IL117519A - Substituted benzothienylpiperazines their preparation and pharmaceutical compositions comprising them - Google Patents
Substituted benzothienylpiperazines their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL117519A IL117519A IL11751996A IL11751996A IL117519A IL 117519 A IL117519 A IL 117519A IL 11751996 A IL11751996 A IL 11751996A IL 11751996 A IL11751996 A IL 11751996A IL 117519 A IL117519 A IL 117519A
- Authority
- IL
- Israel
- Prior art keywords
- hydrogen
- pharmaceutical compositions
- alkylcarbonyl
- hydroxy
- integer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41381895A | 1995-03-17 | 1995-03-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117519A0 IL117519A0 (en) | 1996-07-23 |
| IL117519A true IL117519A (en) | 2000-08-31 |
Family
ID=23638775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11751996A IL117519A (en) | 1995-03-17 | 1996-03-17 | Substituted benzothienylpiperazines their preparation and pharmaceutical compositions comprising them |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5801176A (hu) |
| EP (1) | EP0732332B1 (hu) |
| JP (1) | JPH093060A (hu) |
| KR (1) | KR100402510B1 (hu) |
| CN (1) | CN1082959C (hu) |
| AT (1) | ATE211137T1 (hu) |
| AU (1) | AU700077B2 (hu) |
| CA (1) | CA2171695A1 (hu) |
| CZ (1) | CZ80496A3 (hu) |
| DE (1) | DE69618050T2 (hu) |
| DK (1) | DK0732332T3 (hu) |
| ES (1) | ES2170177T3 (hu) |
| HU (1) | HUP9600665A3 (hu) |
| IL (1) | IL117519A (hu) |
| NO (1) | NO315652B1 (hu) |
| NZ (1) | NZ286186A (hu) |
| PL (1) | PL182310B1 (hu) |
| PT (1) | PT732332E (hu) |
| RO (1) | RO117453B1 (hu) |
| RU (1) | RU2157371C2 (hu) |
| SG (1) | SG54269A1 (hu) |
| TW (1) | TW328957B (hu) |
| ZA (1) | ZA962075B (hu) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703083A (en) * | 1996-04-15 | 1997-12-30 | Neurogen Corporation | N-aminoalkyl-1-biphenylenyl-2-carboxamides; new dopamine receptor subtype specific ligands |
| US6642228B1 (en) | 1999-06-24 | 2003-11-04 | Toray Industries, Inc. | α1b-adrenergic receptor antagonists |
| GB0117531D0 (en) * | 2001-02-16 | 2001-09-12 | Aventis Pharm Prod Inc | Novel heterocyclic amide derivatives and their use as dopamine D3 receptor ligands |
| JP4497815B2 (ja) * | 2001-02-16 | 2010-07-07 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | 新規な複素環式アミド誘導体およびドーパミンｄ３受容体リガンドとしてのその使用 |
| JP4497814B2 (ja) * | 2001-02-16 | 2010-07-07 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | 新規複素環式尿素誘導体およびドーパミンｄ３受容体リガンドとしてのそれらの使用 |
| EP1374855A1 (en) * | 2001-03-30 | 2004-01-02 | Takeda Chemical Industries, Ltd. | Medicinal solutions |
| TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| TWI329641B (en) | 2005-08-31 | 2010-09-01 | Otsuka Pharma Co Ltd | (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same |
| CN105985314A (zh) * | 2015-02-05 | 2016-10-05 | 苏州旺山旺水生物医药有限公司 | 布瑞哌唑类似物的制备方法 |
| JPWO2021132311A1 (hu) * | 2019-12-24 | 2021-07-01 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK169601B1 (da) * | 1983-10-17 | 1994-12-19 | Duphar Int Res | Piperazinderivater og farmaceutisk præparat indeholdende et sådant derivat, samt piperazinderivater med mellemproduktanvendelse |
| EP0316723B1 (en) * | 1987-11-20 | 1992-09-30 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-[4(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinones a process for their preparation and their use as medicaments |
| US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| US4968792A (en) * | 1989-09-25 | 1990-11-06 | American Home Products Corporation | Psychotropic benzisothiazole derivatives |
| US5143923B1 (en) * | 1991-04-29 | 1993-11-02 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzoisothiazole-and benzisoxazole-3-carboxamides |
| GB9202915D0 (en) * | 1992-02-12 | 1992-03-25 | Wellcome Found | Chemical compounds |
| US5240927A (en) * | 1992-05-19 | 1993-08-31 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzo[β]thiophen-3-yl piperazines as antipsychotic agents |
| GB9302622D0 (en) * | 1993-02-10 | 1993-03-24 | Wellcome Found | Heteroaromatic compounds |
| US5395835A (en) * | 1994-03-24 | 1995-03-07 | Warner-Lambert Company | Naphthalamides as central nervous system agents |
| GB9410031D0 (en) * | 1994-05-19 | 1994-07-06 | Merck Sharp & Dohme | Therapeutic agents |
-
1996
- 1996-03-11 EP EP96103772A patent/EP0732332B1/en not_active Expired - Lifetime
- 1996-03-11 ES ES96103772T patent/ES2170177T3/es not_active Expired - Lifetime
- 1996-03-11 AT AT96103772T patent/ATE211137T1/de not_active IP Right Cessation
- 1996-03-11 DK DK96103772T patent/DK0732332T3/da active
- 1996-03-11 DE DE69618050T patent/DE69618050T2/de not_active Expired - Fee Related
- 1996-03-11 PT PT96103772T patent/PT732332E/pt unknown
- 1996-03-12 SG SG1996006846A patent/SG54269A1/en unknown
- 1996-03-13 CA CA002171695A patent/CA2171695A1/en not_active Abandoned
- 1996-03-14 AU AU48113/96A patent/AU700077B2/en not_active Ceased
- 1996-03-14 HU HU9600665A patent/HUP9600665A3/hu unknown
- 1996-03-14 ZA ZA9602075A patent/ZA962075B/xx unknown
- 1996-03-14 PL PL96313251A patent/PL182310B1/pl unknown
- 1996-03-15 NZ NZ286186A patent/NZ286186A/en unknown
- 1996-03-15 JP JP8058707A patent/JPH093060A/ja not_active Abandoned
- 1996-03-15 CZ CZ96804A patent/CZ80496A3/cs unknown
- 1996-03-15 RU RU96104547/04A patent/RU2157371C2/ru not_active IP Right Cessation
- 1996-03-15 RO RO96-00568A patent/RO117453B1/ro unknown
- 1996-03-15 CN CN96103608A patent/CN1082959C/zh not_active Expired - Fee Related
- 1996-03-15 NO NO19961077A patent/NO315652B1/no not_active IP Right Cessation
- 1996-03-16 KR KR1019960007100A patent/KR100402510B1/ko not_active IP Right Cessation
- 1996-03-17 IL IL11751996A patent/IL117519A/xx not_active IP Right Cessation
- 1996-05-15 TW TW085105712A patent/TW328957B/zh active
-
1997
- 1997-06-06 US US08/870,988 patent/US5801176A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1139108A (zh) | 1997-01-01 |
| ATE211137T1 (de) | 2002-01-15 |
| JPH093060A (ja) | 1997-01-07 |
| EP0732332B1 (en) | 2001-12-19 |
| TW328957B (en) | 1998-04-01 |
| AU700077B2 (en) | 1998-12-17 |
| IL117519A0 (en) | 1996-07-23 |
| RU2157371C2 (ru) | 2000-10-10 |
| RO117453B1 (ro) | 2002-03-29 |
| NO315652B1 (no) | 2003-10-06 |
| DE69618050D1 (de) | 2002-01-31 |
| DE69618050T2 (de) | 2002-07-11 |
| KR100402510B1 (ko) | 2004-03-18 |
| ES2170177T3 (es) | 2002-08-01 |
| CA2171695A1 (en) | 1996-09-18 |
| CZ80496A3 (en) | 1996-10-16 |
| PT732332E (pt) | 2002-06-28 |
| DK0732332T3 (da) | 2002-04-15 |
| KR960034201A (ko) | 1996-10-22 |
| SG54269A1 (en) | 1998-11-16 |
| EP0732332A1 (en) | 1996-09-18 |
| HUP9600665A3 (en) | 1998-08-28 |
| NO961077L (no) | 1996-09-18 |
| NZ286186A (en) | 1997-07-27 |
| AU4811396A (en) | 1996-09-26 |
| ZA962075B (en) | 1997-12-31 |
| CN1082959C (zh) | 2002-04-17 |
| HUP9600665A2 (en) | 1997-10-28 |
| HU9600665D0 (en) | 1996-05-28 |
| NO961077D0 (no) | 1996-03-15 |
| PL182310B1 (pl) | 2001-12-31 |
| PL313251A1 (en) | 1996-09-30 |
| US5801176A (en) | 1998-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL110151A0 (en) | Amide and urea derivatives and pharmaceutical compositions containing the same | |
| NZ235223A (en) | 10-(1-hydroxyethyl)-11-oxo-1-azatricyclo(7.2.0.0 3,8 )undec-2-ene-2-carboxylic acid derivatives and pharmaceutical compositions | |
| PH23607A (en) | Amide derivatives and pharmaceutical composition containing said compounds | |
| MXPA00006605A (es) | Compuestos de carbonil-indol biciclicos como agentes antiinflamatorios/analgesicos. | |
| JO2321B1 (en) | 4-phenyl-pyridine derivatives | |
| IL117519A (en) | Substituted benzothienylpiperazines their preparation and pharmaceutical compositions comprising them | |
| ZA89389B (en) | Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia | |
| EP1156031A4 (en) | NOVEL COMPOUND, POLYMER PREPARED THEREFROM, AND COMPOSITION CONTAINING THIS POLYMER | |
| GR3034023T3 (en) | Phenyl carboxamide-isoxazole-derivatives and salts, process for their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. | |
| HUT50354A (en) | Process for producing new s-adenosylmethionine decarboxilase inhibitors | |
| DE3787844D1 (de) | Thioester und dessen Verwendung zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen. | |
| IL103595A0 (en) | 2-heterocyclicethylamine derivatives,their preparation and pharmaceutical compositions containing them | |
| EP1142883A4 (en) | HETEROCYCLIC COMPOUNDS AND MEDICINAL COMPOSITIONS THAT CONTAIN THEM | |
| AU625238B2 (en) | Anti-psychotic piperidylbenzimidazole compounds | |
| HU895648D0 (en) | Process for the preparation of n,n-disubstituted diaryl-alkancarboxylic acid amide derivatives and pharmaceutical compositions containing such compounds | |
| IL78780A (en) | 1,3-oxathiane-4-phenyl-5-alkenyl derivatives,their preparation and pharmaceutical compositions containing them | |
| EP0381508A3 (en) | Use of cinnamamide for relaxing muscle tone | |
| IE890161L (en) | 2-Amino Acetamide Derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |