IL112323A - Process and intermediates for the preparation of salts of acid 7 - (1a, 5b, 6a) - (6 - amino - 3 azabicyclo [0.1.3] - hex - 3yl) - 1 - (2, 4 - difluorophenyl) - 6 - fluorine - 4,1 - Dihydro - 4 - Oxo - 1,8 - Naphthiridine - 3 - Carboxylate - Google Patents

Process and intermediates for the preparation of salts of acid 7 - (1a, 5b, 6a) - (6 - amino - 3 azabicyclo [0.1.3] - hex - 3yl) - 1 - (2, 4 - difluorophenyl) - 6 - fluorine - 4,1 - Dihydro - 4 - Oxo - 1,8 - Naphthiridine - 3 - Carboxylate

Info

Publication number
IL112323A
IL112323A IL11232395A IL11232395A IL112323A IL 112323 A IL112323 A IL 112323A IL 11232395 A IL11232395 A IL 11232395A IL 11232395 A IL11232395 A IL 11232395A IL 112323 A IL112323 A IL 112323A
Authority
IL
Israel
Prior art keywords
compound
formula
alkyl
acid
treating
Prior art date
Application number
IL11232395A
Other languages
English (en)
Hebrew (he)
Other versions
IL112323A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL112323A0 publication Critical patent/IL112323A0/xx
Publication of IL112323A publication Critical patent/IL112323A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11232395A 1994-01-18 1995-01-12 Process and intermediates for the preparation of salts of acid 7 - (1a, 5b, 6a) - (6 - amino - 3 azabicyclo [0.1.3] - hex - 3yl) - 1 - (2, 4 - difluorophenyl) - 6 - fluorine - 4,1 - Dihydro - 4 - Oxo - 1,8 - Naphthiridine - 3 - Carboxylate IL112323A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18194294A 1994-01-18 1994-01-18

Publications (2)

Publication Number Publication Date
IL112323A0 IL112323A0 (en) 1995-03-30
IL112323A true IL112323A (en) 2001-03-19

Family

ID=22666458

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11232395A IL112323A (en) 1994-01-18 1995-01-12 Process and intermediates for the preparation of salts of acid 7 - (1a, 5b, 6a) - (6 - amino - 3 azabicyclo [0.1.3] - hex - 3yl) - 1 - (2, 4 - difluorophenyl) - 6 - fluorine - 4,1 - Dihydro - 4 - Oxo - 1,8 - Naphthiridine - 3 - Carboxylate

Country Status (19)

Country Link
EP (1) EP0740667A1 (ja)
JP (1) JP2891543B2 (ja)
KR (1) KR100221386B1 (ja)
CN (1) CN1141634A (ja)
AU (1) AU694149B2 (ja)
BR (1) BR9408490A (ja)
CA (1) CA2181351C (ja)
CZ (1) CZ286896B6 (ja)
FI (1) FI962880A (ja)
HU (1) HUT74883A (ja)
IL (1) IL112323A (ja)
MY (1) MY130510A (ja)
NO (1) NO305838B1 (ja)
NZ (1) NZ276478A (ja)
PL (1) PL179996B1 (ja)
RU (1) RU2147303C1 (ja)
TW (1) TW414791B (ja)
WO (1) WO1995019361A1 (ja)
ZA (1) ZA95340B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK280535B6 (sk) * 1995-06-06 2000-03-13 Pfizer Inc. Kryštalická forma bezvodej soli kyseliny 7-([1a,5a
ES2095809B1 (es) * 1995-07-27 1997-12-16 Sint Quimica Sa Procedimiento para la preparacion de acidos naftiridin carboxilicos y sus sales.
GB9524466D0 (en) * 1995-11-30 1996-01-31 Pfizer Ltd Process
GB9614422D0 (en) * 1996-07-09 1996-09-04 Pfizer Ltd Novel process
JPH1087617A (ja) * 1996-07-09 1998-04-07 Pfizer Inc キノリン系抗生物質の合成に有用な中間体の製法
HN1998000106A (es) 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
HN1999000141A (es) * 1998-09-03 2000-06-19 Pfizer Prod Inc Procedimiento para preparar sales de trovafloxacina de adicion de acidos.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids

Also Published As

Publication number Publication date
CZ286896B6 (en) 2000-07-12
PL179996B1 (en) 2000-11-30
NO962990D0 (no) 1996-07-17
PL317043A1 (en) 1997-03-03
MY130510A (en) 2007-06-29
KR100221386B1 (ko) 1999-09-15
JPH09501182A (ja) 1997-02-04
WO1995019361A1 (en) 1995-07-20
HUT74883A (en) 1997-02-28
BR9408490A (pt) 1997-08-26
EP0740667A1 (en) 1996-11-06
FI962880A0 (fi) 1996-07-17
HU9601957D0 (en) 1996-09-30
NZ276478A (en) 1998-05-27
TW414791B (en) 2000-12-11
CN1141634A (zh) 1997-01-29
AU1075495A (en) 1995-08-01
JP2891543B2 (ja) 1999-05-17
CA2181351A1 (en) 1995-07-20
CZ211196A3 (en) 1997-01-15
AU694149B2 (en) 1998-07-16
NO305838B1 (no) 1999-08-02
IL112323A0 (en) 1995-03-30
RU2147303C1 (ru) 2000-04-10
NO962990L (no) 1996-07-17
CA2181351C (en) 1999-09-28
ZA95340B (en) 1996-07-17
FI962880A (fi) 1996-07-17

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees