IL105673A0 - Purine derivatives and pharmaceutical compositions containing them - Google Patents

Purine derivatives and pharmaceutical compositions containing them

Info

Publication number
IL105673A0
IL105673A0 IL105673A IL10567393A IL105673A0 IL 105673 A0 IL105673 A0 IL 105673A0 IL 105673 A IL105673 A IL 105673A IL 10567393 A IL10567393 A IL 10567393A IL 105673 A0 IL105673 A0 IL 105673A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
compositions containing
purine derivatives
purine
derivatives
Prior art date
Application number
IL105673A
Other versions
IL105673A (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL105673A0 publication Critical patent/IL105673A0/en
Publication of IL105673A publication Critical patent/IL105673A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL105673A 1992-05-14 1993-05-11 Use of n-substituted adenosine derivatives for the preparation of medicaments for treating myocardial or cerebral ischemia, certain novel n-substituted adenosine derivatives and pharmaceutical compositions containing them IL105673A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92626A DK62692D0 (en) 1992-05-14 1992-05-14

Publications (2)

Publication Number Publication Date
IL105673A0 true IL105673A0 (en) 1993-09-22
IL105673A IL105673A (en) 1998-01-04

Family

ID=8095717

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105673A IL105673A (en) 1992-05-14 1993-05-11 Use of n-substituted adenosine derivatives for the preparation of medicaments for treating myocardial or cerebral ischemia, certain novel n-substituted adenosine derivatives and pharmaceutical compositions containing them

Country Status (9)

Country Link
EP (1) EP0603348A1 (en)
JP (1) JPH06508855A (en)
AU (1) AU671995B2 (en)
CA (1) CA2113547A1 (en)
DK (1) DK62692D0 (en)
FI (1) FI940167A (en)
IL (1) IL105673A (en)
NZ (1) NZ252110A (en)
WO (1) WO1993023418A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155292D0 (en) * 1992-12-23 1992-12-23 Novo Nordisk As CHEMICAL COMPOUNDS, THEIR PREPARATION AND USE
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
BR9507683A (en) * 1994-05-10 1997-09-23 Sandoz Ag Adenosine derivatives
EP0704215A3 (en) * 1994-06-02 1998-04-01 Takeda Chemical Industries, Ltd. Inhibitor of vascular permeability enhancer
GB9421133D0 (en) * 1994-10-20 1994-12-07 Glaxo Group Ltd Medicaments
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
CO5180581A1 (en) * 1999-09-30 2002-07-30 Pfizer Prod Inc COMPOUNDS FOR THE TREATMENT OF THE ISCHEMIA PHARMACEUTICAL TIONS THAT CONTAIN THEM FOR THE TREATMENT OF THE ISCHEMIA
US6803457B1 (en) 1999-09-30 2004-10-12 Pfizer, Inc. Compounds for the treatment of ischemia
AU2001260076A1 (en) * 2000-05-15 2001-11-26 Novo-Nordisk A/S Compounds for treating disorders where a decreased level of plasma ffa is desired
US7414036B2 (en) 2002-01-25 2008-08-19 Muscagen Limited Compounds useful as A3 adenosine receptor agonists
EP2021350B1 (en) 2006-03-21 2016-12-21 Rheinische Friedrich-Wilhelms-Universität Bonn Phosphorylated a2a receptor agonists
CZ2009298A3 (en) * 2009-05-14 2010-11-24 Univerzita Palackého v Olomouci Substituted 6-benzylaminopurine ribosides, their use and pharmaceutical composition in which said compounds are comprised
CN102711771B (en) 2010-01-11 2016-05-18 伊诺泰克制药公司 Reduce combination, kit and the method for intraocular pressure
CN102933593A (en) 2010-03-26 2013-02-13 伊诺泰克制药公司 Method of reducing intraocular pressure in humans using n6-cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof
KR20130029049A (en) * 2010-03-26 2013-03-21 이노텍 파마슈티컬스 코포레이션 Adenosine compounds and their use thereof
EA027109B1 (en) 2012-01-26 2017-06-30 Инотек Фармасьютикалс Корпорейшн Anhydrous polymorphs of [(2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate and processes of preparation thereof
MX2015013234A (en) 2013-03-15 2016-04-15 Inotek Pharmaceuticals Corp Ophthalmic formulations.
JP2015172077A (en) * 2015-06-24 2015-10-01 中国医学科学院葯物研究所 Applications of n6-substituted adenosine derivative and n6-substituted adenine derivative to calming, hypnoses, convulsion resistance, epileptic resistance, parkinson disease resistance, and dementia prevention and treatment
GB2582361A (en) * 2019-03-21 2020-09-23 Univ Warwick Adenosine receptor agonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL128629C (en) * 1966-05-07
DE1670077C3 (en) * 1966-05-07 1975-04-24 Boehringer Mannheim Gmbh, 6800 Mannheim Adenosine derivatives and processes for their preparation
NL6717061A (en) * 1966-12-21 1968-06-24
DE2052596A1 (en) * 1970-10-27 1972-05-04 Boehringer Mannheim Gmbh, 6800 Mannheim Novel use of N (6) -substituted adenosine derivatives
DE3406533A1 (en) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim USE OF ADENOSINE DERIVATIVES AS ANTIALLERGICA AND MEDICINAL PRODUCTS CONTAINING THEM
ATE50777T1 (en) * 1984-04-18 1990-03-15 Whitby Research Inc CARDIO VASODILATORS N-6-SUBSTITUTED ADENOSINS.
US4791103A (en) * 1985-02-08 1988-12-13 Warner-Lambert Company 2,N6 -disubstituted adenosines, derivatives and methods of use
JPH0696534B2 (en) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 Anti-dementia agent
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
HUT61567A (en) * 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
DK62592D0 (en) * 1992-05-14 1992-05-14 Novo Nordisk As

Also Published As

Publication number Publication date
EP0603348A1 (en) 1994-06-29
IL105673A (en) 1998-01-04
AU671995B2 (en) 1996-09-19
WO1993023418A1 (en) 1993-11-25
DK62692D0 (en) 1992-05-14
FI940167A (en) 1994-03-03
JPH06508855A (en) 1994-10-06
FI940167A0 (en) 1994-01-13
CA2113547A1 (en) 1993-11-25
AU4061293A (en) 1993-12-13
NZ252110A (en) 1996-07-26

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH Patent void