IL115905A0 - Sordarin derivatives their preparation and pharmaceutical compositions containing them - Google Patents
Sordarin derivatives their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL115905A0 IL115905A0 IL11590595A IL11590595A IL115905A0 IL 115905 A0 IL115905 A0 IL 115905A0 IL 11590595 A IL11590595 A IL 11590595A IL 11590595 A IL11590595 A IL 11590595A IL 115905 A0 IL115905 A0 IL 115905A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- sordarin derivatives
- sordarin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94500175A EP0711784A1 (en) | 1994-11-08 | 1994-11-08 | Antifungal Sordarin derivatives |
| EP94500173A EP0712859A1 (en) | 1994-11-08 | 1994-11-08 | Antifungal Sordarin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL115905A0 true IL115905A0 (en) | 1996-01-31 |
Family
ID=26137608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11590595A IL115905A0 (en) | 1994-11-08 | 1995-11-07 | Sordarin derivatives their preparation and pharmaceutical compositions containing them |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US5854280A (xx) |
| EP (1) | EP0753001B1 (xx) |
| JP (1) | JPH09508144A (xx) |
| KR (1) | KR100391401B1 (xx) |
| CN (1) | CN1056849C (xx) |
| AP (1) | AP614A (xx) |
| AR (1) | AR013815A1 (xx) |
| AT (1) | ATE184284T1 (xx) |
| AU (1) | AU704405B2 (xx) |
| BG (1) | BG62620B1 (xx) |
| BR (1) | BR9506473A (xx) |
| CA (1) | CA2179403A1 (xx) |
| CO (1) | CO4520226A1 (xx) |
| CZ (1) | CZ202796A3 (xx) |
| DE (1) | DE69512041T2 (xx) |
| DK (1) | DK0753001T3 (xx) |
| EE (1) | EE9600117A (xx) |
| ES (1) | ES2137549T3 (xx) |
| FI (1) | FI962773A (xx) |
| GR (1) | GR3031677T3 (xx) |
| HK (1) | HK1004222A1 (xx) |
| HU (1) | HU218611B (xx) |
| IL (1) | IL115905A0 (xx) |
| IS (1) | IS4352A (xx) |
| MX (1) | MX9602563A (xx) |
| NO (1) | NO307092B1 (xx) |
| NZ (1) | NZ296091A (xx) |
| OA (1) | OA10303A (xx) |
| PE (1) | PE49696A1 (xx) |
| RU (1) | RU2152398C1 (xx) |
| SI (1) | SI0753001T1 (xx) |
| SK (1) | SK88496A3 (xx) |
| TW (1) | TW321644B (xx) |
| WO (1) | WO1996014326A1 (xx) |
| ZA (1) | ZA959362B (xx) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6177457B1 (en) * | 1996-05-08 | 2001-01-23 | Glaxo Wellcome S.A. | Process for the preparation of indacene compound |
| US6436395B1 (en) | 1996-09-18 | 2002-08-20 | Merck & Co., Inc. | Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control |
| US6040463A (en) * | 1996-10-07 | 2000-03-21 | Merck & Co., Inc. | Sordarin derivatives |
| US6096511A (en) * | 1997-06-10 | 2000-08-01 | Merck & Co., Inc. | Protein elongation factor 2 as a target for antifungal and antiparasitic agents |
| US5972996A (en) * | 1997-08-22 | 1999-10-26 | Merck & Co., Inc. | 4-cyano-4-deformylsordarin derivatives |
| US5965612A (en) * | 1997-08-22 | 1999-10-12 | Merck & Co., Inc. | 4-cyano-4-deformylsordaricin derivatives |
| AU740477B2 (en) * | 1997-08-22 | 2001-11-08 | Merck Sharp & Dohme Corp. | 4-cyano-4-deformylsordarin derivatives |
| US6136853A (en) * | 1997-10-03 | 2000-10-24 | Merck & Co., Inc. | Sordarin derivatives |
| FI974385A0 (fi) | 1997-12-01 | 1997-12-01 | Xyrofin Oy | Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning |
| US7070965B1 (en) * | 1998-04-14 | 2006-07-04 | Zhenhua Yang | Small molecule anticancer compounds and related production process |
| MA26628A1 (fr) * | 1998-05-11 | 2004-12-20 | Glaxo Wellcome Sa | Morpholino ethers |
| JP2002528444A (ja) | 1998-10-26 | 2002-09-03 | メルク エンド カムパニー インコーポレーテッド | 微生物変換産物 |
| WO2000076556A2 (en) | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| JP2003513964A (ja) * | 1999-11-11 | 2003-04-15 | グラクソ、ウェルカム、ソシエダッド、アノニマ | 抗真菌性ソルダリシン誘導体 |
| US6436930B1 (en) * | 2000-09-15 | 2002-08-20 | Bristol-Myers Squibb Company | Thio derivatives of sordarin as antifungal agents |
| WO2002062398A2 (en) | 2001-01-08 | 2002-08-15 | Neorx Corporation | Radioactively labelled conjugates of phosphonates |
| WO2003007878A2 (en) | 2001-07-18 | 2003-01-30 | Merck & Co., Inc. | Antifungal agents of sordarin derivatives |
| JP2005516933A (ja) | 2001-12-13 | 2005-06-09 | ダウ グローバル テクノロジーズ インコーポレイティド | 放射性医薬による骨髄炎の治療 |
| JP2005519039A (ja) * | 2001-12-14 | 2005-06-30 | メルク エンド カムパニー インコーポレーテッド | 培養株の発酵産物から単離された新規ソルダリン誘導体及び抗真菌剤としての機能 |
| MXPA05007156A (es) * | 2002-12-31 | 2005-09-21 | Nektar Therapeutics | Formulacion farmaceuticas aerosolizable para terapia para infecciones fungicas. |
| US9314524B2 (en) | 2007-12-31 | 2016-04-19 | Calla Therapeutics Llc | Topical formulations of Flucytosine |
| US8419948B2 (en) * | 2009-11-22 | 2013-04-16 | United Laboratories International, Llc | Wastewater treatment |
| WO2012033427A1 (ru) * | 2010-09-08 | 2012-03-15 | Dalin Mikhail Viktorovich | Способ лечения микотических инфекций и препарат для его осуществления |
| RU2630403C2 (ru) * | 2016-02-25 | 2017-09-07 | Жанна Владимировна Вараткова | Абразивная масса для изготовления инструмента с высокими номерами структуры |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH465771A (de) * | 1965-12-06 | 1968-11-30 | Sandoz Ag | Verfahren zur Herstellung eines neuen Antibioticums |
| JPH0615555B2 (ja) * | 1985-08-14 | 1994-03-02 | 三共株式会社 | 抗生物質ゾフイマリン |
| JP3189443B2 (ja) * | 1992-11-20 | 2001-07-16 | 萬有製薬株式会社 | 抗真菌性物質ｂｅ−３１４０５ |
| ES2203819T3 (es) * | 1996-09-12 | 2004-04-16 | MERCK & CO., INC. | Terapia antifungica combinada. |
-
1995
- 1995-11-06 HU HU9701865A patent/HU218611B/hu not_active IP Right Cessation
- 1995-11-06 CZ CZ962027A patent/CZ202796A3/cs unknown
- 1995-11-06 KR KR1019960703661A patent/KR100391401B1/ko not_active IP Right Cessation
- 1995-11-06 US US08/669,441 patent/US5854280A/en not_active Expired - Fee Related
- 1995-11-06 BR BR9506473A patent/BR9506473A/pt not_active IP Right Cessation
- 1995-11-06 NZ NZ296091A patent/NZ296091A/en unknown
- 1995-11-06 CA CA002179403A patent/CA2179403A1/en not_active Abandoned
- 1995-11-06 ES ES95938406T patent/ES2137549T3/es not_active Expired - Lifetime
- 1995-11-06 PE PE1995283875A patent/PE49696A1/es not_active Application Discontinuation
- 1995-11-06 DK DK95938406T patent/DK0753001T3/da active
- 1995-11-06 ZA ZA959362A patent/ZA959362B/xx unknown
- 1995-11-06 CN CN95192028A patent/CN1056849C/zh not_active Expired - Fee Related
- 1995-11-06 DE DE69512041T patent/DE69512041T2/de not_active Expired - Fee Related
- 1995-11-06 JP JP8515051A patent/JPH09508144A/ja not_active Ceased
- 1995-11-06 EE EE9600117A patent/EE9600117A/xx unknown
- 1995-11-06 AT AT95938406T patent/ATE184284T1/de not_active IP Right Cessation
- 1995-11-06 SI SI9530311T patent/SI0753001T1/xx not_active IP Right Cessation
- 1995-11-06 AU AU39809/95A patent/AU704405B2/en not_active Ceased
- 1995-11-06 AP APAP/P/1996/000824A patent/AP614A/en active
- 1995-11-06 WO PCT/EP1995/004331 patent/WO1996014326A1/en not_active Application Discontinuation
- 1995-11-06 SK SK884-96A patent/SK88496A3/sk unknown
- 1995-11-06 MX MX9602563A patent/MX9602563A/es not_active IP Right Cessation
- 1995-11-06 EP EP95938406A patent/EP0753001B1/en not_active Expired - Lifetime
- 1995-11-06 RU RU96115273/04A patent/RU2152398C1/ru active
- 1995-11-07 IL IL11590595A patent/IL115905A0/xx unknown
- 1995-11-07 AR ARP950100073A patent/AR013815A1/es unknown
- 1995-11-07 CO CO95052481A patent/CO4520226A1/es unknown
- 1995-11-18 TW TW084112259A patent/TW321644B/zh active
-
1996
- 1996-06-10 IS IS4352A patent/IS4352A/is unknown
- 1996-07-03 OA OA60855A patent/OA10303A/en unknown
- 1996-07-05 FI FI962773A patent/FI962773A/fi not_active IP Right Cessation
- 1996-07-05 BG BG100699A patent/BG62620B1/xx unknown
- 1996-07-05 NO NO962856A patent/NO307092B1/no not_active IP Right Cessation
-
1998
- 1998-04-21 HK HK98103335A patent/HK1004222A1/xx not_active IP Right Cessation
- 1998-05-19 US US09/081,090 patent/US5952334A/en not_active Expired - Fee Related
-
1999
- 1999-10-27 GR GR990402767T patent/GR3031677T3/el unknown
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