EE9600117A - Antifungaalsed sordariini derivaadid - Google Patents

Antifungaalsed sordariini derivaadid

Info

Publication number
EE9600117A
EE9600117A EE9600117A EE9600117A EE9600117A EE 9600117 A EE9600117 A EE 9600117A EE 9600117 A EE9600117 A EE 9600117A EE 9600117 A EE9600117 A EE 9600117A EE 9600117 A EE9600117 A EE 9600117A
Authority
EE
Estonia
Prior art keywords
herrine
antifungal
derivatives
herrine derivatives
antifungal herrine
Prior art date
Application number
EE9600117A
Other languages
English (en)
Inventor
Maria Bueno Calderon Jose
Castro Pichel Julia
Carlos Cueva Zurita Juan
Luis Lavandera Diaz Jose
Ramon Ruiz Gomez Jose
Garcia-Ochoa Dorado Silvestre
Teresa Fraile Gabaldon Maria
Fiandor Roman Jose
Garsallo Viola Domingo
Huss Sophie
Original Assignee
Glaxo Wellcome S.A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP94500173A external-priority patent/EP0712859A1/en
Priority claimed from EP94500175A external-priority patent/EP0711784A1/en
Application filed by Glaxo Wellcome S.A filed Critical Glaxo Wellcome S.A
Publication of EE9600117A publication Critical patent/EE9600117A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EE9600117A 1994-11-08 1995-11-06 Antifungaalsed sordariini derivaadid EE9600117A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94500173A EP0712859A1 (en) 1994-11-08 1994-11-08 Antifungal Sordarin derivatives
EP94500175A EP0711784A1 (en) 1994-11-08 1994-11-08 Antifungal Sordarin derivatives
PCT/EP1995/004331 WO1996014326A1 (en) 1994-11-08 1995-11-06 Antifungal sordaridin derivatives

Publications (1)

Publication Number Publication Date
EE9600117A true EE9600117A (et) 1997-04-15

Family

ID=26137608

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600117A EE9600117A (et) 1994-11-08 1995-11-06 Antifungaalsed sordariini derivaadid

Country Status (35)

Country Link
US (2) US5854280A (et)
EP (1) EP0753001B1 (et)
JP (1) JPH09508144A (et)
KR (1) KR100391401B1 (et)
CN (1) CN1056849C (et)
AP (1) AP614A (et)
AR (1) AR013815A1 (et)
AT (1) ATE184284T1 (et)
AU (1) AU704405B2 (et)
BG (1) BG62620B1 (et)
BR (1) BR9506473A (et)
CA (1) CA2179403A1 (et)
CO (1) CO4520226A1 (et)
CZ (1) CZ202796A3 (et)
DE (1) DE69512041T2 (et)
DK (1) DK0753001T3 (et)
EE (1) EE9600117A (et)
ES (1) ES2137549T3 (et)
FI (1) FI962773A (et)
GR (1) GR3031677T3 (et)
HK (1) HK1004222A1 (et)
HU (1) HU218611B (et)
IL (1) IL115905A0 (et)
IS (1) IS4352A (et)
MX (1) MX9602563A (et)
NO (1) NO307092B1 (et)
NZ (1) NZ296091A (et)
OA (1) OA10303A (et)
PE (1) PE49696A1 (et)
RU (1) RU2152398C1 (et)
SI (1) SI0753001T1 (et)
SK (1) SK88496A3 (et)
TW (1) TW321644B (et)
WO (1) WO1996014326A1 (et)
ZA (1) ZA959362B (et)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0901493A1 (en) * 1996-05-08 1999-03-17 Glaxo Wellcome S.A. Process for the preparation of an indacene compound
US6436395B1 (en) 1996-09-18 2002-08-20 Merck & Co., Inc. Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
US6096511A (en) * 1997-06-10 2000-08-01 Merck & Co., Inc. Protein elongation factor 2 as a target for antifungal and antiparasitic agents
US5965612A (en) * 1997-08-22 1999-10-12 Merck & Co., Inc. 4-cyano-4-deformylsordaricin derivatives
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
CA2300407C (en) * 1997-08-22 2010-01-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
US6136853A (en) * 1997-10-03 2000-10-24 Merck & Co., Inc. Sordarin derivatives
FI974385A0 (fi) * 1997-12-01 1997-12-01 Xyrofin Oy Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
US7070965B1 (en) * 1998-04-14 2006-07-04 Zhenhua Yang Small molecule anticancer compounds and related production process
MA26628A1 (fr) * 1998-05-11 2004-12-20 Glaxo Wellcome Sa Morpholino ethers
WO2000024728A1 (en) 1998-10-26 2000-05-04 Merck & Co., Inc. Microbial transformation product
JP2003501488A (ja) 1999-06-11 2003-01-14 ネオルックス コーポレイション 骨髄抑制のための高投与量放射性核種錯体
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6645960B1 (en) 1999-11-11 2003-11-11 Glaxo Wellcome S.A. Antifungal sordaricin derivatives
AU2001289063A1 (en) * 2000-09-15 2002-03-26 Bristol-Myers Squibb Company Novel thio derivatives of sordarin as antifungal agents
AU2002249935A1 (en) * 2001-01-08 2002-08-19 Neorx Corporation Radioactively labelled conjugates of phosphonates
WO2003007878A2 (en) 2001-07-18 2003-01-30 Merck & Co., Inc. Antifungal agents of sordarin derivatives
US7045116B2 (en) 2001-12-13 2006-05-16 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
AU2002351340A1 (en) * 2001-12-14 2003-06-30 Merck & Co., Inc. A novel sordarin derivative isolated from culture fermentations and functions as an antifungal agent
JP2006513235A (ja) * 2002-12-31 2006-04-20 ネクター セラピューティクス 真菌感染症療法のためのエアゾール化可能な医薬製剤
US9314524B2 (en) 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US8419948B2 (en) * 2009-11-22 2013-04-16 United Laboratories International, Llc Wastewater treatment
WO2012033427A1 (ru) * 2010-09-08 2012-03-15 Dalin Mikhail Viktorovich Способ лечения микотических инфекций и препарат для его осуществления
RU2630403C2 (ru) * 2016-02-25 2017-09-07 Жанна Владимировна Вараткова Абразивная масса для изготовления инструмента с высокими номерами структуры

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH465771A (de) * 1965-12-06 1968-11-30 Sandoz Ag Verfahren zur Herstellung eines neuen Antibioticums
JPH0615555B2 (ja) * 1985-08-14 1994-03-02 三共株式会社 抗生物質ゾフイマリン
JP3189443B2 (ja) * 1992-11-20 2001-07-16 萬有製薬株式会社 抗真菌性物質ｂｅ−３１４０５
EA002469B1 (ru) * 1996-09-12 2002-06-27 Мерк Энд Ко., Инк. Способ лечения грибковой инфекции

Also Published As

Publication number Publication date
NO962856L (no) 1996-09-05
SI0753001T1 (en) 1999-12-31
HK1004222A1 (en) 1998-11-20
CN1143965A (zh) 1997-02-26
AU704405B2 (en) 1999-04-22
ZA959362B (en) 1996-05-08
MX9602563A (es) 1997-05-31
CO4520226A1 (es) 1997-10-15
AP9600824A0 (en) 1996-07-31
CA2179403A1 (en) 1996-05-17
EP0753001B1 (en) 1999-09-08
PE49696A1 (es) 1996-12-05
IS4352A (is) 1996-06-10
US5952334A (en) 1999-09-14
OA10303A (en) 1997-10-07
DK0753001T3 (da) 2000-05-08
DE69512041T2 (de) 2000-02-03
EP0753001A1 (en) 1997-01-15
IL115905A0 (en) 1996-01-31
NZ296091A (en) 1998-06-26
BR9506473A (pt) 1997-10-07
NO307092B1 (no) 2000-02-07
BG100699A (bg) 1997-02-28
CN1056849C (zh) 2000-09-27
CZ202796A3 (en) 1997-02-12
ES2137549T3 (es) 1999-12-16
AP614A (en) 1997-09-05
FI962773A0 (fi) 1996-07-05
RU2152398C1 (ru) 2000-07-10
JPH09508144A (ja) 1997-08-19
DE69512041D1 (de) 1999-10-14
WO1996014326A1 (en) 1996-05-17
HUT76292A (en) 1997-07-28
ATE184284T1 (de) 1999-09-15
HU218611B (hu) 2000-10-28
AR013815A1 (es) 2001-01-31
GR3031677T3 (en) 2000-02-29
FI962773A (fi) 1996-08-26
NO962856D0 (no) 1996-07-05
KR100391401B1 (ko) 2003-12-31
TW321644B (et) 1997-12-01
BG62620B1 (en) 2000-03-31
HU9601865D0 (en) 1996-11-28
AU3980995A (en) 1996-05-31
SK88496A3 (en) 1997-04-09
US5854280A (en) 1998-12-29

Similar Documents

Publication Publication Date Title
NO304430B1 (no) Antifungale midler
NO952854D0 (no) 1-arylpyrimidin-derivater
DE59508427D1 (de) 3-aryl-4-hydroxy-delta 3 -dihydrothiophenon-derivate
ATE184284T1 (de) Antifungale sordaridin-derivate
ATA147195A (de) Alkoxyphenyl-substituierte bisbenzoylphosphinoxide
ATA163695A (de) 2-hydroxyphenyltriazine
DE69430587D1 (de) Pyrimidin-acyclonukleosid-derivate
BR9509793A (pt) Derivados de tiofeneno
FI960367A (fi) Uusia dialkoksipyridinyylibentsimidatsolijohdannaisia
DE69527786T2 (de) Diaminomethyliden-derivate
NO965233D0 (no) Deacetoksytaksol-derivat
FI950710A0 (fi) Fungisidisia 2-imidatsoliini-5-onejohdannaisia
DE69521745T2 (de) Diazacycloalkanalkylsulfonamid-derivat
KR950033309U (ko) 줄연장
DE59509209D1 (de) Diphenyloxazolin-derivate
NO970144D0 (no) Trifluormetylkinolinkarboksylsyre-derivat
DE69510792T2 (de) Naphtochinonderivate
BR9509877A (pt) Novos derivados de pirimidinilóxi-e piridimidinilamino- etilfenil-dioxolano
ATA11894A (de) Stauförderbahn
BR9506613A (pt) Derivados de feniltio-oxazolinas
DE9401345U1 (de) Wind-Sturm Ableitungskonstruktion
BR9508450A (pt) Derivados de n-alcóxi-amidina
NO951573D0 (no) Tiadiazinon-derivater
DE69427775T2 (de) Dimethylfurancarboxamilid-derivat
SE9400156D0 (sv) Ställning