IL104238A - Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL104238A
IL104238A IL10423892A IL10423892A IL104238A IL 104238 A IL104238 A IL 104238A IL 10423892 A IL10423892 A IL 10423892A IL 10423892 A IL10423892 A IL 10423892A IL 104238 A IL104238 A IL 104238A
Authority
IL
Israel
Prior art keywords
compound
group
formula
carbon atoms
thiazolidine
Prior art date
Application number
IL10423892A
Other languages
English (en)
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IL104238A publication Critical patent/IL104238A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL10423892A 1991-12-26 1992-12-25 Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same IL104238A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (1)

Publication Number Publication Date
IL104238A true IL104238A (en) 1996-10-31

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10423892A IL104238A (en) 1991-12-26 1992-12-25 Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (21)

Country Link
EP (1) EP0549365B1 (de)
JP (1) JP2833949B2 (de)
CN (1) CN1032751C (de)
AT (1) ATE126221T1 (de)
AU (1) AU654223B2 (de)
CA (1) CA2086277A1 (de)
CZ (1) CZ389792A3 (de)
DE (1) DE69204041T2 (de)
DK (1) DK0549365T3 (de)
ES (1) ES2078671T3 (de)
FI (1) FI925849A7 (de)
GR (1) GR3017632T3 (de)
HK (1) HK196095A (de)
HU (1) HU215450B (de)
IL (1) IL104238A (de)
MX (1) MX9207595A (de)
NO (1) NO302471B1 (de)
NZ (1) NZ245612A (de)
RU (1) RU2095354C1 (de)
TW (1) TW211007B (de)
ZA (1) ZA9210021B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
RU2151145C1 (ru) * 1994-04-11 2000-06-20 Санкио Компани Лимитед Промежуточное соединение для получения гетероциклических соединений, обладающих антидиабетической активностью
EP0783888A1 (de) * 1995-12-26 1997-07-16 Sankyo Company Limited Verwendung von Troglitazone und verwandten Thiazolidinedionen zur Herstellung eines Medikaments für die Behandlung und Vorbeugung der Osteoporose
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
DE19828114A1 (de) * 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) * 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19926233C1 (de) * 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
ES2248242T3 (es) * 2000-04-21 2006-03-16 Pfizer Products Inc. Ligandos de receptores tiroideos.
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
WO2001081328A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics Thiazolidinedione analogues and their use for the treatment of diabetes
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
PL2001469T3 (pl) 2006-03-16 2012-10-31 Metabolic Solutions Dev Co Llc Analogi tiazolidynodionu
MX356584B (es) 2006-03-16 2018-06-05 Metabolic Solutions Dev Co Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica.
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
NZ597381A (en) * 2007-09-14 2013-03-28 Metabolic Solutions Dev Co Llc Thiazolidinedione analogues for the treatment of diabetes and inflammatory diseases
DK2513070T3 (en) 2009-12-15 2018-01-22 Cirius Therapeutics Inc PPAR-sparing thiazolidinedione salts for the treatment of metabolic disorders
WO2011133442A1 (en) * 2010-04-19 2011-10-27 Metabolic Solutions Development Company Novel synthesis for thiazolidinedione compounds
AU2011242844A1 (en) * 2010-04-21 2012-11-01 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues
WO2012021476A1 (en) 2010-08-10 2012-02-16 Metabolic Solutions Development Company, Llc Novel synthesis for thiazolidinedione compounds
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
HU9204130D0 (en) 1993-04-28
CN1074680A (zh) 1993-07-28
GR3017632T3 (en) 1996-01-31
JP2833949B2 (ja) 1998-12-09
AU3043192A (en) 1993-07-01
RU2095354C1 (ru) 1997-11-10
CA2086277A1 (en) 1993-06-27
NO302471B1 (no) 1998-03-09
TW211007B (de) 1993-08-11
HK196095A (en) 1996-01-05
CZ389792A3 (en) 1994-01-19
HUT67788A (en) 1995-04-28
DK0549365T3 (da) 1995-12-18
AU654223B2 (en) 1994-10-27
DE69204041T2 (de) 1996-03-28
MX9207595A (es) 1994-06-30
FI925849A7 (fi) 1993-06-27
CN1032751C (zh) 1996-09-11
NZ245612A (en) 1994-06-27
NO924964L (no) 1993-06-28
EP0549365A1 (de) 1993-06-30
NO924964D0 (no) 1992-12-22
ES2078671T3 (es) 1995-12-16
EP0549365B1 (de) 1995-08-09
ZA9210021B (en) 1993-07-02
JPH05239041A (ja) 1993-09-17
HU215450B (hu) 1999-04-28
FI925849A0 (fi) 1992-12-23
DE69204041D1 (de) 1995-09-14
ATE126221T1 (de) 1995-08-15

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force