IL105607A - Polycyclic macrolides containing atomic tetra, their preparation and pharmaceutical preparations containing them - Google Patents
Polycyclic macrolides containing atomic tetra, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL105607A IL105607A IL105607A IL10560793A IL105607A IL 105607 A IL105607 A IL 105607A IL 105607 A IL105607 A IL 105607A IL 10560793 A IL10560793 A IL 10560793A IL 105607 A IL105607 A IL 105607A
- Authority
- IL
- Israel
- Prior art keywords
- hydroxy
- compound
- group
- formula
- formulae
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929209815A GB9209815D0 (en) | 1992-05-07 | 1992-05-07 | Organic compounds,processes for their production and their use |
GB939304927A GB9304927D0 (en) | 1993-03-10 | 1993-03-10 | Organic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL105607A0 IL105607A0 (en) | 1993-09-22 |
IL105607A true IL105607A (en) | 1998-01-04 |
Family
ID=26300836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL105607A IL105607A (en) | 1992-05-07 | 1993-05-05 | Polycyclic macrolides containing atomic tetra, their preparation and pharmaceutical preparations containing them |
Country Status (25)
Country | Link |
---|---|
US (1) | US5514685A (da) |
EP (1) | EP0569337B1 (da) |
JP (1) | JP2788392B2 (da) |
KR (1) | KR100292311B1 (da) |
CN (1) | CN1037773C (da) |
AT (1) | ATE155787T1 (da) |
AU (1) | AU668152B2 (da) |
CA (1) | CA2095659C (da) |
CY (1) | CY2126B1 (da) |
CZ (1) | CZ291773B6 (da) |
DE (1) | DE69312386T2 (da) |
DK (1) | DK0569337T3 (da) |
ES (1) | ES2105193T3 (da) |
FI (2) | FI102612B1 (da) |
GR (1) | GR3024754T3 (da) |
HU (2) | HUT66531A (da) |
IL (1) | IL105607A (da) |
MY (1) | MY109602A (da) |
NO (1) | NO305865B1 (da) |
NZ (1) | NZ247553A (da) |
PH (1) | PH30456A (da) |
RU (1) | RU2126009C1 (da) |
SG (1) | SG47011A1 (da) |
SK (1) | SK282061B6 (da) |
TW (1) | TW330936B (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY110603A (en) * | 1993-05-27 | 1998-08-29 | Novartis Ag | Tetrahydropyran derivatives |
CN1089233C (zh) | 1994-10-26 | 2002-08-21 | 诺瓦蒂斯有限公司 | 药物组合物 |
IL115742A (en) | 1994-10-26 | 2000-06-01 | Novartis Ag | Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant |
BRPI9909201B8 (pt) | 1998-03-26 | 2021-05-25 | Astellas Pharma Inc | formulação de composto de macrolídeo de liberação controlada |
GB9826656D0 (en) | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
GB0008785D0 (en) | 2000-04-10 | 2000-05-31 | Novartis Ag | Organic compounds |
CA2492989C (en) | 2002-07-23 | 2012-11-20 | Novartis Ag | Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent |
KR100469917B1 (ko) * | 2002-09-09 | 2005-02-02 | (주)조은식품 | 구수한 호박씨가 첨가된 호박엿 및 그 제조방법 |
KR100745493B1 (ko) * | 2005-12-16 | 2007-08-03 | 주식회사농심 | 조직감이 향상된 사출 스낵 및 그 제조 방법 |
EP2552923B1 (en) * | 2010-04-02 | 2014-03-26 | Janssen R&D Ireland | Macrocyclic integrase inhibitors |
CN107106588B (zh) | 2014-10-28 | 2020-08-11 | 山口晃史 | 用于改善妊娠状态的药剂及其使用 |
CN112533599A (zh) | 2018-08-10 | 2021-03-19 | 山口晃史 | 与母体和胎儿的关系中的体液免疫相关的疾病的治疗药 |
AU2019401108A1 (en) | 2018-12-18 | 2021-07-01 | Koushi Yamaguchi | Agent for improving infertility, recurrent miscarriage, and state of pregnancy |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
US5254562A (en) * | 1984-12-03 | 1993-10-19 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
EP0364031B1 (en) * | 1988-10-12 | 1992-12-23 | Merck & Co. Inc. | Hydroxide mediated fk-506 rearrangement process |
CA1316916C (en) * | 1988-10-12 | 1993-04-27 | David Askin | Hydroxide mediated fk-506 rearrangement product |
CA2032159A1 (en) * | 1989-06-14 | 1990-12-15 | Andrew J. F. Edmunds | Heteroatoms-containing tricyclic compounds |
EP0413532A3 (en) * | 1989-08-18 | 1991-05-15 | Fisons Plc | Macrocyclic compounds |
IE904050A1 (en) * | 1989-11-13 | 1991-05-22 | Merck & Co Inc | Aminomacrolides and derivatives having immunosuppressive¹activity |
US5260301A (en) * | 1990-03-01 | 1993-11-09 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical solution containing FK-506 |
GB2246350A (en) * | 1990-07-23 | 1992-01-29 | Fujisawa Pharmaceutical Co | Tricyclo compounds |
EP0480623A1 (en) * | 1990-10-11 | 1992-04-15 | Merck & Co. Inc. | New halomacrolides and derivatives having immunosuppressive activity |
WO1992013862A1 (en) * | 1991-02-05 | 1992-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Lactone compounds |
WO1993004679A1 (en) * | 1991-09-05 | 1993-03-18 | Abbott Laboratories | Macrocyclic immunomodulators |
-
1993
- 1993-04-22 HU HU9301190A patent/HUT66531A/hu unknown
- 1993-05-04 ES ES93810325T patent/ES2105193T3/es not_active Expired - Lifetime
- 1993-05-04 DK DK93810325.6T patent/DK0569337T3/da active
- 1993-05-04 EP EP93810325A patent/EP0569337B1/en not_active Expired - Lifetime
- 1993-05-04 SG SG1996001883A patent/SG47011A1/en unknown
- 1993-05-04 DE DE69312386T patent/DE69312386T2/de not_active Expired - Lifetime
- 1993-05-04 AT AT93810325T patent/ATE155787T1/de not_active IP Right Cessation
- 1993-05-05 MY MYPI93000847A patent/MY109602A/en unknown
- 1993-05-05 PH PH46144A patent/PH30456A/en unknown
- 1993-05-05 NZ NZ247553A patent/NZ247553A/en not_active IP Right Cessation
- 1993-05-05 FI FI932035A patent/FI102612B1/fi not_active IP Right Cessation
- 1993-05-05 SK SK435-93A patent/SK282061B6/sk not_active IP Right Cessation
- 1993-05-05 NO NO931627A patent/NO305865B1/no not_active IP Right Cessation
- 1993-05-05 IL IL105607A patent/IL105607A/en not_active IP Right Cessation
- 1993-05-05 CZ CZ1993829A patent/CZ291773B6/cs not_active IP Right Cessation
- 1993-05-06 CN CN93106551A patent/CN1037773C/zh not_active Expired - Fee Related
- 1993-05-06 CA CA002095659A patent/CA2095659C/en not_active Expired - Fee Related
- 1993-05-06 JP JP5105392A patent/JP2788392B2/ja not_active Expired - Fee Related
- 1993-05-06 KR KR1019930007766A patent/KR100292311B1/ko not_active IP Right Cessation
- 1993-05-06 AU AU38393/93A patent/AU668152B2/en not_active Ceased
- 1993-05-06 RU RU93005029A patent/RU2126009C1/ru not_active IP Right Cessation
- 1993-05-08 TW TW082103599A patent/TW330936B/zh not_active IP Right Cessation
-
1995
- 1995-05-15 US US08/441,492 patent/US5514685A/en not_active Expired - Lifetime
- 1995-06-19 HU HU95P/P00246P patent/HU211135A9/hu unknown
-
1997
- 1997-09-17 GR GR970402399T patent/GR3024754T3/el unknown
-
1998
- 1998-11-16 FI FI982476A patent/FI982476A0/fi unknown
-
1999
- 1999-02-03 CY CY9900004A patent/CY2126B1/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR0166074B1 (ko) | 헤테로원자-함유 트리사이클릭 화합물 | |
EP0109047B1 (en) | Total synthesis of antitumor antibiotics | |
US5514685A (en) | Heteroatom-containing tricyclic compounds | |
AU641410B2 (en) | Antiinflammatory and immunosuppressant triheterocyclic FK506-like compounds and processes for their preparation | |
JPH05194530A (ja) | 免疫抑制活性を有するフルオロマクロライド | |
US5493019A (en) | Tetrahydropyran derivatives | |
US5352671A (en) | Heteroatoms-containing tricyclic compounds | |
AU648806B2 (en) | Cyclopentylvinyl substituted macrolides | |
US5200411A (en) | Heteroatoms-containing tricyclic compounds | |
FR2639637A1 (fr) | Derives cycliques et leurs metabolites, leur preparation et leur utilisation comme medicaments | |
PL173506B1 (pl) | Związki tricykliczne zawierające heteroatomy | |
IL96268A (en) | Tricyclic macrolides containing the trout atoms, converted by cycloalkyl, their preparation and pharmaceutical preparations containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |