IL105449A - The use of bisphenylalkylpiperazines for the manufacture of medicines for the treatment of symptoms resulting from the misuse of certain substances and pharmaceutical preparations containing bisphenylalk - Google Patents

The use of bisphenylalkylpiperazines for the manufacture of medicines for the treatment of symptoms resulting from the misuse of certain substances and pharmaceutical preparations containing bisphenylalk

Info

Publication number
IL105449A
IL105449A IL105449A IL10544993A IL105449A IL 105449 A IL105449 A IL 105449A IL 105449 A IL105449 A IL 105449A IL 10544993 A IL10544993 A IL 10544993A IL 105449 A IL105449 A IL 105449A
Authority
IL
Israel
Prior art keywords
hydrogen
carbon atoms
alkyl
halogen
different
Prior art date
Application number
IL105449A
Other languages
English (en)
Hebrew (he)
Other versions
IL105449A0 (en
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Publication of IL105449A0 publication Critical patent/IL105449A0/xx
Publication of IL105449A publication Critical patent/IL105449A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL105449A 1992-04-21 1993-04-19 The use of bisphenylalkylpiperazines for the manufacture of medicines for the treatment of symptoms resulting from the misuse of certain substances and pharmaceutical preparations containing bisphenylalk IL105449A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9201239A SE9201239D0 (sv) 1992-04-21 1992-04-21 Agents for treating substance abuse disorders

Publications (2)

Publication Number Publication Date
IL105449A0 IL105449A0 (en) 1993-08-18
IL105449A true IL105449A (en) 1998-02-22

Family

ID=20386004

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105449A IL105449A (en) 1992-04-21 1993-04-19 The use of bisphenylalkylpiperazines for the manufacture of medicines for the treatment of symptoms resulting from the misuse of certain substances and pharmaceutical preparations containing bisphenylalk

Country Status (26)

Country Link
US (1) US5565455A (xx)
EP (1) EP0637242B1 (xx)
JP (1) JP3245642B2 (xx)
KR (1) KR100321319B1 (xx)
AT (1) ATE184484T1 (xx)
AU (1) AU659941B2 (xx)
BG (1) BG62154B1 (xx)
BR (1) BR9306361A (xx)
CA (1) CA2118512C (xx)
CZ (1) CZ281296B6 (xx)
DE (1) DE69326459T2 (xx)
DK (1) DK0637242T3 (xx)
EE (1) EE02974B1 (xx)
ES (1) ES2139007T3 (xx)
GR (1) GR3032030T3 (xx)
HU (1) HU223463B1 (xx)
IL (1) IL105449A (xx)
NO (2) NO308827B1 (xx)
PH (1) PH31051A (xx)
RO (1) RO117150B1 (xx)
RU (1) RU2126254C1 (xx)
SE (1) SE9201239D0 (xx)
SK (1) SK279940B6 (xx)
UA (1) UA27884C2 (xx)
WO (1) WO1993020821A1 (xx)
ZA (1) ZA932757B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5316759A (en) * 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
SE9201956D0 (sv) * 1992-06-25 1992-06-25 Kabi Pharmacia Ab Novel nicotinicacid esters
SE9601708D0 (sv) 1996-05-06 1996-05-06 Pharmacia Ab Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders
PL203140B1 (pl) 1997-10-27 2009-08-31 Neurosearch As Pochodna homopiperazyny, kompozycja farmaceutyczna zawierająca te pochodne i zastosowanie tej pochodnej
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
US6344222B1 (en) 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US6090780A (en) * 1999-04-07 2000-07-18 Chandon Prasad Histidyl-proline diketopiperazine and method of use
DK1551372T3 (en) 2002-09-20 2018-07-23 Alpharma Pharmaceuticals Llc SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES
WO2007149438A2 (en) 2006-06-19 2007-12-27 Alpharma, Inc. Pharmaceutical compositions
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2958694A (en) * 1959-06-22 1960-11-01 Janssen Paul Adriaan Jan 1-(aroylalkyl)-4-(2'-pyridyl) piperazines
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US2979508A (en) * 1959-10-12 1961-04-11 Paul A J Janssen Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4766215A (en) * 1987-02-27 1988-08-23 American Home Products Corporation Histamine H1 -receptor antagonists
SE8701375D0 (sv) * 1987-04-02 1987-04-02 Leo Ab Novel pyridyl- and pyrimidyl derivatives
US5217987A (en) * 1989-10-30 1993-06-08 Berger Stephen P Dopamine uptake inhibitors in reducing substance abuse and/or craving
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use

Also Published As

Publication number Publication date
IL105449A0 (en) 1993-08-18
PH31051A (en) 1998-02-03
RU2126254C1 (ru) 1999-02-20
BG99129A (bg) 1995-08-28
EP0637242A1 (en) 1995-02-08
NO943977L (no) 1994-10-20
NO308827B1 (no) 2000-11-06
AU4043793A (en) 1993-11-18
SK279940B6 (sk) 1999-06-11
EE02974B1 (et) 1997-04-15
BG62154B1 (bg) 1999-04-30
KR950701221A (ko) 1995-03-23
SE9201239D0 (sv) 1992-04-21
CZ260694A3 (en) 1995-09-13
RO117150B1 (ro) 2001-11-30
SK126994A3 (en) 1995-07-11
AU659941B2 (en) 1995-06-01
KR100321319B1 (ko) 2002-07-27
RU94045866A (ru) 1996-10-20
NO318461B1 (no) 2005-03-21
US5565455A (en) 1996-10-15
DK0637242T3 (da) 2000-03-27
NO20004169L (no) 1994-10-20
HU223463B1 (hu) 2004-07-28
ES2139007T3 (es) 2000-02-01
ZA932757B (en) 1993-10-28
HUT71420A (en) 1995-11-28
NO943977D0 (no) 1994-10-20
JP3245642B2 (ja) 2002-01-15
BR9306361A (pt) 1998-06-30
NO20004169D0 (no) 2000-08-21
UA27884C2 (uk) 2000-10-16
DE69326459D1 (de) 1999-10-21
CZ281296B6 (cs) 1996-08-14
CA2118512A1 (en) 1993-10-28
HU9403020D0 (en) 1994-12-28
DE69326459T2 (de) 2000-03-23
ATE184484T1 (de) 1999-10-15
CA2118512C (en) 2004-07-27
WO1993020821A1 (en) 1993-10-28
JPH08503449A (ja) 1996-04-16
GR3032030T3 (en) 2000-03-31
EP0637242B1 (en) 1999-09-15

Similar Documents

Publication Publication Date Title
AU653797B2 (en) New use of diphenylbutyl-piperazinecarboxamides in the treatment of substance disorders
EP0637242B1 (en) Agents for treating substance abuse disorders
US6221858B1 (en) Pyridyl-and pyrimidyl-piperazines in the treatment of substance abuse disorders
KR100491027B1 (ko) 물질남용질환치료를위한피리딜-및피리미딜-피페라진
MXPA98009265A (en) Piridil- and pyrimidil-piperazines in the treatment of disorders from the abuse of sustain
MacGregor Non nuclear amino derivatives of fluorene
Lowry et al. Controlled and noncontrolled but commonly abused substances
IE911996A1 (en) Agents for treating addiction to habit-forming drugs

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
HP Change in proprietorship
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees