NO924326D0 - Antitrombosemidler - Google Patents

Antitrombosemidler

Info

Publication number
NO924326D0
NO924326D0 NO924326A NO924326A NO924326D0 NO 924326 D0 NO924326 D0 NO 924326D0 NO 924326 A NO924326 A NO 924326A NO 924326 A NO924326 A NO 924326A NO 924326 D0 NO924326 D0 NO 924326D0
Authority
NO
Norway
Prior art keywords
antitrombosemidler
Prior art date
Application number
NO924326A
Other languages
English (en)
Other versions
NO924326L (no
Inventor
Robert Theodore Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US79088591A priority Critical
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO924326D0 publication Critical patent/NO924326D0/no
Publication of NO924326L publication Critical patent/NO924326L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
NO92924326A 1991-11-12 1992-11-10 Antitrombosemidler NO924326L (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US79088591A true 1991-11-12 1991-11-12

Publications (2)

Publication Number Publication Date
NO924326D0 true NO924326D0 (no) 1992-11-10
NO924326L NO924326L (no) 1993-05-14

Family

ID=25152024

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92924326A NO924326L (no) 1991-11-12 1992-11-10 Antitrombosemidler

Country Status (19)

Country Link
EP (1) EP0542525B1 (no)
JP (1) JP3159806B2 (no)
KR (1) KR930009993A (no)
CN (1) CN1074438A (no)
AU (2) AU646767B2 (no)
BR (1) BR9204361A (no)
CA (1) CA2082748A1 (no)
CZ (1) CZ333492A3 (no)
DE (1) DE69226152T2 (no)
ES (1) ES2120993T3 (no)
FI (1) FI925124A (no)
HU (1) HUT65858A (no)
IL (1) IL103692D0 (no)
MX (1) MX9206474A (no)
NO (1) NO924326L (no)
NZ (1) NZ245039A (no)
TW (1) TW232686B (no)
YU (1) YU97292A (no)
ZA (1) ZA9208581B (no)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab NEW PEPTIDE DERIVATIVES
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra NEW PEPTIDES DERIVATIVES
US5780631A (en) * 1993-06-03 1998-07-14 Astra Aktiebolag Starting materials in the synthesis of thrombin and kininogenase inhibitors
US6984627B1 (en) 1993-06-03 2006-01-10 Astrazeneca Ab Peptide derivatives
ZA9501618B (en) * 1994-03-04 1996-08-27 Lilly Co Eli Antithrombotic agents
US5726159A (en) * 1994-03-04 1998-03-10 Eli Lilly And Company Antithrombotic agents
US5484772A (en) * 1994-03-04 1996-01-16 Eli Lilly And Company Antithrombotic agents
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
US5707966A (en) * 1994-03-04 1998-01-13 Eli Lilly And Company Antithrombotic agents
ZA9501617B (en) * 1994-03-04 1997-02-27 Lilly Co Eli Antithrombotic agents.
US5488037A (en) * 1994-03-04 1996-01-30 Eli Lilly And Company Antithrombotic agents
US5439888A (en) * 1994-03-04 1995-08-08 Eli Lilly And Company Antithrombotic agents
US5602101A (en) * 1994-03-04 1997-02-11 Eli Lilly And Company Antithrombotic agents
CA2143533A1 (en) * 1994-03-04 1995-09-05 Kenneth D. Kurz Antithrombotic agents
EP0748333A4 (en) * 1994-03-04 2000-05-10 Lilly Co Eli Antithrombotic agents
US5885967A (en) * 1994-03-04 1999-03-23 Eli Lilly And Company Antithrombotic agents
US5710130A (en) * 1995-02-27 1998-01-20 Eli Lilly And Company Antithrombotic agents
US5436229A (en) * 1994-03-04 1995-07-25 Eli Lilly And Company Bisulfite adducts of arginine aldehydes
US5914319A (en) * 1995-02-27 1999-06-22 Eli Lilly And Company Antithrombotic agents
DE4421052A1 (de) 1994-06-17 1995-12-21 Basf Ag Neue Thrombininhibitoren, ihre Herstellung und Verwendung
SE9404196D0 (sv) * 1994-12-02 1994-12-02 Astra Ab New antithrombotic formulation
EA199700186A1 (ru) * 1995-02-17 1998-02-26 Басф Акциенгезельшафт Новые дипептидные амидины, используемые в качестве ингибиторов тромбина
SA96170106A (ar) 1995-07-06 2005-12-03 أسترا أكتيبولاج مشتقات حامض أميني جديدة
TWI238827B (en) 1995-12-21 2005-09-01 Astrazeneca Ab Prodrugs of thrombin inhibitors
SE9602263D0 (sv) 1996-06-07 1996-06-07 Astra Ab New amino acid derivatives
SE9602646D0 (sv) 1996-07-04 1996-07-04 Astra Ab Pharmaceutically useful compounds
CA2289625A1 (en) 1997-05-15 1998-11-19 Charles Van Jackson Antithrombotic compound
AR013084A1 (es) 1997-06-19 2000-12-13 Astrazeneca Ab Derivados de amidino utiles como inhibidores de la trombina, composicion farmaceutica, utilizacion de dichos compuestos para la preparacion demedicamentos y proceso para la preparacion de los compuestos mencionados
SE9704543D0 (sv) 1997-12-05 1997-12-05 Astra Ab New compounds
JP2002501081A (ja) 1998-01-26 2002-01-15 ビーエーエスエフ アクチェンゲゼルシャフト トロンビンインヒビター
SE9804313D0 (sv) 1998-12-14 1998-12-14 Astra Ab New compounds
AU764121B2 (en) 1999-01-13 2003-08-07 Astrazeneca Ab New amidinobenzylamine derivatives and their use as thrombin inhibitors
AR023510A1 (es) 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
DE60103959T2 (de) 2000-04-19 2005-07-07 Kaneka Corp. Neue azetidin-derivate und ein verfahren zur herstellung derselben
SE0001803D0 (sv) 2000-05-16 2000-05-16 Astrazeneca Ab New compounds i
US6433186B1 (en) 2000-08-16 2002-08-13 Astrazeneca Ab Amidino derivatives and their use as thormbin inhibitors
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
AR035216A1 (es) 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
AR034517A1 (es) 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
US7781424B2 (en) 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
SE0201659D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
US7795205B2 (en) 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
EP1996186A4 (en) * 2006-03-06 2009-07-22 Humagene Inc A method for the preparation of recombinant human thrombin and fibrinogen
CN101190895B (zh) * 2006-11-30 2010-05-26 首都医科大学 N-[(3s)-1,2,3,4-四氢异喹啉-3-甲酰基]氨基酸、其制备方法及应用
TW200827336A (en) 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
CN101318933B (zh) * 2007-06-04 2010-08-11 北京大学 具有抗血栓活性的异喹啉化合物、其制备方法及应用
CN102127097A (zh) * 2010-01-15 2011-07-20 首都医科大学 N-(3s-1,2,3,4-四氢异喹啉-3-甲酰基)氨基酸铜络合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318904A (en) * 1980-04-25 1982-03-09 Research Corporation Peptide affinity labels for thrombin and other trypsin-like proteases
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
SE9102462D0 (sv) * 1991-08-28 1991-08-28 Astra Ab NEW ISOSTERIC PEPTIDES

Also Published As

Publication number Publication date
DE69226152T2 (de) 1998-12-10
KR930009993A (ko) 1993-06-21
AU2831292A (en) 1993-05-13
HU9203545D0 (en) 1993-01-28
CZ333492A3 (en) 1993-09-15
CN1074438A (zh) 1993-07-21
BR9204361A (pt) 1993-06-01
NO924326L (no) 1993-05-14
CA2082748A1 (en) 1993-05-13
FI925124A (fi) 1993-05-13
ES2120993T3 (es) 1998-11-16
IL103692D0 (en) 1993-04-04
FI925124A0 (fi) 1992-11-11
ZA9208581B (en) 1994-05-06
HUT65858A (en) 1994-07-28
NZ245039A (en) 1994-12-22
DE69226152D1 (de) 1998-08-13
FI925124D0 (no)
EP0542525B1 (en) 1998-07-08
AU2829892A (en) 1993-05-13
MX9206474A (es) 1993-10-01
TW232686B (no) 1994-10-21
EP0542525A3 (en) 1994-06-29
AU646767B2 (en) 1994-03-03
EP0542525A2 (en) 1993-05-19
JP3159806B2 (ja) 2001-04-23
YU97292A (sh) 1995-10-24
JPH05221964A (ja) 1993-08-31

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