IL113932A - Temperature sensitive mutant lactose repressor, a gene coding therefor and a method for expressing and controlling the expression of said gene - Google Patents

Temperature sensitive mutant lactose repressor, a gene coding therefor and a method for expressing and controlling the expression of said gene

Info

Publication number
IL113932A
IL113932A IL11393295A IL11393295A IL113932A IL 113932 A IL113932 A IL 113932A IL 11393295 A IL11393295 A IL 11393295A IL 11393295 A IL11393295 A IL 11393295A IL 113932 A IL113932 A IL 113932A
Authority
IL
Israel
Prior art keywords
gene
expression
lactose repressor
expressing
controlling
Prior art date
Application number
IL11393295A
Other languages
English (en)
Other versions
IL113932A0 (en
Original Assignee
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Pharma Co Ltd
Publication of IL113932A0 publication Critical patent/IL113932A0/xx
Publication of IL113932A publication Critical patent/IL113932A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
IL11393295A 1994-06-01 1995-05-31 Temperature sensitive mutant lactose repressor, a gene coding therefor and a method for expressing and controlling the expression of said gene IL113932A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14073694 1994-06-01
JP20031194A JP3723240B2 (ja) 1994-06-01 1994-08-03 遺伝子発現の制御方法

Publications (2)

Publication Number Publication Date
IL113932A0 IL113932A0 (en) 1995-08-31
IL113932A true IL113932A (en) 2005-11-20

Family

ID=26473171

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11393295A IL113932A (en) 1994-06-01 1995-05-31 Temperature sensitive mutant lactose repressor, a gene coding therefor and a method for expressing and controlling the expression of said gene

Country Status (9)

Country Link
US (1) US5622840A (de)
EP (1) EP0685560B1 (de)
JP (1) JP3723240B2 (de)
KR (1) KR100380703B1 (de)
AT (1) ATE391182T1 (de)
DE (1) DE69535739T2 (de)
DK (1) DK0685560T3 (de)
HU (1) HU217580B (de)
IL (1) IL113932A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027108A1 (en) * 1997-11-20 1999-06-03 William Marsh Rice University Lactose repressor proteins with altered ligand responsivity
US7390645B2 (en) 1997-11-20 2008-06-24 William Marsh Rice University Lactose repressor proteins with increased operator DNA binding affinity
AU2002365889A1 (en) * 2001-11-29 2003-06-17 Institutes For Pharmaceutical Discovery, Llc Regulated expression of recombinant dna
WO2004078965A1 (ja) * 2003-03-05 2004-09-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 大腸菌における異種蛋白質の製造方法
CN101287833A (zh) 2005-10-14 2008-10-15 东丽株式会社 酵母和l-乳酸的制造方法
JP5329055B2 (ja) * 2006-07-24 2013-10-30 東レ株式会社 変異型ピルビン酸脱炭酸酵素５遺伝子を有する酵母及び乳酸の製造方法
JP5660167B2 (ja) * 2006-07-24 2015-01-28 東レ株式会社 変異型ピルビン酸脱炭酸酵素５遺伝子を有する酵母及び乳酸の製造方法
WO2013154312A1 (ko) * 2012-04-13 2013-10-17 한국생명공학연구원 Laci 단백질 변이체를 이용한 독성 단백질의 생산 방법
KR101419214B1 (ko) * 2013-01-08 2014-07-14 한국생명공학연구원 LacI 단백질 변이체를 이용한 독성 단백질의 생산 방법
US20140193859A1 (en) * 2013-01-08 2014-07-10 Bertram Jacobs Temperature-dependent insertion of genetic material into genomic DNA
WO2023111304A1 (en) 2021-12-16 2023-06-22 Danmarks Tekniske Universitet Temperature-inducible expression system for thermophilic organisms

Also Published As

Publication number Publication date
JP3723240B2 (ja) 2005-12-07
HUT72398A (en) 1996-04-29
EP0685560A2 (de) 1995-12-06
HU217580B (hu) 2000-02-28
KR100380703B1 (ko) 2003-09-13
US5622840A (en) 1997-04-22
KR960001124A (ko) 1996-01-25
ATE391182T1 (de) 2008-04-15
EP0685560B1 (de) 2008-04-02
EP0685560A3 (de) 1998-01-07
HU9501578D0 (en) 1995-07-28
IL113932A0 (en) 1995-08-31
DE69535739T2 (de) 2009-04-16
JPH0848697A (ja) 1996-02-20
DK0685560T3 (da) 2008-07-14
DE69535739D1 (de) 2008-05-15

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Legal Events

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