IL118239A - Fumarate salt of (R)-5-(methylamino sulphonyl methyl)-3-(N-methyl pyrrolidin-2-ylmethyl)-1 H-indole its preparation and pharmaceutical compositions comprising it - Google Patents

Fumarate salt of (R)-5-(methylamino sulphonyl methyl)-3-(N-methyl pyrrolidin-2-ylmethyl)-1 H-indole its preparation and pharmaceutical compositions comprising it

Info

Publication number
IL118239A
IL118239A IL11823996A IL11823996A IL118239A IL 118239 A IL118239 A IL 118239A IL 11823996 A IL11823996 A IL 11823996A IL 11823996 A IL11823996 A IL 11823996A IL 118239 A IL118239 A IL 118239A
Authority
IL
Israel
Prior art keywords
methyl
ylmethyl
indole
preparation
pharmaceutical compositions
Prior art date
Application number
IL11823996A
Other languages
English (en)
Other versions
IL118239A0 (en
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of IL118239A0 publication Critical patent/IL118239A0/xx
Publication of IL118239A publication Critical patent/IL118239A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11823996A 1995-05-20 1996-05-13 Fumarate salt of (R)-5-(methylamino sulphonyl methyl)-3-(N-methyl pyrrolidin-2-ylmethyl)-1 H-indole its preparation and pharmaceutical compositions comprising it IL118239A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9510223.2A GB9510223D0 (en) 1995-05-20 1995-05-20 Therapeutic agent

Publications (2)

Publication Number Publication Date
IL118239A0 IL118239A0 (en) 1996-09-12
IL118239A true IL118239A (en) 2000-10-31

Family

ID=10774766

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11823996A IL118239A (en) 1995-05-20 1996-05-13 Fumarate salt of (R)-5-(methylamino sulphonyl methyl)-3-(N-methyl pyrrolidin-2-ylmethyl)-1 H-indole its preparation and pharmaceutical compositions comprising it

Country Status (42)

Country Link
US (1) US5994387A (es)
EP (1) EP0827503B1 (es)
JP (1) JP3233940B2 (es)
KR (1) KR100295255B1 (es)
CN (1) CN1063175C (es)
AP (1) AP738A (es)
AR (1) AR003949A1 (es)
AT (1) ATE194986T1 (es)
AU (1) AU701154B2 (es)
BG (1) BG63046B1 (es)
BR (1) BR9610858A (es)
CA (1) CA2219631C (es)
CO (1) CO5040221A1 (es)
CZ (1) CZ287939B6 (es)
DE (1) DE69609504T2 (es)
DK (1) DK0827503T3 (es)
DZ (1) DZ2034A1 (es)
ES (1) ES2148753T3 (es)
GB (1) GB9510223D0 (es)
GR (1) GR3034290T3 (es)
HK (1) HK1017884A1 (es)
HR (1) HRP960223B1 (es)
HU (1) HU217657B (es)
IL (1) IL118239A (es)
IS (1) IS1908B (es)
LV (1) LV11992B (es)
MA (1) MA23876A1 (es)
MX (1) MX9708966A (es)
MY (1) MY132066A (es)
NO (1) NO312068B1 (es)
NZ (1) NZ306448A (es)
OA (1) OA10747A (es)
PL (1) PL183142B1 (es)
PT (1) PT827503E (es)
RU (1) RU2161618C2 (es)
SK (1) SK281782B6 (es)
TN (1) TNSN96074A1 (es)
TR (1) TR199701397T1 (es)
UA (1) UA44320C2 (es)
WO (1) WO1996036632A1 (es)
YU (1) YU29496A (es)
ZA (1) ZA963938B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
US20100266638A1 (en) * 2004-02-26 2010-10-21 Allergan, Inc. Headache treatment method
EP2875020B1 (en) * 2012-07-19 2017-09-06 Boehringer Ingelheim International GmbH Process for the preparation of a fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy- chinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-one

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906406C1 (es) * 1989-03-01 1990-10-25 Goedecke Ag, 1000 Berlin, De
HUT64326A (en) * 1990-10-15 1993-12-28 Pfizer Process for production indole derivatives and pharmaceutical preparations containing these compounds
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
AP486A (en) * 1993-04-27 1996-04-16 Pfizer Indole derivatives.

Also Published As

Publication number Publication date
CN1185152A (zh) 1998-06-17
HUP9801761A3 (en) 1999-06-28
HRP960223A2 (en) 1997-10-31
DE69609504T2 (de) 2000-12-14
KR19990014934A (ko) 1999-02-25
NO975210L (no) 1997-11-13
KR100295255B1 (ko) 2001-08-07
ZA963938B (en) 1997-11-17
BG102053A (en) 1998-06-30
DZ2034A1 (fr) 2002-07-21
EP0827503A1 (en) 1998-03-11
OA10747A (en) 2002-12-11
MX9708966A (es) 1998-03-31
LV11992B (en) 1998-06-20
IS1908B (is) 2003-12-31
LV11992A (lv) 1998-03-20
JP3233940B2 (ja) 2001-12-04
BR9610858A (pt) 1999-07-13
AU5500596A (en) 1996-11-29
SK154197A3 (en) 1999-01-11
TNSN96074A1 (fr) 2005-03-15
AR003949A1 (es) 1998-09-30
CN1063175C (zh) 2001-03-14
TR199701397T1 (xx) 1998-03-21
PL183142B1 (pl) 2002-05-31
PL323143A1 (en) 1998-03-16
PT827503E (pt) 2000-11-30
HU217657B (hu) 2000-03-28
GB9510223D0 (en) 1995-07-19
DK0827503T3 (da) 2000-11-20
US5994387A (en) 1999-11-30
NO312068B1 (no) 2002-03-11
CZ364897A3 (cs) 1998-11-11
GR3034290T3 (en) 2000-12-29
MA23876A1 (fr) 1996-12-31
CA2219631C (en) 2001-01-23
CZ287939B6 (cs) 2001-03-14
EP0827503B1 (en) 2000-07-26
RU2161618C2 (ru) 2001-01-10
AU701154B2 (en) 1999-01-21
IL118239A0 (en) 1996-09-12
MY132066A (en) 2007-09-28
BG63046B1 (bg) 2001-02-28
HUP9801761A2 (hu) 1999-05-28
HRP960223B1 (en) 2000-12-31
HK1017884A1 (en) 1999-12-03
WO1996036632A1 (en) 1996-11-21
ES2148753T3 (es) 2000-10-16
DE69609504D1 (de) 2000-08-31
ATE194986T1 (de) 2000-08-15
UA44320C2 (uk) 2002-02-15
AP738A (en) 1999-03-23
CA2219631A1 (en) 1996-11-21
YU29496A (sh) 1998-12-23
NZ306448A (en) 1998-10-28
IS4605A (is) 1997-10-30
NO975210D0 (no) 1997-11-13
SK281782B6 (sk) 2001-07-10
CO5040221A1 (es) 2001-05-29
AP9600801A0 (en) 1996-04-30
JPH10506639A (ja) 1998-06-30

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB20 Patent renewed for 20 years
MM9K Patent not in force due to non-payment of renewal fees