IL111395A - 5-(Arylisoxazole-4-yl)-substituted 2-amino carboxylic acid compounds and pharmaceutical compositions containing them - Google Patents

5-(Arylisoxazole-4-yl)-substituted 2-amino carboxylic acid compounds and pharmaceutical compositions containing them

Info

Publication number
IL111395A
IL111395A IL11139594A IL11139594A IL111395A IL 111395 A IL111395 A IL 111395A IL 11139594 A IL11139594 A IL 11139594A IL 11139594 A IL11139594 A IL 11139594A IL 111395 A IL111395 A IL 111395A
Authority
IL
Israel
Prior art keywords
arylisoxazole
substituted
carboxylic acid
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11139594A
Other languages
English (en)
Other versions
IL111395A0 (en
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of IL111395A0 publication Critical patent/IL111395A0/xx
Publication of IL111395A publication Critical patent/IL111395A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Sewing Machines And Sewing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyurethanes Or Polyureas (AREA)
IL11139594A 1993-11-01 1994-10-25 5-(Arylisoxazole-4-yl)-substituted 2-amino carboxylic acid compounds and pharmaceutical compositions containing them IL111395A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK931234A DK123493D0 (da) 1993-11-01 1993-11-01 Compounds

Publications (2)

Publication Number Publication Date
IL111395A0 IL111395A0 (en) 1994-12-29
IL111395A true IL111395A (en) 1999-06-20

Family

ID=8102507

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11139494A IL111394A (en) 1993-11-01 1994-10-25 Phenyl indole compounds and a pharmaceutical mixture containing them
IL11139594A IL111395A (en) 1993-11-01 1994-10-25 5-(Arylisoxazole-4-yl)-substituted 2-amino carboxylic acid compounds and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL11139494A IL111394A (en) 1993-11-01 1994-10-25 Phenyl indole compounds and a pharmaceutical mixture containing them

Country Status (27)

Country Link
US (1) US5703087A (no)
EP (1) EP0726898B1 (no)
JP (1) JP3898219B2 (no)
KR (1) KR100350550B1 (no)
CN (1) CN1134149A (no)
AT (1) ATE198199T1 (no)
AU (1) AU683700B2 (no)
CA (1) CA2175498C (no)
CZ (1) CZ291403B6 (no)
DE (1) DE69426462T2 (no)
DK (2) DK123493D0 (no)
ES (1) ES2154303T3 (no)
FI (1) FI116623B (no)
GR (1) GR3035462T3 (no)
HK (1) HK1013817A1 (no)
HU (1) HUT76063A (no)
IL (2) IL111394A (no)
LV (1) LV12805B (no)
NO (1) NO309038B1 (no)
NZ (1) NZ275086A (no)
PL (1) PL176391B1 (no)
PT (1) PT726898E (no)
RU (1) RU2156249C2 (no)
SI (1) SI0726898T1 (no)
SK (1) SK281761B6 (no)
WO (1) WO1995012591A1 (no)
ZA (1) ZA948589B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489341B1 (en) 1999-06-02 2002-12-03 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
WO2001021614A1 (en) * 1999-09-09 2001-03-29 H. Lundbeck A/S 5-aminoalkyl and 5-aminocarbonyl substituted indoles
US20070212412A1 (en) * 2005-09-08 2007-09-13 H. Lundbeck A/S Stable solid formulation of sertindole
TW200821296A (en) * 2006-06-01 2008-05-16 Lundbeck & Co As H Use of sertindole for the preventive treatment of suicidal behaviour
CA2781685C (en) * 2009-12-11 2018-09-04 Autifony Therapeutics Limited Imidazolidinedione derivatives
JP5860042B2 (ja) * 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
EP2649066B1 (en) 2010-12-06 2015-10-21 Autifony Therapeutics Limited Hydantoin derivatives useful as kv3 inhibitors
CN103596943B (zh) * 2011-06-07 2016-10-12 奥蒂福尼疗法有限公司 用作kv3抑制剂的乙内酰脲衍生物
PL2788339T3 (pl) * 2011-12-06 2016-09-30 Pochodne hydantoiny przydatne jako inhibitory KV3
US9669030B2 (en) 2012-05-22 2017-06-06 Autifony Therapeutics Limited Hydantoin derivatives as Kv3 inhibitors
EP2852589B1 (en) 2012-05-22 2021-04-28 Autifony Therapeutics Limited Triazoles as kv3 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
GB8908085D0 (en) * 1989-04-11 1989-05-24 Lundbeck & Co As H New therapeutic use
DK152090D0 (da) * 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater

Also Published As

Publication number Publication date
IL111394A (en) 1998-08-16
CA2175498C (en) 2005-07-26
HK1013817A1 (en) 1999-09-10
SI0726898T1 (en) 2001-04-30
NZ275086A (en) 1997-10-24
FI116623B (fi) 2006-01-13
ES2154303T3 (es) 2001-04-01
DK123493D0 (da) 1993-11-01
CZ124896A3 (en) 1996-09-11
EP0726898A1 (en) 1996-08-21
DK0726898T3 (da) 2001-04-30
DE69426462T2 (de) 2001-04-26
ATE198199T1 (de) 2001-01-15
JP3898219B2 (ja) 2007-03-28
JPH09506083A (ja) 1997-06-17
CZ291403B6 (cs) 2003-03-12
LV12805B (lv) 2002-05-20
US5703087A (en) 1997-12-30
GR3035462T3 (en) 2001-05-31
FI961844A0 (fi) 1996-04-30
HU9601144D0 (en) 1996-07-29
PL176391B1 (pl) 1999-05-31
WO1995012591A1 (en) 1995-05-11
NO961746D0 (no) 1996-04-30
CA2175498A1 (en) 1995-05-11
ZA948589B (en) 1995-06-26
SK281761B6 (sk) 2001-07-10
KR960705814A (ko) 1996-11-08
PL314181A1 (en) 1996-08-19
IL111394A0 (en) 1994-12-29
CN1134149A (zh) 1996-10-23
PT726898E (pt) 2001-05-31
IL111395A0 (en) 1994-12-29
DE69426462D1 (de) 2001-01-25
AU683700B2 (en) 1997-11-20
NO961746L (no) 1996-06-28
HUT76063A (en) 1997-06-30
EP0726898B1 (en) 2000-12-20
NO309038B1 (no) 2000-12-04
RU2156249C2 (ru) 2000-09-20
AU8057794A (en) 1995-05-23
LV12805A (en) 2002-03-20
KR100350550B1 (ko) 2002-12-12
FI961844A (fi) 1996-04-30
SK53496A3 (en) 1996-11-06

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void