IL106419A - Method for the preparation of esters N - metamorphic acid of hexahydro - a, 31, 8-trialkylpyrrolo (b) 3 - 2 (indole - 5 - rams from the homologues of physostigmic - Google Patents
Method for the preparation of esters N - metamorphic acid of hexahydro - a, 31, 8-trialkylpyrrolo (b) 3 - 2 (indole - 5 - rams from the homologues of physostigmicInfo
- Publication number
- IL106419A IL106419A IL10641993A IL10641993A IL106419A IL 106419 A IL106419 A IL 106419A IL 10641993 A IL10641993 A IL 10641993A IL 10641993 A IL10641993 A IL 10641993A IL 106419 A IL106419 A IL 106419A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- loweralkyl
- compound
- solvent
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91871992A | 1992-07-21 | 1992-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL106419A0 IL106419A0 (en) | 1993-11-15 |
| IL106419A true IL106419A (en) | 1999-12-31 |
Family
ID=25440831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10641993A IL106419A (en) | 1992-07-21 | 1993-07-20 | Method for the preparation of esters N - metamorphic acid of hexahydro - a, 31, 8-trialkylpyrrolo (b) 3 - 2 (indole - 5 - rams from the homologues of physostigmic |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5498726A (hu) |
| JP (2) | JP2899502B2 (hu) |
| KR (1) | KR940005629A (hu) |
| CN (1) | CN1037443C (hu) |
| AU (1) | AU660550B2 (hu) |
| CA (1) | CA2100908A1 (hu) |
| CZ (1) | CZ284321B6 (hu) |
| FI (2) | FI933264A (hu) |
| HU (1) | HU212600B (hu) |
| IL (1) | IL106419A (hu) |
| MX (1) | MX9304397A (hu) |
| NO (1) | NO301276B1 (hu) |
| NZ (1) | NZ248180A (hu) |
| PH (1) | PH30885A (hu) |
| RU (1) | RU2116307C1 (hu) |
| TW (1) | TW239143B (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866120A (en) * | 1995-11-22 | 1999-02-02 | Advanced Corneal Systems, Inc. | Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase |
| US5665880A (en) * | 1996-10-31 | 1997-09-09 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseretholes |
| US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
| US6495700B1 (en) * | 2002-01-09 | 2002-12-17 | Axonyx, Inc. | Process for producing phenserine and its analog |
| TWI294718B (en) | 2005-12-14 | 2008-03-11 | Ind Tech Res Inst | Frequency modulation-frequency shift keying (fm/fsk) demodulator |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| IT1225462B (it) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
| US4900748A (en) * | 1988-03-04 | 1990-02-13 | The United States Of America As Represented By The Department Of Health And Human Services | Carbamates related to (-)-physostigmine as cholinergic agents |
| US4914102A (en) * | 1989-09-28 | 1990-04-03 | Hoechst Roussel Pharmaceuticals, Inc. | N-aminocarbamates related to physostigmine, pharmacentical compositions and use |
| US5077289A (en) * | 1989-11-30 | 1991-12-31 | Hoechst Roussel Pharmaceuticals Inc. | Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine |
-
1993
- 1993-07-19 FI FI933264A patent/FI933264A/fi unknown
- 1993-07-19 PH PH46537A patent/PH30885A/en unknown
- 1993-07-19 NZ NZ248180A patent/NZ248180A/en unknown
- 1993-07-20 IL IL10641993A patent/IL106419A/en not_active IP Right Cessation
- 1993-07-20 NO NO932616A patent/NO301276B1/no not_active IP Right Cessation
- 1993-07-20 AU AU42049/93A patent/AU660550B2/en not_active Ceased
- 1993-07-20 JP JP5179071A patent/JP2899502B2/ja not_active Expired - Lifetime
- 1993-07-20 RU RU93045705A patent/RU2116307C1/ru active
- 1993-07-20 CA CA002100908A patent/CA2100908A1/en not_active Abandoned
- 1993-07-21 KR KR1019930013763A patent/KR940005629A/ko not_active Application Discontinuation
- 1993-07-21 CZ CZ931473A patent/CZ284321B6/cs not_active IP Right Cessation
- 1993-07-21 HU HU9302110A patent/HU212600B/hu not_active IP Right Cessation
- 1993-07-21 MX MX9304397A patent/MX9304397A/es not_active IP Right Cessation
- 1993-07-21 CN CN93108583A patent/CN1037443C/zh not_active Expired - Fee Related
- 1993-07-21 TW TW082105785A patent/TW239143B/zh active
-
1994
- 1994-03-22 US US08/216,238 patent/US5498726A/en not_active Expired - Fee Related
-
1997
- 1997-01-13 JP JP9003612A patent/JP2949085B2/ja not_active Expired - Lifetime
-
1999
- 1999-04-06 FI FI990752A patent/FI990752A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI990752A0 (fi) | 1999-04-06 |
| NO932616L (no) | 1994-01-24 |
| JPH09176167A (ja) | 1997-07-08 |
| HUT65135A (en) | 1994-04-28 |
| US5498726A (en) | 1996-03-12 |
| NO301276B1 (no) | 1997-10-06 |
| FI990752A (fi) | 1999-04-06 |
| AU4204993A (en) | 1994-01-27 |
| JPH06179678A (ja) | 1994-06-28 |
| PH30885A (en) | 1997-12-23 |
| JP2949085B2 (ja) | 1999-09-13 |
| RU2116307C1 (ru) | 1998-07-27 |
| JP2899502B2 (ja) | 1999-06-02 |
| TW239143B (hu) | 1995-01-21 |
| IL106419A0 (en) | 1993-11-15 |
| NZ248180A (en) | 1995-02-24 |
| KR940005629A (ko) | 1994-03-22 |
| HU9302110D0 (en) | 1993-11-29 |
| NO932616D0 (no) | 1993-07-20 |
| CN1037443C (zh) | 1998-02-18 |
| MX9304397A (es) | 1994-02-28 |
| HU212600B (en) | 1996-09-30 |
| CZ284321B6 (cs) | 1998-10-14 |
| FI933264A0 (fi) | 1993-07-19 |
| AU660550B2 (en) | 1995-06-29 |
| CA2100908A1 (en) | 1994-01-22 |
| CZ147393A3 (en) | 1994-03-16 |
| CN1084174A (zh) | 1994-03-23 |
| FI933264A (fi) | 1994-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU624118B2 (en) | Antibacterial agents | |
| EP0172651B1 (en) | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acids; substituted-5-amino-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds | |
| JP4431389B2 (ja) | 鏡像異性的に純粋なアミノ置換縮合二環式環の合成 | |
| JP3262810B2 (ja) | ケトンの還元用キラル触媒とその製法 | |
| EP0202763B1 (en) | 5,6-difluoronaphthyridines and 5,6,8-trifluoro-quinolines as antibacterial agents | |
| US5700939A (en) | Intermediates useful in camptothecin synthesis | |
| ATE150463T1 (de) | Verfahren zur herstellung von antimikrobiellen quinolonyl-lactamen | |
| JP3174405B2 (ja) | ８−ビニル−および８−エチニル−キノロン−カルボン酸類 | |
| EP2066672A1 (en) | An improved process for the preparation of temozolomide and analogs | |
| IL106419A (en) | Method for the preparation of esters N - metamorphic acid of hexahydro - a, 31, 8-trialkylpyrrolo (b) 3 - 2 (indole - 5 - rams from the homologues of physostigmic | |
| KR940005628A (ko) | 에세레톨로부터의 피소스티그민 카바메이트 유도체의 제조방법 | |
| ZA200100088B (en) | New benzoxazoles with PDE-inhibiting activity. | |
| RU93046065A (ru) | Способ получения производных физостигминкарбамата | |
| CA1338419C (en) | Substituted thienopyrans as antihypertensive agents | |
| KR102068754B1 (ko) | 의약품 합성용 중간체 화합물의 제조 방법 | |
| US3910911A (en) | Production of quinazolinone compounds | |
| Meyers et al. | The synthesis of 1, 1'-spiroalkane or fused annulated 1, 2, 3, 4-tetrahydroisoquinolines using a highly reactive formamidine for metalation-alkylation | |
| KR100519158B1 (ko) | 퀴놀론 카르복실레이트 유도체의 제조방법 | |
| Stecko et al. | Synthesis of polyhydroxylated 7-aminopyrrolizidines and 8-aminoindolizidines | |
| JP3107834B2 (ja) | １−アリール−４−オキソピロロ［３，２−ｃ］キノリン誘導体の製造方法 | |
| CA1235699A (en) | Resolution of racemic derivatives of 5-(1-methyl-5- methylthiopyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2- a) pyrrole-1-carboxylic acid and analogs | |
| USH1737H (en) | 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same | |
| CA2251813A1 (en) | 5,6,7,8-tetrahydropyrido[2,3-d]pyrimidines | |
| NZ239717A (en) | Fluorinated alkyl benzoic acids and esters and their preparation | |
| IL46953A (en) | Triazolo-quinolines and their preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| RH | Patent void |