylor College Medicine | Isolamento e identificação de células t |
CA2522364C (en) | 2003-04-18 | 2014-12-09 | Biogen Idec Ma Inc. | Polymer-conjugated glycosylated neublastin |
WO2004104172A2 (en) * | 2003-05-15 | 2004-12-02 | Bioarray Solutions, Ltd. | Hybridization-mediated analysis of polymorphisms |
WO2004108760A2 (en) | 2003-06-10 | 2004-12-16 | Nsgene A/S | Improved secretion of neublastin |
ATE493504T1 (de) * | 2003-09-12 | 2011-01-15 | Stemcell Technologies Inc | Test für neurale koloniebildung |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
NZ547185A (en) | 2003-10-20 | 2009-03-31 | Nsgene As | In vivo gene therapy of parkinson's disease |
PL1694354T3 (pl) | 2003-11-27 | 2009-12-31 | Develogen Ag | Sposób zapobiegania i leczenia cukrzycy za pomocą neurturyny |
SI1786454T1 (sl) | 2004-08-19 | 2010-10-29 | Biogen Idec Inc | Variante neoblastina |
CA2577690C (en) | 2004-08-19 | 2013-08-06 | Biogen Idec Ma Inc. | Refolding transforming growth factor beta family proteins |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
ES2553192T3 (es) * | 2006-05-05 | 2015-12-04 | Opexa Therapeutics | Vacuna de células T |
EP1872790A1 (en) | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | New formulation for increasing bioavailability of neurturin |
CA2685686A1 (en) | 2007-05-01 | 2008-11-13 | Biogen Idec Ma Inc. | Neublastin polypeptides for use increasing vascularization in a tissue |
EP2192904B1 (en) | 2007-08-27 | 2016-08-17 | Auxagen, Inc. | METHODS FOR INHIBITING TGF-beta |
BRPI0819220A2 (pt) * | 2007-11-05 | 2019-02-26 | Develogen Aktiengessellschaft | proteína neurturina ou fragmento da mesma, sua composição farmacêutica e uso |
WO2010033507A1 (en) | 2008-09-16 | 2010-03-25 | St. Louis University | Method of enhancing tgf-beta signalling |
US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
CA2778678A1 (en) * | 2009-10-30 | 2011-05-05 | Cns Therapeutics, Inc. | Improved neurturin molecules |
US8564522B2 (en) * | 2010-03-31 | 2013-10-22 | Apple Inc. | Reduced-power communications within an electronic display |
JP5726299B2 (ja) | 2010-06-14 | 2015-05-27 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 細胞透過性ペプチドおよびその使用 |
EP2394665A1 (en) * | 2010-06-14 | 2011-12-14 | F. Hoffmann-La Roche AG | Cell-penetrating peptides and uses therof |
US9869272B1 (en) | 2011-04-20 | 2018-01-16 | Martin A. Stuart | Performance of a transcritical or supercritical CO2 Rankin cycle engine |
EP2594295A1 (en) | 2011-11-16 | 2013-05-22 | Servicio Andaluz De Salud | Nerve implants based on a compacted biomaterial containing cells |
EP3341397A2 (en) * | 2015-08-25 | 2018-07-04 | Histide AG | Compounds for inducing tissue formation and uses thereof |
JP7056932B2 (ja) | 2015-08-25 | 2022-04-19 | ヒスタイド アクツィエンゲゼルシャフト | 組織形成誘導用化合物及びその使用 |
AU2017249631A1 (en) * | 2016-04-13 | 2018-11-01 | Academisch Ziekenhuis Maastricht | Method for the treatment or prevention of osteoarthritis |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141856A (en) * | 1989-01-05 | 1992-08-25 | Synergen, Inc. | Expression of purified ciliary neurotrophic factor |
US5011914A (en) * | 1989-01-05 | 1991-04-30 | Collins Franklin D | Purified ciliary neurotrophic factor |
US5260417A (en) * | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
EP0592675A1 (en) | 1991-06-29 | 1994-04-20 | Kao Corporation | Method of forming fixed images |
CA2119463C (en) * | 1991-09-20 | 2003-09-16 | Leu-Fen H. Lin | Glial cell line-derived neutrophic factor |
WO1995006662A1 (en) * | 1993-09-01 | 1995-03-09 | Start Technology Partnership | Neuron regulatory factor for promoting neuron survival |
AU1443095A (en) * | 1993-12-22 | 1995-07-10 | University Of Medicine And Dentistry Of New Jersey | Novel nucleic acid sequences isolated from glial cells |
US5759775A (en) * | 1994-10-27 | 1998-06-02 | Genetech, Inc. | Methods for detecting nucleic acids encoding AL--1 neurotrophic factor |
ES2237793T3 (es) * | 1996-03-14 | 2005-08-01 | Washington University | Persefina y factores de crecimiento relacionados. |
-
1995
- 1995-08-28 US US08/519,777 patent/US5739307A/en not_active Expired - Lifetime
-
1996
- 1996-08-27 AT AT96932163T patent/ATE315578T1/de not_active IP Right Cessation
- 1996-08-27 CA CA2194172A patent/CA2194172C/en not_active Expired - Lifetime
- 1996-08-27 AU AU71054/96A patent/AU714107B2/en not_active Expired
- 1996-08-27 WO PCT/US1996/014065 patent/WO1997008196A1/en active IP Right Grant
- 1996-08-27 EP EP96932163A patent/EP0787142B1/en not_active Expired - Lifetime
- 1996-08-27 JP JP51062897A patent/JP4222629B2/ja not_active Expired - Lifetime
- 1996-08-27 DK DK96932163T patent/DK0787142T3/da active
- 1996-08-27 NZ NZ318939A patent/NZ318939A/xx not_active IP Right Cessation
- 1996-08-27 NZ NZ332922A patent/NZ332922A/xx not_active IP Right Cessation
- 1996-08-27 NZ NZ332921A patent/NZ332921A/en not_active IP Right Cessation
- 1996-08-27 IL IL12277496A patent/IL122774A0/xx not_active IP Right Cessation
- 1996-08-27 DE DE69635738T patent/DE69635738T2/de not_active Expired - Lifetime
- 1996-11-01 US US08/742,035 patent/US5747655A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,019 patent/US5817622A/en not_active Expired - Lifetime
- 1996-12-30 US US08/777,143 patent/US5843914A/en not_active Expired - Lifetime
- 1996-12-31 US US08/775,414 patent/US6090778A/en not_active Expired - Lifetime
-
1998
- 1998-01-07 MX MX9800277A patent/MX9800277A/es unknown
-
1999
- 1999-12-30 US US09/476,290 patent/US7015311B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL122774A0 (en) | 1998-08-16 |
DE69635738D1 (de) | 2006-04-06 |
NZ318939A (en) | 1999-01-28 |
NZ332921A (en) | 2001-03-30 |
EP0787142B1 (en) | 2006-01-11 |
MX9800277A (es) | 1998-09-30 |
CA2194172A1 (en) | 1997-03-01 |
EP0787142A1 (en) | 1997-08-06 |
DE69635738T2 (de) | 2006-08-31 |
US5843914A (en) | 1998-12-01 |
NZ332922A (en) | 1999-07-29 |
AU7105496A (en) | 1997-03-19 |
WO1997008196A1 (en) | 1997-03-06 |
JP4222629B2 (ja) | 2009-02-12 |
AU714107B2 (en) | 1999-12-16 |
CA2194172C (en) | 2012-07-10 |
ATE315578T1 (de) | 2006-02-15 |
US5739307A (en) | 1998-04-14 |
US6090778A (en) | 2000-07-18 |
JPH11512928A (ja) | 1999-11-09 |
US5817622A (en) | 1998-10-06 |
US7015311B1 (en) | 2006-03-21 |
EP0787142A4 (en) | 1999-04-07 |
US5747655A (en) | 1998-05-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0787142T3 (da) | Neurturin og beslægtede vækstfaktorer | |
DE69731834D1 (de) | Agouti verwandtes gen | |
NO20065528L (no) | Forbindelser som fremmer vevsvekst. | |
EP0861894A4 (en) | POLYPEPTIDE THAT SUPPRESSES DIFFERENTIATION | |
NZ279963A (en) | Human tissue inhibitor of metalloproteinase-4 (timp-4) and dna (rna) encoding polypeptide which may be derived from atcc 75946 | |
EP2189475A3 (en) | Fibroblast growth factor-like polypeptides | |
DK0686197T3 (da) | Geminivirusbaseret genekspressionssystem | |
Neuhaus et al. | The human connexin32 gene is transcribed from two tissue-specific promoters | |
WO2002061076A1 (en) | Adiponectin-associated protein | |
EP0886651A4 (en) | PERSEPHIN AND ASSOCIATED GROWTH FACTORS | |
IL133834A0 (en) | Persephin and related growth factors | |
WO2000008157A3 (en) | Human anion transporter genes atnov | |
EP1260228A3 (en) | Human growth gene and short stature gene region. Therapeutic uses | |
EP0816504A3 (en) | Platelet activating factor acetylhdrolase, and gene thereof | |
CY1110911T1 (el) | Ανθρωπινο γονιδιο tsc403 | |
RU2003123108A (ru) | Мутантные формы человеческого белка fgf23, снижающие содержание фосфора в крови | |
AU5327198A (en) | Nucleotide sequence coding for a flavin-containing monooxygenase, corresponding protein and their applications in the fields of diagnosis and therapy | |
EP0990000A4 (en) | CONJUNCTIVE TISSUE GROWTH FACTOR 3 | |
WO2002016419A3 (en) | Progression suppressed gene 13 (psgen 13) and uses thereof | |
EP0787798A3 (en) | GRP17 gene | |
Li et al. | Cloning and sequence analysis of two embryonic β-like globin cDNAs (y and z) of hamster | |
范清宇 | A SPECIFIC PROTEIN FOUND IN HUMAN SENESCENT FIBROBLASTS | |
WO1999043834A3 (en) | P-selectin ligand protein, including tetrameric fusion proteins | |
PT89511A (pt) | Processo para a preparacao de anfiregulina, um regulador bifuncional do crescimento de celulas |