IL105657A - Process for the preparation of 5-chloroxindole - Google Patents
Process for the preparation of 5-chloroxindoleInfo
- Publication number
- IL105657A IL105657A IL105657A IL10565793A IL105657A IL 105657 A IL105657 A IL 105657A IL 105657 A IL105657 A IL 105657A IL 10565793 A IL10565793 A IL 10565793A IL 105657 A IL105657 A IL 105657A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- alkyl ester
- acid alkyl
- chloroxindole
- chlorophenylethanoic
- Prior art date
Links
- WWJLCYHYLZZXBE-UHFFFAOYSA-N 5-chloro-1,3-dihydroindol-2-one Chemical compound ClC1=CC=C2NC(=O)CC2=C1 WWJLCYHYLZZXBE-UHFFFAOYSA-N 0.000 title abstract 3
- CZGCEKJOLUNIFY-UHFFFAOYSA-N 4-Chloronitrobenzene Chemical compound [O-][N+](=O)C1=CC=C(Cl)C=C1 CZGCEKJOLUNIFY-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- HVZWVEKIQMJYIK-UHFFFAOYSA-N nitryl chloride Chemical compound [O-][N+](Cl)=O HVZWVEKIQMJYIK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH152892 | 1992-05-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL105657A0 IL105657A0 (en) | 1993-09-22 |
| IL105657A true IL105657A (en) | 1997-04-15 |
Family
ID=4212552
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL105657A IL105657A (en) | 1992-05-13 | 1993-05-10 | Process for the preparation of 5-chloroxindole |
| IL11925895A IL119258A (en) | 1992-05-13 | 1995-05-10 | Process for the preparation of alkaline esters of 2-nitro-5-chlorophenyl acetic acid |
| IL11925896A IL119258A0 (en) | 1992-05-13 | 1996-09-17 | A process for the preparation of 2-nitro-5-chlorophenyl ethanoic acid alkyl esters |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11925895A IL119258A (en) | 1992-05-13 | 1995-05-10 | Process for the preparation of alkaline esters of 2-nitro-5-chlorophenyl acetic acid |
| IL11925896A IL119258A0 (en) | 1992-05-13 | 1996-09-17 | A process for the preparation of 2-nitro-5-chlorophenyl ethanoic acid alkyl esters |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5284960A (xx) |
| EP (1) | EP0570817B1 (xx) |
| JP (1) | JPH0632777A (xx) |
| KR (1) | KR930023341A (xx) |
| CN (2) | CN1033581C (xx) |
| AT (1) | ATE152101T1 (xx) |
| AU (1) | AU658060B2 (xx) |
| BR (1) | BR9301786A (xx) |
| CA (1) | CA2096043A1 (xx) |
| CZ (2) | CZ283021B6 (xx) |
| DE (1) | DE59306234D1 (xx) |
| DK (1) | DK0570817T3 (xx) |
| ES (1) | ES2103044T3 (xx) |
| FI (1) | FI932146A (xx) |
| GR (1) | GR3023357T3 (xx) |
| HU (1) | HU213634B (xx) |
| IL (3) | IL105657A (xx) |
| NO (1) | NO179324C (xx) |
| PL (1) | PL173037B1 (xx) |
| SK (1) | SK278473B6 (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5679799A (en) * | 1994-11-04 | 1997-10-21 | K-I Chemical Industry Co., Ltd. | Method for producing oxyindoles |
| US6469181B1 (en) | 1995-01-30 | 2002-10-22 | Catalytica, Inc. | Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060626A (en) * | 1972-01-26 | 1977-11-29 | Boehringer Mannheim G.M.B.H. | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them |
| US4160032A (en) * | 1973-11-21 | 1979-07-03 | Sandoz, Inc. | Oxindoles as sleep-inducers |
| US3882236A (en) * | 1973-12-26 | 1975-05-06 | Lilly Co Eli | Pharmaceutical compositions containing substituted 2-oxo-indolines and the use thereof to treat anxiety and tension |
| US4476315A (en) * | 1982-04-30 | 1984-10-09 | Ethyl Corporation | Nucleophilic substitution process |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| US4659862A (en) * | 1984-05-03 | 1987-04-21 | E. I. Du Pont De Nemours And Company | Process of preparing nitrodihydroaryl carbonyl compounds |
| US4730004A (en) * | 1986-01-22 | 1988-03-08 | Pfizer Inc. | Analgesic and anti-inflammatory 1-acyl-2-oxindole-3-carboxamides |
| US4761485A (en) * | 1987-03-11 | 1988-08-02 | Pfizer Inc. | Synthetic method for indol-2(3H)-ones |
-
1993
- 1993-05-05 AU AU38399/93A patent/AU658060B2/en not_active Ceased
- 1993-05-07 US US08/057,639 patent/US5284960A/en not_active Expired - Fee Related
- 1993-05-07 BR BR9301786A patent/BR9301786A/pt not_active Application Discontinuation
- 1993-05-10 IL IL105657A patent/IL105657A/xx not_active IP Right Cessation
- 1993-05-11 ES ES93107672T patent/ES2103044T3/es not_active Expired - Lifetime
- 1993-05-11 DE DE59306234T patent/DE59306234D1/de not_active Expired - Fee Related
- 1993-05-11 AT AT93107672T patent/ATE152101T1/de not_active IP Right Cessation
- 1993-05-11 JP JP5109342A patent/JPH0632777A/ja active Pending
- 1993-05-11 DK DK93107672.3T patent/DK0570817T3/da not_active Application Discontinuation
- 1993-05-11 EP EP93107672A patent/EP0570817B1/de not_active Expired - Lifetime
- 1993-05-12 KR KR1019930008081A patent/KR930023341A/ko not_active Application Discontinuation
- 1993-05-12 SK SK473-93A patent/SK278473B6/sk unknown
- 1993-05-12 CZ CZ93875A patent/CZ283021B6/cs unknown
- 1993-05-12 FI FI932146A patent/FI932146A/fi not_active Application Discontinuation
- 1993-05-12 CA CA002096043A patent/CA2096043A1/en not_active Abandoned
- 1993-05-12 NO NO931732A patent/NO179324C/no unknown
- 1993-05-12 CZ CZ972192A patent/CZ219297A3/cs unknown
- 1993-05-12 PL PL93298918A patent/PL173037B1/pl unknown
- 1993-05-13 HU HU9301396A patent/HU213634B/hu not_active IP Right Cessation
- 1993-05-13 CN CN93105765A patent/CN1033581C/zh not_active Expired - Fee Related
- 1993-09-09 US US08/118,325 patent/US5395963A/en not_active Expired - Fee Related
-
1995
- 1995-05-10 IL IL11925895A patent/IL119258A/en not_active IP Right Cessation
-
1996
- 1996-01-09 CN CN96101533A patent/CN1144795A/zh active Pending
- 1996-09-17 IL IL11925896A patent/IL119258A0/xx unknown
-
1997
- 1997-05-09 GR GR970401009T patent/GR3023357T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH | Patent void |