BG62620B1 - Carbocyclic compounds - Google Patents

Carbocyclic compounds

Info

Publication number
BG62620B1
BG62620B1 BG100699A BG10069996A BG62620B1 BG 62620 B1 BG62620 B1 BG 62620B1 BG 100699 A BG100699 A BG 100699A BG 10069996 A BG10069996 A BG 10069996A BG 62620 B1 BG62620 B1 BG 62620B1
Authority
BG
Bulgaria
Prior art keywords
carbocyclic compounds
carbocyclic
compounds
terahydropyrano
medicine
Prior art date
Application number
BG100699A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100699A (bg
Inventor
Jose R. Gomez
Jose M. Calderon
Silvestre Garcia-Ochoa Dorado
Maria T. Fraile Gabaldon
Julia C. Pichel
Jose Fiandor Roman
Domingo Garsallo Viola
Juan C. Cueva Zurita
Jose L. Lavandera Diaz
Sophie Huss
Original Assignee
Glaxo Wellcome S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP94500173A external-priority patent/EP0712859A1/fr
Priority claimed from EP94500175A external-priority patent/EP0711784A1/fr
Application filed by Glaxo Wellcome S.A. filed Critical Glaxo Wellcome S.A.
Publication of BG100699A publication Critical patent/BG100699A/bg
Publication of BG62620B1 publication Critical patent/BG62620B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG100699A 1994-11-08 1996-07-05 Carbocyclic compounds BG62620B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94500173A EP0712859A1 (fr) 1994-11-08 1994-11-08 Dérivés de Sordarin antifongiques
EP94500175A EP0711784A1 (fr) 1994-11-08 1994-11-08 Dérivés de Sordarin antifongiques
PCT/EP1995/004331 WO1996014326A1 (fr) 1994-11-08 1995-11-06 Derives de sordaridine a action antifongique

Publications (2)

Publication Number Publication Date
BG100699A BG100699A (bg) 1997-02-28
BG62620B1 true BG62620B1 (en) 2000-03-31

Family

ID=26137608

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100699A BG62620B1 (en) 1994-11-08 1996-07-05 Carbocyclic compounds

Country Status (35)

Country Link
US (2) US5854280A (fr)
EP (1) EP0753001B1 (fr)
JP (1) JPH09508144A (fr)
KR (1) KR100391401B1 (fr)
CN (1) CN1056849C (fr)
AP (1) AP614A (fr)
AR (1) AR013815A1 (fr)
AT (1) ATE184284T1 (fr)
AU (1) AU704405B2 (fr)
BG (1) BG62620B1 (fr)
BR (1) BR9506473A (fr)
CA (1) CA2179403A1 (fr)
CO (1) CO4520226A1 (fr)
CZ (1) CZ202796A3 (fr)
DE (1) DE69512041T2 (fr)
DK (1) DK0753001T3 (fr)
EE (1) EE9600117A (fr)
ES (1) ES2137549T3 (fr)
FI (1) FI962773A (fr)
GR (1) GR3031677T3 (fr)
HK (1) HK1004222A1 (fr)
HU (1) HU218611B (fr)
IL (1) IL115905A0 (fr)
IS (1) IS4352A (fr)
MX (1) MX9602563A (fr)
NO (1) NO307092B1 (fr)
NZ (1) NZ296091A (fr)
OA (1) OA10303A (fr)
PE (1) PE49696A1 (fr)
RU (1) RU2152398C1 (fr)
SI (1) SI0753001T1 (fr)
SK (1) SK88496A3 (fr)
TW (1) TW321644B (fr)
WO (1) WO1996014326A1 (fr)
ZA (1) ZA959362B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0901493A1 (fr) * 1996-05-08 1999-03-17 Glaxo Wellcome S.A. Procede de preparation d'un compose d'indacene
US6436395B1 (en) * 1996-09-18 2002-08-20 Merck & Co., Inc. Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
US6096511A (en) * 1997-06-10 2000-08-01 Merck & Co., Inc. Protein elongation factor 2 as a target for antifungal and antiparasitic agents
US5965612A (en) * 1997-08-22 1999-10-12 Merck & Co., Inc. 4-cyano-4-deformylsordaricin derivatives
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
SK2092000A3 (en) * 1997-08-22 2001-02-12 Merck & Co Inc 4-cyano-4-deformylsordarin derivatives, process for the preparation thereof and agricultural agent containing the same and use thereof
US6136853A (en) * 1997-10-03 2000-10-24 Merck & Co., Inc. Sordarin derivatives
FI974385A0 (fi) 1997-12-01 1997-12-01 Xyrofin Oy Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
US7070965B1 (en) * 1998-04-14 2006-07-04 Zhenhua Yang Small molecule anticancer compounds and related production process
MA26628A1 (fr) * 1998-05-11 2004-12-20 Glaxo Wellcome Sa Morpholino ethers
WO2000024728A1 (fr) 1998-10-26 2000-05-04 Merck & Co., Inc. Produit de transformation microbienne
CA2371728C (fr) 1999-06-11 2009-06-02 Neorx Corporation Complexe a forte dose de radionucleides destine a la suppression de la moelle osseuse
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6645960B1 (en) 1999-11-11 2003-11-11 Glaxo Wellcome S.A. Antifungal sordaricin derivatives
US6436930B1 (en) * 2000-09-15 2002-08-20 Bristol-Myers Squibb Company Thio derivatives of sordarin as antifungal agents
JP2004536034A (ja) * 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
WO2003007878A2 (fr) 2001-07-18 2003-01-30 Merck & Co., Inc. Agents antifongiques de derives de sordarine
AU2002364552A1 (en) 2001-12-13 2003-06-30 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
AU2002351340A1 (en) * 2001-12-14 2003-06-30 Merck & Co., Inc. A novel sordarin derivative isolated from culture fermentations and functions as an antifungal agent
JP2006513235A (ja) * 2002-12-31 2006-04-20 ネクター セラピューティクス 真菌感染症療法のためのエアゾール化可能な医薬製剤
US9314524B2 (en) 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US8419948B2 (en) * 2009-11-22 2013-04-16 United Laboratories International, Llc Wastewater treatment
WO2012033427A1 (fr) * 2010-09-08 2012-03-15 Dalin Mikhail Viktorovich Procédé de traitement des infections mycosiques et produit pour sa mise en oeuvre
RU2630403C2 (ru) * 2016-02-25 2017-09-07 Жанна Владимировна Вараткова Абразивная масса для изготовления инструмента с высокими номерами структуры

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH465771A (de) * 1965-12-06 1968-11-30 Sandoz Ag Verfahren zur Herstellung eines neuen Antibioticums
JPH0615555B2 (ja) * 1985-08-14 1994-03-02 三共株式会社 抗生物質ゾフイマリン
JP3189443B2 (ja) * 1992-11-20 2001-07-16 萬有製薬株式会社 抗真菌性物質be−31405
ATE248625T1 (de) * 1996-09-12 2003-09-15 Merck & Co Inc Fungizide kombinationstherapie

Also Published As

Publication number Publication date
CA2179403A1 (fr) 1996-05-17
FI962773A0 (fi) 1996-07-05
DK0753001T3 (da) 2000-05-08
MX9602563A (es) 1997-05-31
GR3031677T3 (en) 2000-02-29
CN1143965A (zh) 1997-02-26
CN1056849C (zh) 2000-09-27
RU2152398C1 (ru) 2000-07-10
AR013815A1 (es) 2001-01-31
CZ202796A3 (en) 1997-02-12
EP0753001B1 (fr) 1999-09-08
AP9600824A0 (en) 1996-07-31
ES2137549T3 (es) 1999-12-16
KR100391401B1 (ko) 2003-12-31
EP0753001A1 (fr) 1997-01-15
NO962856D0 (no) 1996-07-05
AU3980995A (en) 1996-05-31
HK1004222A1 (en) 1998-11-20
US5854280A (en) 1998-12-29
AP614A (en) 1997-09-05
SK88496A3 (en) 1997-04-09
DE69512041D1 (de) 1999-10-14
HU218611B (hu) 2000-10-28
NZ296091A (en) 1998-06-26
HUT76292A (en) 1997-07-28
ATE184284T1 (de) 1999-09-15
JPH09508144A (ja) 1997-08-19
BG100699A (bg) 1997-02-28
AU704405B2 (en) 1999-04-22
PE49696A1 (es) 1996-12-05
TW321644B (fr) 1997-12-01
OA10303A (en) 1997-10-07
US5952334A (en) 1999-09-14
CO4520226A1 (es) 1997-10-15
ZA959362B (en) 1996-05-08
IS4352A (is) 1996-06-10
DE69512041T2 (de) 2000-02-03
SI0753001T1 (en) 1999-12-31
NO307092B1 (no) 2000-02-07
BR9506473A (pt) 1997-10-07
IL115905A0 (en) 1996-01-31
HU9601865D0 (en) 1996-11-28
FI962773A (fi) 1996-08-26
EE9600117A (et) 1997-04-15
NO962856L (no) 1996-09-05
WO1996014326A1 (fr) 1996-05-17

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