DK0569337T3 - Heteroatomholdige tricykliske forbindelser - Google Patents

Heteroatomholdige tricykliske forbindelser

Info

Publication number
DK0569337T3
DK0569337T3 DK93810325.6T DK93810325T DK0569337T3 DK 0569337 T3 DK0569337 T3 DK 0569337T3 DK 93810325 T DK93810325 T DK 93810325T DK 0569337 T3 DK0569337 T3 DK 0569337T3
Authority
DK
Denmark
Prior art keywords
heteroatomic
tricyclic compounds
compounds
various
immunosuppressant
Prior art date
Application number
DK93810325.6T
Other languages
English (en)
Inventor
Karl Baumann
Original Assignee
Sandoz Ag
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929209815A external-priority patent/GB9209815D0/en
Priority claimed from GB939304927A external-priority patent/GB9304927D0/en
Application filed by Sandoz Ag, Ciba Geigy Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of DK0569337T3 publication Critical patent/DK0569337T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
DK93810325.6T 1992-05-07 1993-05-04 Heteroatomholdige tricykliske forbindelser DK0569337T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209815A GB9209815D0 (en) 1992-05-07 1992-05-07 Organic compounds,processes for their production and their use
GB939304927A GB9304927D0 (en) 1993-03-10 1993-03-10 Organic compounds

Publications (1)

Publication Number Publication Date
DK0569337T3 true DK0569337T3 (da) 1998-01-19

Family

ID=26300836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93810325.6T DK0569337T3 (da) 1992-05-07 1993-05-04 Heteroatomholdige tricykliske forbindelser

Country Status (25)

Country Link
US (1) US5514685A (da)
EP (1) EP0569337B1 (da)
JP (1) JP2788392B2 (da)
KR (1) KR100292311B1 (da)
CN (1) CN1037773C (da)
AT (1) ATE155787T1 (da)
AU (1) AU668152B2 (da)
CA (1) CA2095659C (da)
CY (1) CY2126B1 (da)
CZ (1) CZ291773B6 (da)
DE (1) DE69312386T2 (da)
DK (1) DK0569337T3 (da)
ES (1) ES2105193T3 (da)
FI (2) FI102612B1 (da)
GR (1) GR3024754T3 (da)
HU (2) HUT66531A (da)
IL (1) IL105607A (da)
MY (1) MY109602A (da)
NO (1) NO305865B1 (da)
NZ (1) NZ247553A (da)
PH (1) PH30456A (da)
RU (1) RU2126009C1 (da)
SG (1) SG47011A1 (da)
SK (1) SK282061B6 (da)
TW (1) TW330936B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
IL129547A (en) 1994-10-26 2001-01-11 Novartis Ag Pharmaceutical compositions comprising a macrolide and an acid
EP0786986B1 (en) 1994-10-26 2002-03-20 Novartis AG Use of an unsaturated fatty alcohol
ATE464900T1 (de) 1998-03-26 2010-05-15 Astellas Pharma Inc Retardpräparat mit makroliden wie tacrolimus
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
WO2004009056A1 (en) 2002-07-23 2004-01-29 Novartis Ag Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
KR100469917B1 (ko) * 2002-09-09 2005-02-02 (주)조은식품 구수한 호박씨가 첨가된 호박엿 및 그 제조방법
KR100745493B1 (ko) * 2005-12-16 2007-08-03 주식회사농심 조직감이 향상된 사출 스낵 및 그 제조 방법
WO2011121105A1 (en) * 2010-04-02 2011-10-06 Tibotec Pharmaceuticals Macrocyclic integrase inhibitors
EP3246036B1 (en) 2014-10-28 2021-10-13 Koushi Yamaguchi Medicine for improving pregnancy-induced hypertension syndrome
AU2019318035A1 (en) 2018-08-10 2021-03-04 Koushi Yamaguchi Therapeutic agent for humoral immunity-related diseases in materno-fetal relationship
EP3900729A4 (en) 2018-12-18 2022-09-07 Koushi Yamaguchi AGENT FOR TREATING INFERTILITY, RECURRENT MISSORAGE AND IMPROVING PREGNANCY

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5254562A (en) * 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
EP0364031B1 (en) * 1988-10-12 1992-12-23 Merck & Co. Inc. Hydroxide mediated fk-506 rearrangement process
CA1316916C (en) * 1988-10-12 1993-04-27 David Askin Hydroxide mediated fk-506 rearrangement product
EP0402931A1 (en) * 1989-06-14 1990-12-19 Sandoz Ltd. Heteroatoms-containing tricyclic compounds
EP0413532A3 (en) * 1989-08-18 1991-05-15 Fisons Plc Macrocyclic compounds
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
GB2246350A (en) * 1990-07-23 1992-01-29 Fujisawa Pharmaceutical Co Tricyclo compounds
EP0480623A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. New halomacrolides and derivatives having immunosuppressive activity
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
CA2103453A1 (en) * 1991-09-05 1993-03-06 Jay R. Luly Macrocyclic immunomodulators

Also Published As

Publication number Publication date
FI102612B (fi) 1999-01-15
SK282061B6 (sk) 2001-10-08
CA2095659C (en) 2005-08-09
AU3839393A (en) 1993-11-11
CY2126B1 (en) 2002-06-21
HU211135A9 (en) 1995-10-30
CN1037773C (zh) 1998-03-18
DE69312386D1 (de) 1997-08-28
CA2095659A1 (en) 1993-11-08
HUT66531A (en) 1994-12-28
FI102612B1 (fi) 1999-01-15
CZ291773B6 (cs) 2003-05-14
SG47011A1 (en) 1998-03-20
ATE155787T1 (de) 1997-08-15
KR100292311B1 (ko) 2001-09-17
TW330936B (en) 1998-05-01
ES2105193T3 (es) 1997-10-16
DE69312386T2 (de) 1998-01-29
FI982476A0 (fi) 1998-11-16
MY109602A (en) 1997-03-31
NO305865B1 (no) 1999-08-09
IL105607A (en) 1998-01-04
SK43593A3 (en) 1995-07-11
KR940005631A (ko) 1994-03-22
CN1083486A (zh) 1994-03-09
IL105607A0 (en) 1993-09-22
NO931627D0 (no) 1993-05-05
AU668152B2 (en) 1996-04-26
FI932035A (fi) 1993-11-08
RU2126009C1 (ru) 1999-02-10
CZ82993A3 (en) 1994-01-19
EP0569337B1 (en) 1997-07-23
JPH0641144A (ja) 1994-02-15
FI932035A0 (fi) 1993-05-05
NO931627L (no) 1993-11-08
EP0569337A1 (en) 1993-11-10
PH30456A (en) 1997-05-28
US5514685A (en) 1996-05-07
HU9301190D0 (en) 1993-07-28
NZ247553A (en) 1995-07-26
GR3024754T3 (en) 1997-12-31
JP2788392B2 (ja) 1998-08-20

Similar Documents

Publication Publication Date Title
DE69319976T2 (de) 7-Substituierte-9-substituierte Glycylamido-6-Demethyl-6-Deoxytetracycline
DE69331774T2 (de) 7-Substituierte-8-substituierte-9-substituierte Amino-7-Demethyl-6-Deoxy-Tetracycline als antibiotische Mittel
DK0569337T3 (da) Heteroatomholdige tricykliske forbindelser
ES2161220T3 (es) 9-((glicil sustituido)amido)-6-desmetil-6-desoxitetraciclinas como agentes antibioticos.
MX9304646A (es) Nuevas 7-(sustituido)-8-(sustituido)d-9-[(glicilo sustituido)amido]-6-desmetil-6-desoxitetraciclinasy metodo para su produccion.
FI950697A0 (fi) IL-4:n ja/tai IL-10:n uudet käytöt ja vasta-aineet niitä vastaan
PT618190E (pt) 9-¬glicil substituido)amido|-6-(substituido)-5-hidroxi-6-desoxitetraciclinas
NO308302B1 (no) Tetrahydropyranderivativer, farmasøytisk preparat inneholdende slike derivater samt anvendelse derav
GB2294927B (en) New 2,2,6,6-tetramethyl-piperidine derivatives for use as stabilizing agents for organic materials against light,heat and oxidation
FI953106A (fi) Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina
DE69313931D1 (de) Polycyclische 31668P- und 31668U-Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als antibiotische oder antitumorale Arzneistoffe
ES2086395T3 (es) Fosfolipidos para el tratamiento de esclerosis multiple.
GB9522273D0 (en) New 2,2,6,6-tetramethyl-piperidine derivatives for use as stabilizing agents for organic materials against light,heat and oxidation