DK0685560T3 - Fremgangsmåde til regulering af genekspression - Google Patents

Fremgangsmåde til regulering af genekspression

Info

Publication number
DK0685560T3
DK0685560T3 DK95303708T DK95303708T DK0685560T3 DK 0685560 T3 DK0685560 T3 DK 0685560T3 DK 95303708 T DK95303708 T DK 95303708T DK 95303708 T DK95303708 T DK 95303708T DK 0685560 T3 DK0685560 T3 DK 0685560T3
Authority
DK
Denmark
Prior art keywords
expression
lactose repressor
gene expression
regulating gene
wild
Prior art date
Application number
DK95303708T
Other languages
English (en)
Inventor
Masayuki Yabuta
Kazuhiro Ohsuye
Seiko Miura
Original Assignee
Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asubio Pharma Co Ltd filed Critical Asubio Pharma Co Ltd
Application granted granted Critical
Publication of DK0685560T3 publication Critical patent/DK0685560T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
DK95303708T 1994-06-01 1995-05-31 Fremgangsmåde til regulering af genekspression DK0685560T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14073694 1994-06-01
JP20031194A JP3723240B2 (ja) 1994-06-01 1994-08-03 遺伝子発現の制御方法

Publications (1)

Publication Number Publication Date
DK0685560T3 true DK0685560T3 (da) 2008-07-14

Family

ID=26473171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95303708T DK0685560T3 (da) 1994-06-01 1995-05-31 Fremgangsmåde til regulering af genekspression

Country Status (9)

Country Link
US (1) US5622840A (da)
EP (1) EP0685560B1 (da)
JP (1) JP3723240B2 (da)
KR (1) KR100380703B1 (da)
AT (1) ATE391182T1 (da)
DE (1) DE69535739T2 (da)
DK (1) DK0685560T3 (da)
HU (1) HU217580B (da)
IL (1) IL113932A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027108A1 (en) * 1997-11-20 1999-06-03 William Marsh Rice University Lactose repressor proteins with altered ligand responsivity
US7390645B2 (en) 1997-11-20 2008-06-24 William Marsh Rice University Lactose repressor proteins with increased operator DNA binding affinity
AU2002365889A1 (en) * 2001-11-29 2003-06-17 Institutes For Pharmaceutical Discovery, Llc Regulated expression of recombinant dna
WO2004078965A1 (ja) * 2003-03-05 2004-09-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 大腸菌における異種蛋白質の製造方法
AU2006300688B2 (en) * 2005-10-14 2012-07-19 Toray Industries, Inc. Yeast and method of producing L-lactic acid
JP5660167B2 (ja) * 2006-07-24 2015-01-28 東レ株式会社 変異型ピルビン酸脱炭酸酵素５遺伝子を有する酵母及び乳酸の製造方法
JP5329055B2 (ja) * 2006-07-24 2013-10-30 東レ株式会社 変異型ピルビン酸脱炭酸酵素５遺伝子を有する酵母及び乳酸の製造方法
KR101419214B1 (ko) * 2013-01-08 2014-07-14 한국생명공학연구원 LacI 단백질 변이체를 이용한 독성 단백질의 생산 방법
WO2013154312A1 (ko) * 2012-04-13 2013-10-17 한국생명공학연구원 Laci 단백질 변이체를 이용한 독성 단백질의 생산 방법
US20140193859A1 (en) * 2013-01-08 2014-07-10 Bertram Jacobs Temperature-dependent insertion of genetic material into genomic DNA
WO2023111304A1 (en) 2021-12-16 2023-06-22 Danmarks Tekniske Universitet Temperature-inducible expression system for thermophilic organisms

Also Published As

Publication number Publication date
HU9501578D0 (en) 1995-07-28
DE69535739D1 (de) 2008-05-15
IL113932A (en) 2005-11-20
IL113932A0 (en) 1995-08-31
KR960001124A (ko) 1996-01-25
KR100380703B1 (ko) 2003-09-13
JP3723240B2 (ja) 2005-12-07
EP0685560A2 (en) 1995-12-06
HUT72398A (en) 1996-04-29
EP0685560B1 (en) 2008-04-02
HU217580B (hu) 2000-02-28
EP0685560A3 (en) 1998-01-07
DE69535739T2 (de) 2009-04-16
US5622840A (en) 1997-04-22
ATE391182T1 (de) 2008-04-15
JPH0848697A (ja) 1996-02-20

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