IL117150A - Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them - Google Patents

Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them

Info

Publication number
IL117150A
IL117150A IL11715096A IL11715096A IL117150A IL 117150 A IL117150 A IL 117150A IL 11715096 A IL11715096 A IL 11715096A IL 11715096 A IL11715096 A IL 11715096A IL 117150 A IL117150 A IL 117150A
Authority
IL
Israel
Prior art keywords
preparation
thioureas
medicaments
processes
pharmaceutical compositions
Prior art date
Application number
IL11715096A
Other languages
English (en)
Other versions
IL117150A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL117150A0 publication Critical patent/IL117150A0/xx
Publication of IL117150A publication Critical patent/IL117150A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52Y being a hetero atom
    • C07C311/54Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
    • C07C311/57Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/58Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42Sulfonylthioureas; Sulfonylisothioureas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11715096A 1995-02-17 1996-02-15 Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them IL117150A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19505397A DE19505397A1 (de) 1995-02-17 1995-02-17 Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
IL117150A0 IL117150A0 (en) 1996-06-18
IL117150A true IL117150A (en) 2001-03-19

Family

ID=7754249

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11715096A IL117150A (en) 1995-02-17 1996-02-15 Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them

Country Status (32)

Country Link
US (1) US5652268A (el)
EP (1) EP0727416B1 (el)
JP (1) JP3905568B2 (el)
KR (1) KR100450914B1 (el)
CN (1) CN1058705C (el)
AR (1) AR003924A1 (el)
AT (1) ATE189213T1 (el)
AU (1) AU700793B2 (el)
BR (1) BR9600778A (el)
CA (1) CA2169694C (el)
CY (1) CY2220B1 (el)
CZ (1) CZ291271B6 (el)
DE (2) DE19505397A1 (el)
DK (1) DK0727416T3 (el)
ES (1) ES2143675T3 (el)
FI (1) FI120393B (el)
GR (1) GR3033049T3 (el)
HK (1) HK1011965A1 (el)
HR (1) HRP960077B1 (el)
HU (1) HU226463B1 (el)
IL (1) IL117150A (el)
MY (1) MY113431A (el)
NO (1) NO305751B1 (el)
NZ (1) NZ280991A (el)
PL (1) PL181950B1 (el)
PT (1) PT727416E (el)
RU (1) RU2198163C2 (el)
SI (1) SI9600049B (el)
SK (1) SK281605B6 (el)
TR (1) TR199600118A2 (el)
TW (1) TW355183B (el)
ZA (1) ZA961231B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
DE19647000A1 (de) * 1996-11-14 1998-05-20 Hoechst Ag 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19832009A1 (de) 1998-07-16 2000-01-20 Hoechst Marion Roussel De Gmbh 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate
IL141414A0 (en) * 1998-09-10 2002-03-10 Aventis Pharma Gmbh Use of benzenesulfonyl (thio) ureas for the treatment and prophylaxis of dysfunctions of the autonomous nervous system and use of benzenesulfonyl (thio) ureas in combination with beta-receptor blockers
DE19917233A1 (de) * 1999-04-16 2000-10-19 Aventis Pharma Gmbh Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids
DE19923086A1 (de) 1999-05-20 2000-11-23 Aventis Pharma Gmbh Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054482A1 (de) 2000-11-03 2002-05-08 Aventis Pharma Gmbh Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10054481A1 (de) 2000-11-03 2002-05-08 Aventis Pharma Gmbh Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10129704A1 (de) * 2001-06-22 2003-01-02 Aventis Pharma Gmbh Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks
DE102004061017A1 (de) * 2004-12-18 2006-06-22 Sanofi-Aventis Deutschland Gmbh Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
MY148903A (en) * 2007-06-05 2013-06-14 Sanofi Aventis Di(hetero)arylclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them
WO2023020412A1 (zh) * 2021-08-16 2023-02-23 中国科学院上海药物研究所 磺酰脲化合物、制备方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1198354B (de) * 1963-09-25 1965-08-12 Hoechst Ag Verfahren zur Herstellung von Benzol-sulfonylharnstoffen
DE1518874C3 (de) * 1964-10-07 1975-03-13 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
BE754454A (fr) * 1969-08-06 1971-02-05 Bayer Ag Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide
DE2413514C3 (de) * 1974-03-21 1982-03-04 Hoechst Ag, 6000 Frankfurt N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung
DK0612724T3 (da) * 1993-02-23 1997-06-16 Hoechst Ag Substituerede benzensulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til deres fremstilling og deres anvendelse som farmaceutika

Also Published As

Publication number Publication date
HRP960077B1 (en) 2001-06-30
DE59604262D1 (de) 2000-03-02
JPH08245554A (ja) 1996-09-24
CA2169694C (en) 2008-05-20
NO305751B1 (no) 1999-07-19
AR003924A1 (es) 1998-09-30
RU2198163C2 (ru) 2003-02-10
HU9503879D0 (en) 1996-02-28
CZ43696A3 (en) 1996-09-11
FI960689A (fi) 1996-08-18
TR199600118A2 (tr) 1996-10-21
CA2169694A1 (en) 1996-08-18
PL312528A1 (en) 1996-08-19
SI9600049B (en) 2001-12-31
TW355183B (en) 1999-04-01
KR100450914B1 (ko) 2004-12-03
JP3905568B2 (ja) 2007-04-18
CZ291271B6 (cs) 2003-01-15
ATE189213T1 (de) 2000-02-15
CN1058705C (zh) 2000-11-22
ZA961231B (en) 1996-08-27
HUT73973A (en) 1996-10-28
DK0727416T3 (da) 2000-06-13
ES2143675T3 (es) 2000-05-16
HU226463B1 (en) 2008-12-29
AU700793B2 (en) 1999-01-14
CN1134414A (zh) 1996-10-30
IL117150A0 (en) 1996-06-18
PL181950B1 (pl) 2001-10-31
PT727416E (pt) 2000-06-30
EP0727416A1 (de) 1996-08-21
AU4556096A (en) 1996-08-29
NZ280991A (en) 1997-01-29
EP0727416B1 (de) 2000-01-26
HRP960077A2 (en) 1997-12-31
FI120393B (fi) 2009-10-15
BR9600778A (pt) 1997-12-23
CY2220B1 (en) 2003-04-18
NO960627D0 (no) 1996-02-16
GR3033049T3 (en) 2000-08-31
SK281605B6 (sk) 2001-05-10
FI960689A0 (fi) 1996-02-15
SI9600049A (en) 1996-10-31
HK1011965A1 (en) 1999-07-23
KR960031433A (ko) 1996-09-17
NO960627L (no) 1996-08-19
SK21196A3 (en) 1996-10-02
MY113431A (en) 2002-02-28
DE19505397A1 (de) 1996-08-22
US5652268A (en) 1997-07-29

Similar Documents

Publication Publication Date Title
CA2183972A1 (en) Oxazolidinone derivatives and pharmaceutical compositions containing them
ATE107499T1 (de) Haarkräftigungsmittel.
IL117150A (en) Substituted benzenesulfonylureas and - thioureas processes for their preparation their use in the preparation of medicaments and pharmaceutical compositions containing them
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
FI903153A0 (fi) 11b-aryl-4-estrener, foerfarande foer deras framstaellning samt deras anvaendning som laekemedel.
IT1228288B (it) Composti ad attivita' antiserotoninica
AU656466B2 (en) New benzimidazole compounds, a process for their preparation and pharmaceutical compositions containing them
ES2182454T3 (es) Derivados de amida y su uso terapeutico.
AU2323095A (en) Lactam derivatives useful for pharmaceutical purposes
AU4872793A (en) New ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them
AU6359198A (en) New heterocyclic compounds, a process for their preparation and pharmaceutical compositions containing them
DE69701301D1 (de) Substituierte Benzylderivate von Polyalkylenpolyaminen und ihre Verwendung in kosmetischen und pharmazeutischen Zusammensetzungen
HUT76480A (en) Alkyl-5-methyl-sulphonyl-benzoyl-guanidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them
GR3033175T3 (en) Trifluoromethylsulfonylphenyl or trifluoromethylsulfinylphenyl group containing 2-cyano-3-hydroxy-propenamide derivatives, process for their preparation, their use as medicaments and pharmaceutical compositions containing them
EP0487996B1 (de) 3-substituierte Cephalosporine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PH25187A (en) 3,4-dihydro-2-alkyl-3-oxo-n-aryl-2h-(1)benzothieno (3,2-e)-1,2-thiazine-4-carboxamide-1,1-dioxides, pharmaceutical compositions containing the same and method of use thereof
ZA951334B (en) Acronycine analogues a process for their preparation and the pharmaceutical compositions containing them
DE69608983D1 (de) Thiophenverbindungen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
AU6042094A (en) 4-amino-2-(hetero)aryl-butanamides useful as 5-ht1a-antagonists
GR3015002T3 (en) 1,4-Dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents.
PT83629A (en) Process for the preparation of sulfamoyl urea derivatives and for the herbicidal compositions thereof
HUT58697A (en) Process for producing aryl-pyrrol derivatives and insecticide, acaricide and anthelmintic compositions containing them as active components

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees