IL116526A - Piperazinediones their preparation and pharmaceutical and veterinary compositions containing them - Google Patents

Piperazinediones their preparation and pharmaceutical and veterinary compositions containing them

Info

Publication number
IL116526A
IL116526A IL11652695A IL11652695A IL116526A IL 116526 A IL116526 A IL 116526A IL 11652695 A IL11652695 A IL 11652695A IL 11652695 A IL11652695 A IL 11652695A IL 116526 A IL116526 A IL 116526A
Authority
IL
Israel
Prior art keywords
pct
formula
piperazinediones
pharmaceutical
preparation
Prior art date
Application number
IL11652695A
Other languages
English (en)
Other versions
IL116526A0 (en
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Priority to TW084113835A priority Critical patent/TW307760B/zh
Publication of IL116526A0 publication Critical patent/IL116526A0/xx
Publication of IL116526A publication Critical patent/IL116526A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electron Tubes For Measurement (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11652695A 1994-12-23 1995-12-22 Piperazinediones their preparation and pharmaceutical and veterinary compositions containing them IL116526A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW084113835A TW307760B (en) 1995-12-21 1995-12-23 Piperazinedione derivatives having activity as multi-drug resistance modifying agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9426090.8A GB9426090D0 (en) 1994-12-23 1994-12-23 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
IL116526A0 IL116526A0 (en) 1996-03-31
IL116526A true IL116526A (en) 1999-11-30

Family

ID=10766502

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11652695A IL116526A (en) 1994-12-23 1995-12-22 Piperazinediones their preparation and pharmaceutical and veterinary compositions containing them

Country Status (28)

Country Link
US (1) US5935955A (fr)
EP (1) EP0799210B1 (fr)
JP (1) JPH10511385A (fr)
KR (1) KR100412167B1 (fr)
CN (1) CN1108294C (fr)
AT (1) ATE204569T1 (fr)
AU (1) AU700891B2 (fr)
BG (1) BG63305B1 (fr)
BR (1) BR9510429A (fr)
CA (1) CA2207548A1 (fr)
CZ (1) CZ288935B6 (fr)
DE (1) DE69522342T2 (fr)
DK (1) DK0799210T3 (fr)
ES (1) ES2160726T3 (fr)
FI (1) FI972661A (fr)
GB (2) GB9426090D0 (fr)
HK (1) HK1001974A1 (fr)
HU (1) HUT77740A (fr)
IL (1) IL116526A (fr)
MY (1) MY131762A (fr)
NO (1) NO308532B1 (fr)
NZ (1) NZ297849A (fr)
PL (1) PL186851B1 (fr)
PT (1) PT799210E (fr)
SK (1) SK283385B6 (fr)
UA (1) UA61879C2 (fr)
WO (1) WO1996020180A1 (fr)
ZA (1) ZA9510908B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
MA26696A1 (fr) 1998-10-08 2004-12-20 Smithkline Beecham Plc Derives de tetrahydrobenzazepine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
US6828412B1 (en) * 1999-09-03 2004-12-07 School Of Pharmacy, University Of London Degradable polymers
AU7346400A (en) * 1999-09-03 2001-04-10 School Of Pharmacy, University Of London, The Degradable polymers
CA2385528C (fr) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions et methodes de traitement du cancer utilisant des immunoconjugues et des agents chimiotherapeutiques
ATE377048T1 (de) 2000-09-06 2007-11-15 Ap Pharma Inc Abbaubare polyacetal-polymere
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US20030109448A1 (en) * 2001-11-07 2003-06-12 Crowley Kathleen S. Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
US8710062B2 (en) * 2011-03-11 2014-04-29 Taipei Medical University Piperazinedione compounds
CN103396372B (zh) * 2013-08-09 2015-05-20 中国科学院南海海洋研究所 一类2,5-二酮哌嗪衍生物及其制备方法和在制备抗海洋污损生物防除剂中的应用
AU2019416623B2 (en) * 2018-12-27 2022-12-08 Holosmedic Novel compound and pharmaceutical composition comprising same for enhancing anticancer activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663179A (en) * 1992-07-10 1997-09-02 Laboratoires Glaxo Sa Certain isoquinoline derivatives having anti-tumor properties
GB9217331D0 (en) * 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
US5460977A (en) * 1992-08-14 1995-10-24 Torii & Co. Peptide having allergenicity
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9410387D0 (en) * 1994-05-24 1994-07-13 Xenova Ltd Pharmaceutical compounds

Also Published As

Publication number Publication date
BR9510429A (pt) 1998-07-07
GB2311780A (en) 1997-10-08
EP0799210A1 (fr) 1997-10-08
DE69522342T2 (de) 2002-01-03
BG63305B1 (bg) 2001-09-28
AU4310296A (en) 1996-07-19
CN1176637A (zh) 1998-03-18
PL186851B1 (pl) 2004-03-31
ES2160726T3 (es) 2001-11-16
HK1001974A1 (en) 1998-07-24
WO1996020180A1 (fr) 1996-07-04
FI972661A (fi) 1997-08-22
ATE204569T1 (de) 2001-09-15
GB2311780B (en) 1999-03-03
SK283385B6 (sk) 2003-06-03
NO308532B1 (no) 2000-09-25
PL320915A1 (en) 1997-11-10
MY131762A (en) 2007-08-30
CN1108294C (zh) 2003-05-14
DK0799210T3 (da) 2001-10-01
EP0799210B1 (fr) 2001-08-22
DE69522342D1 (de) 2001-09-27
FI972661A0 (fi) 1997-06-19
HUT77740A (hu) 1998-07-28
US5935955A (en) 1999-08-10
AU700891B2 (en) 1999-01-14
JPH10511385A (ja) 1998-11-04
NO972938L (no) 1997-06-23
CZ190297A3 (cs) 1998-01-14
CZ288935B6 (cs) 2001-09-12
NO972938D0 (no) 1997-06-23
NZ297849A (en) 1999-04-29
CA2207548A1 (fr) 1996-07-04
PT799210E (pt) 2002-01-30
GB9712179D0 (en) 1997-08-13
BG101601A (en) 1998-02-27
KR100412167B1 (ko) 2004-05-27
SK83597A3 (en) 1998-04-08
UA61879C2 (en) 2003-12-15
GB9426090D0 (en) 1995-02-22
ZA9510908B (en) 1996-06-24
IL116526A0 (en) 1996-03-31

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees