MY130510A - Process and intermediates for preparing naphthyridonecarboxylic acid salts - Google Patents
Process and intermediates for preparing naphthyridonecarboxylic acid saltsInfo
- Publication number
- MY130510A MY130510A MYPI95000103A MYPI9500103A MY130510A MY 130510 A MY130510 A MY 130510A MY PI95000103 A MYPI95000103 A MY PI95000103A MY PI9500103 A MYPI9500103 A MY PI9500103A MY 130510 A MY130510 A MY 130510A
- Authority
- MY
- Malaysia
- Prior art keywords
- intermediates
- preparing
- acid salts
- naphthyridonecarboxylic acid
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
THE INVENTION RELATES TO NOVEL PROCESS FOR PREPARING COMPOUNDS OF THE FORMULA WHEREIN R1H IS AS DEFINED BELOW, WHICH IS A SALT OF THE NAPHTHYRIDONE ANTIBIOTIC 7-(1A,5A,6A)-(6-AMINO-3-AZABICYCLO[3.1.0]HEX-3-YL)-1-(2,4-DIFLUOROPHENYL)-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID AND A PHARMACEUTICALLY ACCEPTABLE ACID. THE SALT AND ANTIBIOTICS HAVE ANTIBACTERIAL ACTIVITY. THIS INVENTION ALSO RELATES TO NOVEL INTERMEDIATES, AND PROCESSES FOR THEIR PREPARATION, OF THE FORMULAE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18194294A | 1994-01-18 | 1994-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY130510A true MY130510A (en) | 2007-06-29 |
Family
ID=22666458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI95000103A MY130510A (en) | 1994-01-18 | 1995-01-17 | Process and intermediates for preparing naphthyridonecarboxylic acid salts |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0740667A1 (en) |
| JP (1) | JP2891543B2 (en) |
| KR (1) | KR100221386B1 (en) |
| CN (1) | CN1141634A (en) |
| AU (1) | AU694149B2 (en) |
| BR (1) | BR9408490A (en) |
| CA (1) | CA2181351C (en) |
| CZ (1) | CZ286896B6 (en) |
| FI (1) | FI962880A0 (en) |
| HU (1) | HUT74883A (en) |
| IL (1) | IL112323A (en) |
| MY (1) | MY130510A (en) |
| NO (1) | NO305838B1 (en) |
| NZ (1) | NZ276478A (en) |
| PL (1) | PL179996B1 (en) |
| RU (1) | RU2147303C1 (en) |
| TW (1) | TW414791B (en) |
| WO (1) | WO1995019361A1 (en) |
| ZA (1) | ZA95340B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK280535B6 (en) * | 1995-06-06 | 2000-03-13 | Pfizer Inc. | Crystal form of anhydrous 7-([1 alpha,5 alpha,6 alpha]-6-amino- -3-azabicyclo[3.1.0]hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)- -1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt, a method of its preparation, pharmaceutical agents based thereon, and the use of this form |
| ES2095809B1 (en) * | 1995-07-27 | 1997-12-16 | Sint Quimica Sa | PROCEDURE FOR THE PREPARATION OF NAFTIRIDIN CARBOXYLIC ACIDS AND THEIR SALTS. |
| GB9524466D0 (en) * | 1995-11-30 | 1996-01-31 | Pfizer Ltd | Process |
| GB9614422D0 (en) * | 1996-07-09 | 1996-09-04 | Pfizer Ltd | Novel process |
| JPH1087617A (en) * | 1996-07-09 | 1998-04-07 | Pfizer Inc | Production of intermediate useful for synthesizing quinoline-based antibiotic |
| HN1998000106A (en) | 1997-08-01 | 1999-01-08 | Pfizer Prod Inc | PARENTERAL COMPOSITIONS OF ALATROFLAXACINO |
| HN1999000141A (en) * | 1998-09-03 | 2000-06-19 | Pfizer Prod Inc | PROCEDURE FOR PREPARING SALTS OF TROVAFLOXACIN FOR ADDITION OF ACIDS. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164402A (en) * | 1989-08-16 | 1992-11-17 | Pfizer Inc | Azabicyclo quinolone and naphthyridinone carboxylic acids |
-
1994
- 1994-12-12 WO PCT/IB1994/000410 patent/WO1995019361A1/en not_active Application Discontinuation
- 1994-12-12 KR KR1019960703846A patent/KR100221386B1/en not_active IP Right Cessation
- 1994-12-12 EP EP95901569A patent/EP0740667A1/en not_active Withdrawn
- 1994-12-12 PL PL94317043A patent/PL179996B1/en unknown
- 1994-12-12 BR BR9408490A patent/BR9408490A/en not_active Application Discontinuation
- 1994-12-12 HU HU9601957A patent/HUT74883A/en unknown
- 1994-12-12 JP JP7518931A patent/JP2891543B2/en not_active Expired - Lifetime
- 1994-12-12 CZ CZ19962111A patent/CZ286896B6/en not_active IP Right Cessation
- 1994-12-12 RU RU96115919A patent/RU2147303C1/en active
- 1994-12-12 CN CN94194842A patent/CN1141634A/en active Pending
- 1994-12-12 CA CA002181351A patent/CA2181351C/en not_active Expired - Fee Related
- 1994-12-12 NZ NZ276478A patent/NZ276478A/en unknown
- 1994-12-12 AU AU10754/95A patent/AU694149B2/en not_active Ceased
- 1994-12-17 TW TW083111804A patent/TW414791B/en not_active IP Right Cessation
-
1995
- 1995-01-12 IL IL11232395A patent/IL112323A/en not_active IP Right Cessation
- 1995-01-17 ZA ZA95340A patent/ZA95340B/en unknown
- 1995-01-17 MY MYPI95000103A patent/MY130510A/en unknown
-
1996
- 1996-07-17 FI FI962880A patent/FI962880A0/en unknown
- 1996-07-17 NO NO962990A patent/NO305838B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0740667A1 (en) | 1996-11-06 |
| CZ211196A3 (en) | 1997-01-15 |
| CN1141634A (en) | 1997-01-29 |
| NO962990D0 (en) | 1996-07-17 |
| KR100221386B1 (en) | 1999-09-15 |
| IL112323A0 (en) | 1995-03-30 |
| JPH09501182A (en) | 1997-02-04 |
| AU1075495A (en) | 1995-08-01 |
| JP2891543B2 (en) | 1999-05-17 |
| AU694149B2 (en) | 1998-07-16 |
| NO305838B1 (en) | 1999-08-02 |
| BR9408490A (en) | 1997-08-26 |
| CA2181351C (en) | 1999-09-28 |
| NO962990L (en) | 1996-07-17 |
| NZ276478A (en) | 1998-05-27 |
| PL317043A1 (en) | 1997-03-03 |
| WO1995019361A1 (en) | 1995-07-20 |
| FI962880A (en) | 1996-07-17 |
| PL179996B1 (en) | 2000-11-30 |
| RU2147303C1 (en) | 2000-04-10 |
| TW414791B (en) | 2000-12-11 |
| HU9601957D0 (en) | 1996-09-30 |
| FI962880A0 (en) | 1996-07-17 |
| IL112323A (en) | 2001-03-19 |
| ZA95340B (en) | 1996-07-17 |
| HUT74883A (en) | 1997-02-28 |
| CZ286896B6 (en) | 2000-07-12 |
| CA2181351A1 (en) | 1995-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AP9600817A0 (en) | Novel cryatal form of anhydrous 7-( [1A,5A,6A]-6-amino3-3-azabicyclo [3.1.0.] hex-3-yl) -6-fluro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt. | |
| AU666772B2 (en) | Quinolone carboxylic acids | |
| IE883900L (en) | Antibacterial agents | |
| CA2209487A1 (en) | Imidazo[4,5-c]quinoline amines | |
| PT85411A (en) | 7-]]3-(aminomethyl)-3-alkyl"-1-pyrrolidinyl"-quinoline-carboxylic acids | |
| EP1846417A1 (en) | Antibacterial agents | |
| CA2223404A1 (en) | Novel crystal form of anhydrous 7-(¬1.alpha., 5.alpha., 6.alpha.|-6-amino-3-azabicyclo¬3.1.0|hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt | |
| MY130510A (en) | Process and intermediates for preparing naphthyridonecarboxylic acid salts | |
| KR100531967B1 (en) | Tricyclic amine derivatives, an antimicrobial agent comprising the compound and a process for preparing a quinolone compound | |
| RU2042677C1 (en) | Derivatives of 1,8-benzo-[b]-naphthiridine or their salts with metals, nitrogen bases or acids, or their hydrates showing antibacterial activity | |
| EP0393424A3 (en) | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | |
| KR0136792B1 (en) | Method for their preparation and antibacterial agents containing them | |
| DE4234330A1 (en) | Quinolonecarboxylic acids | |
| IE61722B1 (en) | Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino)-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents | |
| HUT38344A (en) | Process for preparing pyrazolo/3,4-b/pyridine amides | |
| CA2344439A1 (en) | Process for the production of a naphthyridine carboxylic acid derivative (methanesulfonate sesquihydrate) | |
| IL103271A (en) | 8-azetidino-7-fluoro-1,4-dihydro-4-oxo-benzo (1,8) naphthyridine-3-carboxylic acid derivatives their preparation and compositions containing them | |
| EP0287116A3 (en) | Thiadiazolylacetamide cephem derivatives | |
| SK137194A3 (en) | 1-(2-fluorinecyclopropyl)-quinoline-carboxylic) and 1-(2- -florinecyclopropyl)-naphthyridonecarboxylic acid derivatives, method of their producing and their using in medicines | |
| CA2155153A1 (en) | Quinolone- and naphthyridonecarboxylic acid derivatives | |
| PT84005A (en) | 6h-isoxazol]3,4-d"pyrazolo]3,4-b"pyridines a process and intermediates for their preparation and their use as medicaments |