IL115905A0 - Sordarin derivatives their preparation and pharmaceutical compositions containing them - Google Patents

Sordarin derivatives their preparation and pharmaceutical compositions containing them

Info

Publication number
IL115905A0
IL115905A0 IL11590595A IL11590595A IL115905A0 IL 115905 A0 IL115905 A0 IL 115905A0 IL 11590595 A IL11590595 A IL 11590595A IL 11590595 A IL11590595 A IL 11590595A IL 115905 A0 IL115905 A0 IL 115905A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
sordarin derivatives
sordarin
Prior art date
Application number
IL11590595A
Other languages
English (en)
Original Assignee
Glaxo Wellcome Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP94500173A external-priority patent/EP0712859A1/fr
Priority claimed from EP94500175A external-priority patent/EP0711784A1/fr
Application filed by Glaxo Wellcome Sa filed Critical Glaxo Wellcome Sa
Publication of IL115905A0 publication Critical patent/IL115905A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11590595A 1994-11-08 1995-11-07 Sordarin derivatives their preparation and pharmaceutical compositions containing them IL115905A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94500173A EP0712859A1 (fr) 1994-11-08 1994-11-08 Dérivés de Sordarin antifongiques
EP94500175A EP0711784A1 (fr) 1994-11-08 1994-11-08 Dérivés de Sordarin antifongiques

Publications (1)

Publication Number Publication Date
IL115905A0 true IL115905A0 (en) 1996-01-31

Family

ID=26137608

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11590595A IL115905A0 (en) 1994-11-08 1995-11-07 Sordarin derivatives their preparation and pharmaceutical compositions containing them

Country Status (35)

Country Link
US (2) US5854280A (fr)
EP (1) EP0753001B1 (fr)
JP (1) JPH09508144A (fr)
KR (1) KR100391401B1 (fr)
CN (1) CN1056849C (fr)
AP (1) AP614A (fr)
AR (1) AR013815A1 (fr)
AT (1) ATE184284T1 (fr)
AU (1) AU704405B2 (fr)
BG (1) BG62620B1 (fr)
BR (1) BR9506473A (fr)
CA (1) CA2179403A1 (fr)
CO (1) CO4520226A1 (fr)
CZ (1) CZ202796A3 (fr)
DE (1) DE69512041T2 (fr)
DK (1) DK0753001T3 (fr)
EE (1) EE9600117A (fr)
ES (1) ES2137549T3 (fr)
FI (1) FI962773A (fr)
GR (1) GR3031677T3 (fr)
HK (1) HK1004222A1 (fr)
HU (1) HU218611B (fr)
IL (1) IL115905A0 (fr)
IS (1) IS4352A (fr)
MX (1) MX9602563A (fr)
NO (1) NO307092B1 (fr)
NZ (1) NZ296091A (fr)
OA (1) OA10303A (fr)
PE (1) PE49696A1 (fr)
RU (1) RU2152398C1 (fr)
SI (1) SI0753001T1 (fr)
SK (1) SK88496A3 (fr)
TW (1) TW321644B (fr)
WO (1) WO1996014326A1 (fr)
ZA (1) ZA959362B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0901493A1 (fr) * 1996-05-08 1999-03-17 Glaxo Wellcome S.A. Procede de preparation d'un compose d'indacene
US6436395B1 (en) * 1996-09-18 2002-08-20 Merck & Co., Inc. Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
US6096511A (en) * 1997-06-10 2000-08-01 Merck & Co., Inc. Protein elongation factor 2 as a target for antifungal and antiparasitic agents
US5965612A (en) * 1997-08-22 1999-10-12 Merck & Co., Inc. 4-cyano-4-deformylsordaricin derivatives
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
SK2092000A3 (en) * 1997-08-22 2001-02-12 Merck & Co Inc 4-cyano-4-deformylsordarin derivatives, process for the preparation thereof and agricultural agent containing the same and use thereof
US6136853A (en) * 1997-10-03 2000-10-24 Merck & Co., Inc. Sordarin derivatives
FI974385A0 (fi) 1997-12-01 1997-12-01 Xyrofin Oy Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
US7070965B1 (en) * 1998-04-14 2006-07-04 Zhenhua Yang Small molecule anticancer compounds and related production process
MA26628A1 (fr) * 1998-05-11 2004-12-20 Glaxo Wellcome Sa Morpholino ethers
WO2000024728A1 (fr) 1998-10-26 2000-05-04 Merck & Co., Inc. Produit de transformation microbienne
CA2371728C (fr) 1999-06-11 2009-06-02 Neorx Corporation Complexe a forte dose de radionucleides destine a la suppression de la moelle osseuse
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6645960B1 (en) 1999-11-11 2003-11-11 Glaxo Wellcome S.A. Antifungal sordaricin derivatives
US6436930B1 (en) * 2000-09-15 2002-08-20 Bristol-Myers Squibb Company Thio derivatives of sordarin as antifungal agents
JP2004536034A (ja) * 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
WO2003007878A2 (fr) 2001-07-18 2003-01-30 Merck & Co., Inc. Agents antifongiques de derives de sordarine
AU2002364552A1 (en) 2001-12-13 2003-06-30 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
AU2002351340A1 (en) * 2001-12-14 2003-06-30 Merck & Co., Inc. A novel sordarin derivative isolated from culture fermentations and functions as an antifungal agent
JP2006513235A (ja) * 2002-12-31 2006-04-20 ネクター セラピューティクス 真菌感染症療法のためのエアゾール化可能な医薬製剤
US9314524B2 (en) 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US8419948B2 (en) * 2009-11-22 2013-04-16 United Laboratories International, Llc Wastewater treatment
WO2012033427A1 (fr) * 2010-09-08 2012-03-15 Dalin Mikhail Viktorovich Procédé de traitement des infections mycosiques et produit pour sa mise en oeuvre
RU2630403C2 (ru) * 2016-02-25 2017-09-07 Жанна Владимировна Вараткова Абразивная масса для изготовления инструмента с высокими номерами структуры

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH465771A (de) * 1965-12-06 1968-11-30 Sandoz Ag Verfahren zur Herstellung eines neuen Antibioticums
JPH0615555B2 (ja) * 1985-08-14 1994-03-02 三共株式会社 抗生物質ゾフイマリン
JP3189443B2 (ja) * 1992-11-20 2001-07-16 萬有製薬株式会社 抗真菌性物質ｂｅ−３１４０５
ATE248625T1 (de) * 1996-09-12 2003-09-15 Merck & Co Inc Fungizide kombinationstherapie

Also Published As

Publication number Publication date
CA2179403A1 (fr) 1996-05-17
FI962773A0 (fi) 1996-07-05
DK0753001T3 (da) 2000-05-08
MX9602563A (es) 1997-05-31
GR3031677T3 (en) 2000-02-29
CN1143965A (zh) 1997-02-26
CN1056849C (zh) 2000-09-27
RU2152398C1 (ru) 2000-07-10
AR013815A1 (es) 2001-01-31
CZ202796A3 (en) 1997-02-12
EP0753001B1 (fr) 1999-09-08
AP9600824A0 (en) 1996-07-31
ES2137549T3 (es) 1999-12-16
KR100391401B1 (ko) 2003-12-31
EP0753001A1 (fr) 1997-01-15
NO962856D0 (no) 1996-07-05
AU3980995A (en) 1996-05-31
HK1004222A1 (en) 1998-11-20
BG62620B1 (en) 2000-03-31
US5854280A (en) 1998-12-29
AP614A (en) 1997-09-05
SK88496A3 (en) 1997-04-09
DE69512041D1 (de) 1999-10-14
HU218611B (hu) 2000-10-28
NZ296091A (en) 1998-06-26
HUT76292A (en) 1997-07-28
ATE184284T1 (de) 1999-09-15
JPH09508144A (ja) 1997-08-19
BG100699A (bg) 1997-02-28
AU704405B2 (en) 1999-04-22
PE49696A1 (es) 1996-12-05
TW321644B (fr) 1997-12-01
OA10303A (en) 1997-10-07
US5952334A (en) 1999-09-14
CO4520226A1 (es) 1997-10-15
ZA959362B (en) 1996-05-08
IS4352A (is) 1996-06-10
DE69512041T2 (de) 2000-02-03
SI0753001T1 (en) 1999-12-31
NO307092B1 (no) 2000-02-07
BR9506473A (pt) 1997-10-07
HU9601865D0 (en) 1996-11-28
FI962773A (fi) 1996-08-26
EE9600117A (et) 1997-04-15
NO962856L (no) 1996-09-05
WO1996014326A1 (fr) 1996-05-17

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