BR0309401A - polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpo - Google Patents
polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpoInfo
- Publication number
- BR0309401A BR0309401A BRPI0309401-4A BR0309401A BR0309401A BR 0309401 A BR0309401 A BR 0309401A BR 0309401 A BR0309401 A BR 0309401A BR 0309401 A BR0309401 A BR 0309401A
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- antibody
- seq
- amino acids
- expression vector
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"POLINUCLEOTìDEO ISOLADO, VETOR DE EXPRESSãO, CéLULA CULTIVADA, MéTODO PARA PRODUZIR POLIPEPTìDEOS, E UM ANTICORPO PARA UM POLIPEPTìDEO, E, ANTICORPO". Divulga-se métodos inéditos para formar um complexo de receptor heterodimérico com IL-28r e CRF2-4. Os métodos podem ser usados para detectar e tratar infecção viral, in vitro e in vivo. Também é possível utilizar polipeptídeos de receptor de ligação de ligando para bloquear atividade de ligando in vitro e in vivo. A presente invenção também inclui métodos de produzir a proteína, usos para a mesma e anticorpos para a mesma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37381302P | 2002-04-19 | 2002-04-19 | |
PCT/US2003/012030 WO2003089603A2 (en) | 2002-04-19 | 2003-04-18 | Cytokine receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0309401A true BR0309401A (pt) | 2007-02-21 |
Family
ID=29251089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0309401-4A BR0309401A (pt) | 2002-04-19 | 2003-04-18 | polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpo |
Country Status (13)
Country | Link |
---|---|
US (7) | US20040029228A1 (pt) |
EP (2) | EP2295455A1 (pt) |
JP (2) | JP4409962B2 (pt) |
CN (2) | CN101676728A (pt) |
AT (1) | ATE493438T1 (pt) |
AU (2) | AU2003225055B2 (pt) |
BR (1) | BR0309401A (pt) |
CA (1) | CA2482368A1 (pt) |
DE (1) | DE60335536D1 (pt) |
ES (1) | ES2356307T3 (pt) |
IL (1) | IL164523A0 (pt) |
RU (1) | RU2004133765A (pt) |
WO (1) | WO2003089603A2 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030027253A1 (en) * | 2000-11-28 | 2003-02-06 | Presnell Scott R. | Cytokine receptor zcytor19 |
TW200300170A (en) * | 2001-11-09 | 2003-05-16 | Wyeth Corp | Type 2 cytokine receptor and nucleic acids encoding same |
WO2003066002A2 (en) | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
CN101676728A (zh) * | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
EP1575609A4 (en) * | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29 |
EP1927600A1 (en) | 2003-08-07 | 2008-06-04 | Zymogenetics, Inc. | Homogeneous preparations of IL-28 and IL-29 |
EP1750749A2 (en) | 2004-04-02 | 2007-02-14 | ZymoGenetics, Inc. | Il-28 and il-29 cysteine mutants for treating viral infection |
CA2574564C (en) * | 2004-07-29 | 2013-04-16 | Zymogenetics, Inc. | Use of il-28 and il-29 to treat cancer and autoimmune disorders |
US20070053933A1 (en) * | 2005-07-20 | 2007-03-08 | Sheppard Paul O | IL28 and IL29 TRUNCATED CYSTEINE MUTANTS AND ANTIVIRAL METHODS OF USING SAME |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
WO2013103981A1 (en) * | 2012-01-06 | 2013-07-11 | Ember Therapeutics, Inc. | Compositions and methods of use of fndc5 polypeptides |
EP2617732A1 (en) * | 2012-01-19 | 2013-07-24 | Vib Vzw | Tools and methods for expression of membrane proteins |
GB201514875D0 (en) * | 2015-08-20 | 2015-10-07 | Autolus Ltd | Receptor |
EP3389677B1 (en) | 2015-12-18 | 2024-06-26 | Sangamo Therapeutics, Inc. | Targeted disruption of the t cell receptor |
Family Cites Families (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US846A (en) | 1838-07-17 | Improvement in revolving fire-arms | ||
US5738A (en) | 1848-08-29 | Francis kelsey | ||
IE54046B1 (en) | 1981-08-25 | 1989-05-24 | Celltech Ltd | Expression vectors |
US4579821A (en) | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
US4486533A (en) | 1982-09-02 | 1984-12-04 | St. Louis University | Filamentous fungi functional replicating extrachromosomal element |
US4599311A (en) | 1982-08-13 | 1986-07-08 | Kawasaki Glenn H | Glycolytic promotersfor regulated protein expression: protease inhibitor |
US4977092A (en) | 1985-06-26 | 1990-12-11 | Amgen | Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells |
US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
US4713339A (en) | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
US5139936A (en) | 1983-02-28 | 1992-08-18 | Collaborative Research, Inc. | Use of the GAL1 yeast promoter |
US4661454A (en) | 1983-02-28 | 1987-04-28 | Collaborative Research, Inc. | GAL1 yeast promoter linked to non galactokinase gene |
US4624846A (en) | 1983-07-29 | 1986-11-25 | Immunomedics, Inc. | Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles |
US4870008A (en) | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
US4931373A (en) | 1984-05-25 | 1990-06-05 | Zymogenetics, Inc. | Stable DNA constructs for expression of α-1 antitrypsin |
US4766073A (en) | 1985-02-25 | 1988-08-23 | Zymogenetics Inc. | Expression of biologically active PDGF analogs in eucaryotic cells |
DE3578435D1 (de) | 1984-12-06 | 1990-08-02 | Labofina Sa | Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
GR860984B (en) | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
US4882279A (en) | 1985-10-25 | 1989-11-21 | Phillips Petroleum Company | Site selective genomic modification of yeast of the genus pichia |
US4935349A (en) | 1986-01-17 | 1990-06-19 | Zymogenetics, Inc. | Expression of higher eucaryotic genes in aspergillus |
US5057313A (en) | 1986-02-25 | 1991-10-15 | The Center For Molecular Medicine And Immunology | Diagnostic and therapeutic antibody conjugates |
GB8611832D0 (en) | 1986-05-15 | 1986-06-25 | Holland I B | Polypeptide |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5055291A (en) | 1986-11-04 | 1991-10-08 | Baylor College Of Medicine | Compositions for preventing secondary cataracts |
US5063154A (en) | 1987-06-24 | 1991-11-05 | Whitehead Institute For Biomedical Research | Pheromone - inducible yeast promoter |
EP0325224B1 (en) | 1988-01-22 | 1996-07-31 | ZymoGenetics, Inc. | Methods of producing secreted receptor analogs |
US5567584A (en) | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
US5529932A (en) | 1988-01-28 | 1996-06-25 | Pharmacia, S.P.A. | Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis |
US5120525A (en) | 1988-03-29 | 1992-06-09 | Immunomedics, Inc. | Radiolabeled antibody cytotoxic therapy of cancer |
US4956288A (en) | 1988-04-22 | 1990-09-11 | Biogen, Inc. | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA |
US5037743A (en) | 1988-08-05 | 1991-08-06 | Zymogenetics, Inc. | BAR1 secretion signal |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5162228A (en) | 1988-12-28 | 1992-11-10 | Takeda Chemical Industries, Ltd. | Gylceraldehyde-3-phosphate dehydrogenase gene and promoter |
US5576288A (en) | 1989-04-27 | 1996-11-19 | The Salk Institute For Biological Studies | Fibroblast growth factor conjugates |
US5191067A (en) | 1989-04-27 | 1993-03-02 | The Salk Institute For Biological Studies | Fibroblast growth factor conjugates |
US5162222A (en) | 1989-07-07 | 1992-11-10 | Guarino Linda A | Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells or recombinant baculoviruses |
US5635384A (en) | 1990-06-11 | 1997-06-03 | Dowelanco | Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using |
US5478804A (en) | 1990-09-19 | 1995-12-26 | The Salk Institute For Biological Studies | Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates |
IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
JPH06504438A (ja) | 1990-12-13 | 1994-05-26 | イミュネックス・コーポレーション | 白血病抑制因子受容体 |
US5298418A (en) | 1991-09-16 | 1994-03-29 | Boyce Thompson Institute For Plant Research, Inc. | Cell line isolated from larval midgut tissue of Trichoplusia ni |
US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
CA2144651A1 (en) | 1992-09-14 | 1994-03-31 | Timothy J. Miller | Immortalized cells and uses therefor |
AU6208494A (en) | 1993-03-02 | 1994-09-26 | Universidad De Valladolid | Non-toxic ribosome inactivating proteins (rips) with two chains, process for the preparation thereof and applications |
EP0717753B1 (en) | 1993-09-06 | 1998-12-02 | Menarini Ricerche S.p.A. | Ribosome inactivating proteins extracted from seeds of saponaria ocymoides and vaccaria pyramidata, their preparation and immunotoxins containing them |
US5443953A (en) | 1993-12-08 | 1995-08-22 | Immunomedics, Inc. | Preparation and use of immunoconjugates |
AU700185B2 (en) | 1994-02-14 | 1998-12-24 | Zymogenetics Inc. | Method for preparing orphan receptor ligands |
US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US5911995A (en) | 1994-08-19 | 1999-06-15 | Regents Of The University Of Minnesota | EGF-genistein conjugates for the treatment of cancer |
US5738846A (en) | 1994-11-10 | 1998-04-14 | Enzon, Inc. | Interferon polymer conjugates and process for preparing the same |
EP0889966A1 (en) | 1995-11-09 | 1999-01-13 | ZymoGenetics, Inc. | Compositions and methods for producing heterologous polypeptides in pichia methanolica |
IT1286663B1 (it) | 1996-06-27 | 1998-07-15 | Ministero Uni Ricerca Scient E | Proteina capace di inibire l'attivita' ribosomiale,sua preparazione ed uso come immunoconiugato chimico o ricombinante e sequenza di cdna |
WO1998002565A1 (en) | 1996-07-17 | 1998-01-22 | Zymogenetics, Inc. | TRANSFORMATION OF $i(PICHIA METHANOLICA) |
IL128072A0 (en) | 1996-07-17 | 1999-11-30 | Zymogenetics Inc | Preparation of pichia methanolica auxotrophic mutants |
KR20080059467A (ko) | 1996-12-03 | 2008-06-27 | 아브게닉스, 인크. | 복수의 vh 및 vk 부위를 함유하는 사람 면역글로불린유전자좌를 갖는 형질전환된 포유류 및 이로부터 생성된항체 |
US5945511A (en) | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
AU8040898A (en) | 1997-06-06 | 1998-12-21 | Tanox Pharma B.V. | Type-1 ribosome-inactivating protein |
US5965704A (en) | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
CN1238367C (zh) | 1998-10-26 | 2006-01-25 | 路德维格癌症研究院 | 分离的编码t细胞诱导因子(tif)的核酸分子,其编码蛋白及其应用 |
AU6069300A (en) | 1999-07-02 | 2001-01-22 | Chiron Corporation | Novel human genes and gene expression products |
EP1294888B1 (en) | 2000-06-30 | 2007-04-25 | ZymoGenetics, Inc. | Interferon-like protein zcyto21 |
DE10031389A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
EP2298789B1 (en) * | 2000-09-08 | 2012-03-14 | Schering Corporation | Mammalian genes; related reagents and methods |
US20030027253A1 (en) * | 2000-11-28 | 2003-02-06 | Presnell Scott R. | Cytokine receptor zcytor19 |
CN101531715A (zh) * | 2001-04-20 | 2009-09-16 | 津莫吉尼蒂克斯公司 | 细胞因子蛋白质家族 |
JPWO2003031620A1 (ja) | 2001-10-02 | 2005-01-27 | 持田製薬株式会社 | 新規クラスiiサイトカイン受容体 |
TW200300170A (en) * | 2001-11-09 | 2003-05-16 | Wyeth Corp | Type 2 cytokine receptor and nucleic acids encoding same |
US7033787B2 (en) * | 2001-12-21 | 2006-04-25 | Ludwig Institute For Cancer Research | Isolated cytokine receptor LICR-2 |
WO2003066002A2 (en) | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
CN101676728A (zh) * | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
EP1575609A4 (en) * | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | METHOD FOR THE TREATMENT OF VIRUS INFECTIONS USING IL-28 AND IL-29 |
CA2516128A1 (en) * | 2003-02-14 | 2004-09-02 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
-
2003
- 2003-04-18 CN CN200910175119A patent/CN101676728A/zh active Pending
- 2003-04-18 EP EP10180287A patent/EP2295455A1/en not_active Withdrawn
- 2003-04-18 WO PCT/US2003/012030 patent/WO2003089603A2/en active Application Filing
- 2003-04-18 DE DE60335536T patent/DE60335536D1/de not_active Expired - Lifetime
- 2003-04-18 CA CA002482368A patent/CA2482368A1/en not_active Abandoned
- 2003-04-18 BR BRPI0309401-4A patent/BR0309401A/pt unknown
- 2003-04-18 CN CN03812713.XA patent/CN1659274A/zh active Pending
- 2003-04-18 ES ES03721762T patent/ES2356307T3/es not_active Expired - Lifetime
- 2003-04-18 RU RU2004133765/13A patent/RU2004133765A/ru not_active Application Discontinuation
- 2003-04-18 AU AU2003225055A patent/AU2003225055B2/en not_active Ceased
- 2003-04-18 EP EP03721762A patent/EP1497415B1/en not_active Expired - Lifetime
- 2003-04-18 US US10/420,034 patent/US20040029228A1/en not_active Abandoned
- 2003-04-18 AT AT03721762T patent/ATE493438T1/de not_active IP Right Cessation
- 2003-04-18 JP JP2003586316A patent/JP4409962B2/ja not_active Expired - Fee Related
-
2004
- 2004-10-12 IL IL16452304A patent/IL164523A0/xx unknown
-
2006
- 2006-10-09 US US11/539,816 patent/US20070134727A1/en not_active Abandoned
- 2006-10-09 US US11/539,780 patent/US7723298B2/en not_active Expired - Lifetime
- 2006-10-09 US US11/539,789 patent/US20070264685A1/en not_active Abandoned
- 2006-10-09 US US11/539,841 patent/US20070048847A1/en not_active Abandoned
-
2009
- 2009-07-23 AU AU2009203007A patent/AU2009203007A1/en not_active Abandoned
- 2009-07-24 JP JP2009172922A patent/JP2009268469A/ja not_active Ceased
-
2010
- 2010-03-12 US US12/723,364 patent/US20110171627A1/en not_active Abandoned
-
2011
- 2011-10-04 US US13/252,723 patent/US20120053321A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2356307T3 (es) | 2011-04-06 |
JP2009268469A (ja) | 2009-11-19 |
EP1497415B1 (en) | 2010-12-29 |
US20040029228A1 (en) | 2004-02-12 |
WO2003089603A2 (en) | 2003-10-30 |
AU2003225055A1 (en) | 2003-11-03 |
US20120053321A1 (en) | 2012-03-01 |
CN1659274A (zh) | 2005-08-24 |
WO2003089603A3 (en) | 2004-09-16 |
IL164523A0 (en) | 2005-12-18 |
DE60335536D1 (de) | 2011-02-10 |
RU2004133765A (ru) | 2005-06-27 |
AU2003225055B2 (en) | 2009-04-23 |
CN101676728A (zh) | 2010-03-24 |
US20070264685A1 (en) | 2007-11-15 |
EP2295455A1 (en) | 2011-03-16 |
JP2006504401A (ja) | 2006-02-09 |
US20110171627A1 (en) | 2011-07-14 |
CA2482368A1 (en) | 2003-10-30 |
JP4409962B2 (ja) | 2010-02-03 |
US20070134727A1 (en) | 2007-06-14 |
US20070048847A1 (en) | 2007-03-01 |
US7723298B2 (en) | 2010-05-25 |
US20070122879A1 (en) | 2007-05-31 |
AU2009203007A1 (en) | 2009-08-13 |
EP1497415A2 (en) | 2005-01-19 |
ATE493438T1 (de) | 2011-01-15 |
EP1497415A4 (en) | 2006-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0309401A (pt) | polinucleotìdeo isolado, vetor de expressão, célula cultivada, método para produzir polipeptìdeos, e um anticorpo para um polipeptìdeo, e, anticorpo | |
DE69331550D1 (de) | Klonierung und expression von biologisch aktiver alpha-galaktosidase a | |
RU2004126135A (ru) | Новый цитокин zalpha11-лиганд | |
DK1422237T3 (da) | Fremgangsmåder til rekombinant frembringelse af antifusogene peptider | |
DK1305437T3 (da) | Ekspression af biologisk aktive polypeptider i andemad | |
NO20015587D0 (no) | Ekspresjon og eksport av interferon-<alfa> proteiner som Fc- fusjonsproteiner | |
BG101408A (en) | Analogs of keratinocyte growth factor | |
BR0306979A (pt) | Polipeptìdeo isolado, proteìna de fusão, molécula isolada de polinucleotìdeo, vetor de expressão, célula cultivada, anticorpo ou fragmento de anticorpo, e, métodos para produzir uma proteìna, para produzir um anticorpo, para estimular uma resposta imune em um mamìfero, para expandir células hematopoiéticas e progenitores de células hematopoiéticas, para detectar a presença de rna zcytor17lig e de zcytor17lig em uma amostra biológica, para matar cérlulas cancerìgenas, para inibir a proliferação induzida por zcytor17lig ou diferenciação de células hematopoiéticas e progenitoras de células hematopoiéticas, para reduzir a inflamação induzida por zcytor17lig para suprimir uma resposta inflamatória em um mamìfero com inflamação, para tratar um mamìfero acometido por uma doença inflamatória e para detectar inflamação em um paciente | |
DK0953644T3 (da) | Systemer til masseproduktion af proteiner eller peptider ved mikroorganismer af slægten Humicola | |
KR910006483A (ko) | 재조합 아프로티닌 변이체, 균질하게 프로세싱된 아프로티닌 변이체의 미생물을 이용한 유전공학적 제조 방법 및 그의 치료 용도 | |
DK326289A (da) | Fremgangsmaade til fremstilling af et protein ud fra gaersvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmaaden | |
EP1728859A4 (en) | SEQUENCE CAPABLE OF ACCELERATING GENE EXPRESSION AT A MODERATELY LOW TEMPERATURE | |
ES2088911T3 (es) | Gen de la proteasa i de achromobacter y el producto de este gen. | |
DE69737007D1 (de) | Protein-disulfidisomerase-Gen eines methylotrophen Hefestammes | |
EP0750040A3 (en) | Macrophage stimulating protein variant and method for producing the same | |
AU4765099A (en) | Method of genetic modification of a wild type viral sequence | |
DE59814427D1 (de) | Immunreaktive Bereiche des Glycoproteins gpII des Varicella Zoster-Virus (VZV) | |
WO2003054010A3 (en) | Early stage redox-related apoptosis modulator-2 (esram-2) | |
KR950000882A (ko) | 한국형 씨(c)형 간염 바이러스의 초변화 영역의 뉴클레오티드 서열 및 아미노산 서열 | |
JO2429B1 (en) | Ways to produce recombinant peptides of antigen - merger | |
KR970062029A (ko) | 수두 바이러스의 당단백질을 대량발현시키는 동물세포주 | |
DK0959130T3 (da) | Kloning og udtrykkelse af nyt glucoamylasegen fra Endomyces fibuliger | |
WO2003048361A3 (en) | P55pik |