IL103692A0 - Antithrombotic agents - Google Patents
Antithrombotic agentsInfo
- Publication number
- IL103692A0 IL103692A0 IL103692A IL10369292A IL103692A0 IL 103692 A0 IL103692 A0 IL 103692A0 IL 103692 A IL103692 A IL 103692A IL 10369292 A IL10369292 A IL 10369292A IL 103692 A0 IL103692 A0 IL 103692A0
- Authority
- IL
- Israel
- Prior art keywords
- antithrombotic agents
- antithrombotic
- agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79088591A | 1991-11-12 | 1991-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL103692A0 true IL103692A0 (en) | 1993-04-04 |
Family
ID=25152024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL103692A IL103692A0 (en) | 1991-11-12 | 1992-11-09 | Antithrombotic agents |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0542525B1 (fi) |
| JP (1) | JP3159806B2 (fi) |
| KR (1) | KR930009993A (fi) |
| CN (1) | CN1074438A (fi) |
| AU (2) | AU646767B2 (fi) |
| BR (1) | BR9204361A (fi) |
| CA (1) | CA2082748A1 (fi) |
| CZ (1) | CZ333492A3 (fi) |
| DE (1) | DE69226152T2 (fi) |
| ES (1) | ES2120993T3 (fi) |
| FI (1) | FI925124A (fi) |
| HU (1) | HUT65858A (fi) |
| IL (1) | IL103692A0 (fi) |
| MX (1) | MX9206474A (fi) |
| NO (1) | NO924326L (fi) |
| NZ (1) | NZ245039A (fi) |
| TW (1) | TW232686B (fi) |
| YU (1) | YU97292A (fi) |
| ZA (1) | ZA928581B (fi) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9103612D0 (sv) * | 1991-12-04 | 1991-12-04 | Astra Ab | New peptide derivatives |
| US5783563A (en) * | 1993-06-03 | 1998-07-21 | Astra Aktiebolag | Method for treatment or prophylaxis of venous thrombosis |
| US6984627B1 (en) | 1993-06-03 | 2006-01-10 | Astrazeneca Ab | Peptide derivatives |
| SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
| US5488037A (en) * | 1994-03-04 | 1996-01-30 | Eli Lilly And Company | Antithrombotic agents |
| ZA951618B (en) * | 1994-03-04 | 1996-08-27 | Lilly Co Eli | Antithrombotic agents |
| US5436229A (en) * | 1994-03-04 | 1995-07-25 | Eli Lilly And Company | Bisulfite adducts of arginine aldehydes |
| US5602101A (en) * | 1994-03-04 | 1997-02-11 | Eli Lilly And Company | Antithrombotic agents |
| ZA951617B (en) * | 1994-03-04 | 1997-02-27 | Lilly Co Eli | Antithrombotic agents. |
| US5484772A (en) * | 1994-03-04 | 1996-01-16 | Eli Lilly And Company | Antithrombotic agents |
| US5726159A (en) * | 1994-03-04 | 1998-03-10 | Eli Lilly And Company | Antithrombotic agents |
| US5705487A (en) * | 1994-03-04 | 1998-01-06 | Eli Lilly And Company | Antithrombotic agents |
| US5707966A (en) * | 1994-03-04 | 1998-01-13 | Eli Lilly And Company | Antithrombotic agents |
| US5885967A (en) * | 1994-03-04 | 1999-03-23 | Eli Lilly And Company | Antithrombotic agents |
| CA2143533A1 (en) * | 1994-03-04 | 1995-09-05 | Kenneth D. Kurz | Antithrombotic agents |
| US5439888A (en) * | 1994-03-04 | 1995-08-08 | Eli Lilly And Company | Antithrombotic agents |
| JPH09509943A (ja) * | 1994-03-04 | 1997-10-07 | イーライ・リリー・アンド・カンパニー | 抗血栓剤 |
| DE4421052A1 (de) | 1994-06-17 | 1995-12-21 | Basf Ag | Neue Thrombininhibitoren, ihre Herstellung und Verwendung |
| SE9404196D0 (sv) * | 1994-12-02 | 1994-12-02 | Astra Ab | New antithrombotic formulation |
| SK104697A3 (en) * | 1995-02-17 | 1998-11-04 | Basf Ag | Novel dipeptide amidines as thrombin inhibitors |
| US5710130A (en) * | 1995-02-27 | 1998-01-20 | Eli Lilly And Company | Antithrombotic agents |
| US5914319A (en) * | 1995-02-27 | 1999-06-22 | Eli Lilly And Company | Antithrombotic agents |
| SA96170106A (ar) * | 1995-07-06 | 2005-12-03 | أسترا أكتيبولاج | مشتقات حامض أميني جديدة |
| AR005245A1 (es) | 1995-12-21 | 1999-04-28 | Astrazeneca Ab | Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion |
| SE9602263D0 (sv) | 1996-06-07 | 1996-06-07 | Astra Ab | New amino acid derivatives |
| SE9602646D0 (sv) | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically-useful compounds |
| AU7292398A (en) | 1997-05-15 | 1998-12-08 | Eli Lilly And Company | Antithrombotic compound |
| AR013084A1 (es) | 1997-06-19 | 2000-12-13 | Astrazeneca Ab | Derivados de amidino utiles como inhibidores de la trombina, composicion farmaceutica, utilizacion de dichos compuestos para la preparacion demedicamentos y proceso para la preparacion de los compuestos mencionados |
| SE9704543D0 (sv) | 1997-12-05 | 1997-12-05 | Astra Ab | New compounds |
| HUP0100082A3 (en) | 1998-01-26 | 2001-12-28 | Abbott Gmbh & Co Kg | Thrombin inhibitor, peptide derivatives, pharmaceutical compositions comprising thereof and their use |
| SE9804313D0 (sv) | 1998-12-14 | 1998-12-14 | Astra Ab | New compounds |
| TR200102037T2 (tr) | 1999-01-13 | 2001-10-22 | Astrazeneca Ab | Yeni amidinobenzilamin türevleri ve trombin engelleyiciler olarak kullanılmaları. |
| AR023510A1 (es) | 1999-04-21 | 2002-09-04 | Astrazeneca Ab | Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina. |
| WO2001079208A1 (fr) * | 2000-04-19 | 2001-10-25 | Kaneka Corporation | Nouveau derive d'azetidine et procede de preparation de celui-ci |
| SE0001803D0 (sv) | 2000-05-16 | 2000-05-16 | Astrazeneca Ab | New compounds i |
| US6433186B1 (en) | 2000-08-16 | 2002-08-13 | Astrazeneca Ab | Amidino derivatives and their use as thormbin inhibitors |
| US7129233B2 (en) | 2000-12-01 | 2006-10-31 | Astrazeneca Ab | Mandelic acid derivatives and their use as thrombin inhibitors |
| AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| AR034517A1 (es) | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| SE0201661D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| SE0201659D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| US7781424B2 (en) | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| US7795205B2 (en) | 2004-04-12 | 2010-09-14 | Canyon Pharmaceuticals, Inc. | Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor |
| RU2008139428A (ru) * | 2006-03-06 | 2010-05-20 | Хьюмэджин, Инк. (Us) | Способ получения рекомбинантного тромбина и фибриногена человека |
| CN101190895B (zh) * | 2006-11-30 | 2010-05-26 | 首都医科大学 | N-[(3s)-1,2,3,4-四氢异喹啉-3-甲酰基]氨基酸、其制备方法及应用 |
| TW200827336A (en) | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
| CN101318933B (zh) * | 2007-06-04 | 2010-08-11 | 北京大学 | 具有抗血栓活性的异喹啉化合物、其制备方法及应用 |
| CN102127097A (zh) * | 2010-01-15 | 2011-07-20 | 首都医科大学 | N-（3s-1,2,3,4-四氢异喹啉-3-甲酰基）氨基酸铜络合物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318904A (en) * | 1980-04-25 | 1982-03-09 | Research Corporation | Peptide affinity labels for thrombin and other trypsin-like proteases |
| HU192646B (en) * | 1984-12-21 | 1987-06-29 | Gyogyszerkutato Intezet | Process for preparing new n-alkyl-peptide aldehydes |
| SE9102462D0 (sv) * | 1991-08-28 | 1991-08-28 | Astra Ab | New isosteric peptides |
-
1992
- 1992-11-06 ZA ZA928581A patent/ZA928581B/xx unknown
- 1992-11-06 NZ NZ245039A patent/NZ245039A/en unknown
- 1992-11-06 CZ CS923334A patent/CZ333492A3/cs unknown
- 1992-11-09 IL IL103692A patent/IL103692A0/xx unknown
- 1992-11-10 NO NO92924326A patent/NO924326L/no unknown
- 1992-11-10 KR KR1019920021008A patent/KR930009993A/ko not_active Application Discontinuation
- 1992-11-10 BR BR929204361A patent/BR9204361A/pt not_active Application Discontinuation
- 1992-11-11 HU HU9203545A patent/HUT65858A/hu unknown
- 1992-11-11 AU AU28298/92A patent/AU646767B2/en not_active Ceased
- 1992-11-11 DE DE69226152T patent/DE69226152T2/de not_active Expired - Fee Related
- 1992-11-11 EP EP92310292A patent/EP0542525B1/en not_active Expired - Lifetime
- 1992-11-11 FI FI925124A patent/FI925124A/fi not_active Application Discontinuation
- 1992-11-11 CN CN92114384A patent/CN1074438A/zh active Pending
- 1992-11-11 MX MX9206474A patent/MX9206474A/es unknown
- 1992-11-11 AU AU28312/92A patent/AU2831292A/en not_active Abandoned
- 1992-11-11 ES ES92310292T patent/ES2120993T3/es not_active Expired - Lifetime
- 1992-11-11 YU YU97292A patent/YU97292A/sh unknown
- 1992-11-12 JP JP30236092A patent/JP3159806B2/ja not_active Expired - Fee Related
- 1992-11-12 CA CA002082748A patent/CA2082748A1/en not_active Abandoned
- 1992-11-23 TW TW081109359A patent/TW232686B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69226152D1 (de) | 1998-08-13 |
| AU2831292A (en) | 1993-05-13 |
| EP0542525A3 (en) | 1994-06-29 |
| JP3159806B2 (ja) | 2001-04-23 |
| CN1074438A (zh) | 1993-07-21 |
| ZA928581B (en) | 1994-05-06 |
| AU2829892A (en) | 1993-05-13 |
| HU9203545D0 (en) | 1993-01-28 |
| NO924326L (no) | 1993-05-14 |
| HUT65858A (en) | 1994-07-28 |
| TW232686B (fi) | 1994-10-21 |
| KR930009993A (ko) | 1993-06-21 |
| ES2120993T3 (es) | 1998-11-16 |
| BR9204361A (pt) | 1993-06-01 |
| DE69226152T2 (de) | 1998-12-10 |
| EP0542525B1 (en) | 1998-07-08 |
| CZ333492A3 (en) | 1993-09-15 |
| NZ245039A (en) | 1994-12-22 |
| YU97292A (sh) | 1995-10-24 |
| CA2082748A1 (en) | 1993-05-13 |
| MX9206474A (es) | 1993-10-01 |
| NO924326D0 (no) | 1992-11-10 |
| EP0542525A2 (en) | 1993-05-19 |
| FI925124A0 (fi) | 1992-11-11 |
| AU646767B2 (en) | 1994-03-03 |
| FI925124A (fi) | 1993-05-13 |
| JPH05221964A (ja) | 1993-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL103692A0 (en) | Antithrombotic agents | |
| DE4190756D2 (en) | Mikrotom | |
| DE69125252D1 (en) | Röntgentherapie-simulatormachine | |
| EP0440282A3 (en) | Sensormatrix | |
| DE69126781D1 (en) | Fabry-perot-modulator | |
| DE69116171D1 (en) | Photo- und biologisch-abbaubare polyethen-copolymere | |
| DE69127252D1 (en) | Linearlager | |
| DE4092449D2 (de) | Taschenfederkernmatratze | |
| AU111085S (en) | Sunlounger | |
| EP0442596A3 (en) | Echelle-polychromator | |
| DE4191708D2 (en) | Festkoerperlaser | |
| GB9024290D0 (en) | Fitting | |
| GB9004086D0 (en) | Container-cap combination | |
| CS262591A3 (en) | Indolonaphthyridines | |
| EP0442511A3 (en) | Allen-key | |
| EP0444458A3 (en) | Pulsdopplerradar | |
| EP0441276A3 (en) | Electrophotoreceptor | |
| DE4092685D2 (en) | Mehrkomponenten-kleb- und -werkstoffverarbeitungssystem | |
| EP0481219A3 (en) | Connection piece | |
| EP0439820A3 (en) | Vacuumswitch | |
| EP0442371A3 (en) | Bisglycosides | |
| AU110900S (en) | Facsimilie | |
| DE4191594D2 (en) | Sicherheitsgurtverschluss | |
| AU109294S (en) | Listello | |
| CA65360S (en) | Stomatologic electroanesthetizer |