IL120259A - Ortho-substituted benzoylguandines, process for their preparation and pharmaceutical or diagnostic compositions containing them - Google Patents

Ortho-substituted benzoylguandines, process for their preparation and pharmaceutical or diagnostic compositions containing them

Info

Publication number
IL120259A
IL120259A IL12025997A IL12025997A IL120259A IL 120259 A IL120259 A IL 120259A IL 12025997 A IL12025997 A IL 12025997A IL 12025997 A IL12025997 A IL 12025997A IL 120259 A IL120259 A IL 120259A
Authority
IL
Israel
Prior art keywords
compound
chloro
preparing
medicament
hydrochloride
Prior art date
Application number
IL12025997A
Other languages
English (en)
Other versions
IL120259A0 (en
Original Assignee
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh
Publication of IL120259A0 publication Critical patent/IL120259A0/xx
Publication of IL120259A publication Critical patent/IL120259A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL12025997A 1996-02-22 1997-02-20 Ortho-substituted benzoylguandines, process for their preparation and pharmaceutical or diagnostic compositions containing them IL120259A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19606509A DE19606509A1 (de) 1996-02-22 1996-02-22 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
IL120259A0 IL120259A0 (en) 1997-06-10
IL120259A true IL120259A (en) 2001-05-20

Family

ID=7786043

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12025997A IL120259A (en) 1996-02-22 1997-02-20 Ortho-substituted benzoylguandines, process for their preparation and pharmaceutical or diagnostic compositions containing them

Country Status (30)

Country Link
US (1) US5856574A (el)
EP (1) EP0791577B1 (el)
JP (1) JP3974677B2 (el)
KR (1) KR100476796B1 (el)
CN (1) CN1060764C (el)
AR (1) AR005933A1 (el)
AT (1) ATE186296T1 (el)
AU (1) AU723096B2 (el)
BR (1) BR9701046A (el)
CA (1) CA2198176A1 (el)
CZ (1) CZ287843B6 (el)
DE (2) DE19606509A1 (el)
DK (1) DK0791577T3 (el)
ES (1) ES2140922T3 (el)
GR (1) GR3032293T3 (el)
HR (1) HRP970101B1 (el)
HU (1) HUP9700502A3 (el)
ID (1) ID16042A (el)
IL (1) IL120259A (el)
MX (1) MX9701323A (el)
MY (1) MY117642A (el)
NO (1) NO307046B1 (el)
NZ (1) NZ314268A (el)
PL (1) PL185752B1 (el)
RU (1) RU2218329C2 (el)
SI (1) SI0791577T1 (el)
SK (1) SK281753B6 (el)
TR (1) TR199700144A2 (el)
TW (1) TW404937B (el)
ZA (1) ZA971514B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713427A1 (de) * 1997-04-01 1998-10-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CN111099959B (zh) * 2019-12-30 2022-09-02 西安瑞联新材料股份有限公司 一种1,4-二溴-2,5-二碘苯的工业化生产方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157351T1 (de) * 1993-02-20 1997-09-15 Hoechst Ag Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
US5596407A (en) * 1995-06-07 1997-01-21 Varian Associates, Inc Optical detector for echelle spectrometer

Also Published As

Publication number Publication date
DE19606509A1 (de) 1997-08-28
IL120259A0 (en) 1997-06-10
EP0791577A1 (de) 1997-08-27
CA2198176A1 (en) 1997-08-22
NO970798L (no) 1997-08-25
DE59700640D1 (de) 1999-12-09
AU1477397A (en) 1997-08-28
HRP970101B1 (en) 2001-02-28
NZ314268A (en) 1997-11-24
HUP9700502A2 (en) 1997-12-29
PL318417A1 (en) 1997-09-01
KR100476796B1 (ko) 2005-07-21
HRP970101A2 (en) 1998-04-30
BR9701046A (pt) 1998-12-15
ES2140922T3 (es) 2000-03-01
CZ287843B6 (en) 2001-02-14
HU9700502D0 (en) 1997-04-28
NO970798D0 (no) 1997-02-21
TR199700144A2 (tr) 1997-09-21
JPH09227496A (ja) 1997-09-02
RU2218329C2 (ru) 2003-12-10
MY117642A (en) 2004-07-31
CN1161960A (zh) 1997-10-15
AU723096B2 (en) 2000-08-17
MX9701323A (es) 1997-08-30
CZ52897A3 (cs) 1998-06-17
TW404937B (en) 2000-09-11
SI0791577T1 (en) 2000-02-29
SK23797A3 (en) 1997-11-05
AR005933A1 (es) 1999-07-21
ZA971514B (en) 1997-08-22
GR3032293T3 (en) 2000-04-27
ATE186296T1 (de) 1999-11-15
PL185752B1 (pl) 2003-07-31
US5856574A (en) 1999-01-05
ID16042A (id) 1997-08-28
SK281753B6 (sk) 2001-07-10
CN1060764C (zh) 2001-01-17
JP3974677B2 (ja) 2007-09-12
EP0791577B1 (de) 1999-11-03
DK0791577T3 (da) 2000-04-25
HUP9700502A3 (en) 1998-01-28
NO307046B1 (no) 2000-01-31
KR970061861A (ko) 1997-09-12

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