IL108031A0 - Difluoro pentapeptide derivatives and pharmaceutical compositions containing them - Google Patents

Difluoro pentapeptide derivatives and pharmaceutical compositions containing them

Info

Publication number
IL108031A0
IL108031A0 IL10803193A IL10803193A IL108031A0 IL 108031 A0 IL108031 A0 IL 108031A0 IL 10803193 A IL10803193 A IL 10803193A IL 10803193 A IL10803193 A IL 10803193A IL 108031 A0 IL108031 A0 IL 108031A0
Authority
IL
Israel
Prior art keywords
difluoro
pharmaceutical compositions
compositions containing
pentapeptide derivatives
pentapeptide
Prior art date
Application number
IL10803193A
Other languages
English (en)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of IL108031A0 publication Critical patent/IL108031A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL10803193A 1992-12-22 1993-12-15 Difluoro pentapeptide derivatives and pharmaceutical compositions containing them IL108031A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99521792A 1992-12-22 1992-12-22

Publications (1)

Publication Number Publication Date
IL108031A0 true IL108031A0 (en) 1994-04-12

Family

ID=25541529

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10803193A IL108031A0 (en) 1992-12-22 1993-12-15 Difluoro pentapeptide derivatives and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US5760002A (cs)
EP (1) EP0675901A1 (cs)
JP (1) JPH08505143A (cs)
KR (1) KR950704350A (cs)
CN (1) CN1056615C (cs)
AU (1) AU697299B2 (cs)
BR (1) BR9307728A (cs)
CA (1) CA2152267C (cs)
CZ (1) CZ286126B6 (cs)
FI (1) FI953106A7 (cs)
HU (1) HUT72977A (cs)
IL (1) IL108031A0 (cs)
MX (1) MX9400072A (cs)
NO (1) NO952485L (cs)
NZ (1) NZ259274A (cs)
PE (1) PE5195A1 (cs)
PL (1) PL177914B1 (cs)
RU (1) RU2141971C1 (cs)
SG (1) SG54306A1 (cs)
SK (1) SK82795A3 (cs)
TW (1) TW402607B (cs)
WO (1) WO1994014842A1 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002845A (ja) * 2001-04-03 2003-01-08 Univ Nihon 哺乳類の硬組織治療用組成物及びその治療方法
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
PL2398500T3 (pl) 2009-02-20 2019-09-30 2-Bbb Medicines B.V. System dostarczania leków na bazie glutationu
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55500520A (cs) * 1978-07-18 1980-08-14
HU177098B (en) * 1979-01-04 1981-07-28 Gyogyszerkutato Intezet Process for producing new peptidyl-n-carboxy-l-arginin-a
JPS5754157A (en) * 1980-09-19 1982-03-31 Nippon Kayaku Co Ltd L-argininal derivative and its preparation
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
JPS5830300B2 (ja) * 1981-11-02 1983-06-28 三菱化学株式会社 トリペプチドおよびその誘導体の製造法
JPS58164563A (ja) * 1982-03-25 1983-09-29 Dai Ichi Pure Chem Co Ltd 新規ペプチドアルデヒド類及びその製造法
GB2124233B (en) * 1982-07-19 1985-09-18 Nat Res Dev Synthetic peptides and their preparation
CS231228B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes
US4816449A (en) * 1984-08-09 1989-03-28 Immunetech Pharmaceuticals Immunotherapeutic anti-inflammatory peptide agents
US4845242A (en) * 1987-04-28 1989-07-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
AU600226B2 (en) * 1985-02-04 1990-08-09 Merrell Pharmaceuticals Inc. Novel peptidase inhibitors
CH672792A5 (cs) * 1985-02-19 1989-12-29 Sandoz Ag
US5066643A (en) * 1985-02-19 1991-11-19 Sandoz Ltd. Fluorine and chlorine statine or statone containing peptides and method of use
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
EP0204571B1 (en) * 1985-06-07 1992-01-22 Ici Americas Inc. Selected difluoro derivatives
HU200473B (en) * 1985-11-01 1990-06-28 Pfizer Process for producing polypeptides containing difluorocyclostatine and pharmaceutical compositions comprising same
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
GB8613703D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro peptide compounds
NZ223148A (en) * 1987-01-16 1989-10-27 Merrell Dow Pharma Peptide derivatives having peptidase inhibition activity
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
JPH075634B2 (ja) * 1987-10-30 1995-01-25 日東紡績株式会社 トリペプチド類及びこれを含有する抗プラスミン剤
US4902781A (en) * 1987-11-24 1990-02-20 Taisho Pharmaceutical Co., Ltd. Novel tripetide derivatives
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
YU30589A (en) * 1989-02-09 1991-10-31 Imunoloski Z Zagreb New adamantyl containing tripeptides and it's hydrochloride and process for preparing and use
GB8910547D0 (en) * 1989-05-08 1989-06-21 Ici America Inc Substituted ketones
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues

Also Published As

Publication number Publication date
AU697299B2 (en) 1998-10-01
HUT72977A (en) 1996-06-28
PL309638A1 (en) 1995-10-30
CN1056615C (zh) 2000-09-20
RU95113497A (ru) 1997-06-10
CZ164595A3 (en) 1995-12-13
PL177914B1 (pl) 2000-01-31
EP0675901A1 (en) 1995-10-11
RU2141971C1 (ru) 1999-11-27
CN1095072A (zh) 1994-11-16
NZ259274A (en) 1997-10-24
WO1994014842A1 (en) 1994-07-07
FI953106A7 (fi) 1995-07-13
SG54306A1 (en) 1998-11-16
US5760002A (en) 1998-06-02
CA2152267A1 (en) 1994-07-07
SK82795A3 (en) 1995-12-06
PE5195A1 (es) 1995-03-08
CZ286126B6 (cs) 2000-01-12
JPH08505143A (ja) 1996-06-04
NO952485D0 (no) 1995-06-21
KR950704350A (ko) 1995-11-20
NO952485L (no) 1995-08-22
TW402607B (en) 2000-08-21
HU9501844D0 (en) 1995-08-28
CA2152267C (en) 2001-04-17
AU5803994A (en) 1994-07-19
FI953106A0 (fi) 1995-06-21
MX9400072A (es) 1994-08-31
BR9307728A (pt) 1999-08-31

Similar Documents

Publication Publication Date Title
IL111221A0 (en) N-alkyl-n- arylpyrimidinamine derivatives and pharmaceutical compositions containing them
IL103910A0 (en) New peptide derivatives and pharmaceutical compositions containing them
IL105218A0 (en) Hexanones and pharmaceutical compositions containing them
IL105223A0 (en) Cyclohexane-ylidenes and pharmaceutical compositions containing them
IL106431A0 (en) Aminediol derivatives and pharmaceutical compositions containing the same
IL107587A0 (en) Farnesyl derivatives and pharmaceutical compositions containing them
IL105221A0 (en) Cyclohexane derivatives and pharmaceutical compositions containing them
IL105220A0 (en) Cyclohexanylidene compounds and pharmaceutical compositions containing them
GB9224855D0 (en) Pharmaceutical compositions
GB9308014D0 (en) Pharmaceutical compositions
IL110988A0 (en) 4-arylamino-benzopyran derivatives and pharmaceutical compositions containing the same
HUT66864A (en) Pharmaceutical compositions
IL106098A0 (en) Heteroarylnaphthalenes and pharmaceutical compositions containing them
IL105673A0 (en) Purine derivatives and pharmaceutical compositions containing them
IL97122A0 (en) Aromatase-inhibiting androstendiones and pharmaceutical compositions containing them
IL108073A0 (en) Substituted 6-azaandrostenones their preparation and pharmaceutical compositions containing them
ZA948689B (en) New taxicin derivatives their preparation and pharmaceutical compositions containing them
HUT67287A (en) Piperazynil camphor derivatives and pharmaceutical compositions containing them
ZA933426B (en) New dihydroxybenzylamine derivatives their preparation and pharmaceutical compositions which contain them
IL104417A0 (en) Substituted dihydroindene and-acenaphthene derivatives and pharmaceutical compositions containing them
IL108031A0 (en) Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
GB9209874D0 (en) Pharmaceutical compositions
IL108920A0 (en) Acyloxyhexanoic acid derivatives and pharmaceutical compositions containing them
ZA944769B (en) Thf-gamma2 analogs and pharmaceutical compositions comprising them
NZ241331A (en) 3-phenyl-2-alkenamide derivatives and pharmaceutical compositions thereof