IL103545A0 - 2-aminomethyl-chromans,their preparation and pharmaceutical compositions containing them - Google Patents

2-aminomethyl-chromans,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL103545A0
IL103545A0 IL103545A IL10354592A IL103545A0 IL 103545 A0 IL103545 A0 IL 103545A0 IL 103545 A IL103545 A IL 103545A IL 10354592 A IL10354592 A IL 10354592A IL 103545 A0 IL103545 A0 IL 103545A0
Authority
IL
Israel
Prior art keywords
chromans
aminomethyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL103545A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL103545A0 publication Critical patent/IL103545A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL103545A 1991-10-28 1992-10-26 2-aminomethyl-chromans,their preparation and pharmaceutical compositions containing them IL103545A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4135474A DE4135474A1 (de) 1991-10-28 1991-10-28 2-aminomethyl-chromane

Publications (1)

Publication Number Publication Date
IL103545A0 true IL103545A0 (en) 1993-03-15

Family

ID=6443566

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103545A IL103545A0 (en) 1991-10-28 1992-10-26 2-aminomethyl-chromans,their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (3) US5318988A (enExample)
EP (1) EP0540914B1 (enExample)
JP (1) JP3299321B2 (enExample)
KR (1) KR930007930A (enExample)
AT (1) ATE180777T1 (enExample)
AU (1) AU2626492A (enExample)
CA (1) CA2081300A1 (enExample)
CZ (1) CZ322592A3 (enExample)
DE (2) DE4135474A1 (enExample)
ES (1) ES2132105T3 (enExample)
FI (1) FI924847A7 (enExample)
HU (1) HUT62875A (enExample)
IL (1) IL103545A0 (enExample)
MX (1) MX9205681A (enExample)
NO (1) NO923975L (enExample)
TW (1) TW207537B (enExample)
ZA (1) ZA928291B (enExample)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
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DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
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US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
US5684039A (en) * 1995-07-25 1997-11-04 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5670667A (en) * 1995-07-25 1997-09-23 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5663194A (en) * 1995-07-25 1997-09-02 Mewshaw; Richard E. Chroman-2-ylmethylamino derivatives
AR004523A1 (es) * 1995-11-06 1998-12-16 American Home Prod 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
US5756532A (en) 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
ES2196312T3 (es) * 1996-10-15 2003-12-16 Wyeth Corp Derivados azaheterociclimetilo de 3,3,9 -tetrahidro-7h 1,4-dioxino (2,3-4) indol-8-0na.
US5869490A (en) * 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
US5750556A (en) * 1996-10-30 1998-05-12 American Home Products Corporation 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
EE200000055A (et) 1997-07-31 2000-10-16 Dupont Pharmaceuticals Company Protsess tsüklopropüülatsetüleeni valmistamiseks
UA58476C2 (uk) * 1997-10-09 2003-08-15 Санофі-Сентелябо Похідні 8-азабіцикло[3.2.1]октан-3-метанаміну, фармацевтична композиція та лікарський засіб
FR2769629B1 (fr) * 1997-10-09 1999-11-12 Synthelabo Derives de 8-azabicyclo[3.2.1]octane-3-methanamine, leur preparation et leur application en therapeutique
DE19751949A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
DE19754573A1 (de) * 1997-12-09 1999-06-10 Bayer Ag Pharmazeutische Zusammensetzung zur Behandlung von Schlaganfall und Schädel-Hirn-Trauma
US6235957B1 (en) 1998-06-29 2001-05-22 Dupont Pharmaceuticals Company Process for the preparation of cyclopropylacetylene
US6288297B1 (en) 1998-10-01 2001-09-11 Dupont Pharmaceuticals Company Process for the preparation of cyclopropylacetylene
US6359164B1 (en) 1998-10-01 2002-03-19 Zhe Wang Process for the preparation of cyclopropylacetylene
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US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
US6458802B1 (en) 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
US6803368B2 (en) 2001-04-25 2004-10-12 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
US6627639B2 (en) 2001-04-26 2003-09-30 Wyeth Uses for indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino-[2,3-e]indole
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US6861427B2 (en) * 2001-04-26 2005-03-01 Wyeth Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists
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US6800641B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene
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US6861434B2 (en) 2001-04-26 2005-03-01 Wyeth Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one
US6706736B2 (en) 2001-04-26 2004-03-16 Wyeth Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans
MXPA03009826A (es) 2001-04-26 2005-03-07 Wyeth Corp Azaheterociclilmetil derivados de 2,3-dihidro-1,4-dioxino[2,3-f]quinoxalina como agentes antidepresivos.
DE10120619A1 (de) * 2001-04-26 2002-10-31 Merck Patent Gmbh 2-(5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl-chroman
US6800642B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
US6593350B2 (en) 2001-04-26 2003-07-15 Wyeth Antidepressant indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino[2,3-e]indole
US7008944B2 (en) * 2001-04-26 2006-03-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
US6927226B2 (en) * 2001-04-26 2005-08-09 Wyeth Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
US6617334B2 (en) 2001-04-30 2003-09-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
US6555560B2 (en) 2001-04-30 2003-04-29 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
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US6906206B2 (en) * 2001-04-30 2005-06-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6815448B2 (en) 2001-05-07 2004-11-09 Wyeth Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
BR0209901A (pt) * 2001-05-17 2004-07-13 Wyeth Corp Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina
US6541502B1 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) * 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6903110B2 (en) 2001-07-25 2005-06-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene
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DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane

Also Published As

Publication number Publication date
EP0540914A1 (de) 1993-05-12
KR930007930A (ko) 1993-05-20
TW207537B (enExample) 1993-06-11
FI924847L (fi) 1993-04-29
ATE180777T1 (de) 1999-06-15
NO923975D0 (no) 1992-10-13
JP3299321B2 (ja) 2002-07-08
HU9203383D0 (en) 1993-01-28
DE59209704D1 (de) 1999-07-08
JPH05194473A (ja) 1993-08-03
HUT62875A (en) 1993-06-28
ZA928291B (en) 1993-05-06
US5318988A (en) 1994-06-07
EP0540914B1 (de) 1999-06-02
DE4135474A1 (de) 1993-04-29
ES2132105T3 (es) 1999-08-16
US5962513A (en) 1999-10-05
MX9205681A (es) 1993-04-01
NO923975L (no) 1993-04-29
CZ322592A3 (en) 1993-05-12
AU2626492A (en) 1993-04-29
FI924847A0 (fi) 1992-10-26
CA2081300A1 (en) 1993-04-29
FI924847A7 (fi) 1993-04-29
US5468882A (en) 1995-11-21

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