AU2626492A - 2- aminomethyl-chromans - Google Patents

2- aminomethyl-chromans

Info

Publication number
AU2626492A
AU2626492A AU26264/92A AU2626492A AU2626492A AU 2626492 A AU2626492 A AU 2626492A AU 26264/92 A AU26264/92 A AU 26264/92A AU 2626492 A AU2626492 A AU 2626492A AU 2626492 A AU2626492 A AU 2626492A
Authority
AU
Australia
Prior art keywords
chromans
aminomethyl
aminomethylchromans
correspondingly substituted
alkylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU26264/92A
Other languages
English (en)
Inventor
Wolfgang Dr. Dompert
Thomas Dr. Glaser
Hans-Georg Dr. Heine
Bodo Dr. Junge
Rudolf Dr. Schohe-Loop
Henning Dr. Sommermeyer
Jean Marie Dr. Viktor De Vry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2626492A publication Critical patent/AU2626492A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/64—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with oxygen atoms directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU26264/92A 1991-10-28 1992-10-07 2- aminomethyl-chromans Abandoned AU2626492A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4135474 1991-10-28
DE4135474A DE4135474A1 (de) 1991-10-28 1991-10-28 2-aminomethyl-chromane

Publications (1)

Publication Number Publication Date
AU2626492A true AU2626492A (en) 1993-04-29

Family

ID=6443566

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26264/92A Abandoned AU2626492A (en) 1991-10-28 1992-10-07 2- aminomethyl-chromans

Country Status (17)

Country Link
US (3) US5318988A (enExample)
EP (1) EP0540914B1 (enExample)
JP (1) JP3299321B2 (enExample)
KR (1) KR930007930A (enExample)
AT (1) ATE180777T1 (enExample)
AU (1) AU2626492A (enExample)
CA (1) CA2081300A1 (enExample)
CZ (1) CZ322592A3 (enExample)
DE (2) DE4135474A1 (enExample)
ES (1) ES2132105T3 (enExample)
FI (1) FI924847A7 (enExample)
HU (1) HUT62875A (enExample)
IL (1) IL103545A0 (enExample)
MX (1) MX9205681A (enExample)
NO (1) NO923975L (enExample)
TW (1) TW207537B (enExample)
ZA (1) ZA928291B (enExample)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
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DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
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DE69524528T2 (de) * 1994-10-14 2002-08-01 Merck Patent Gmbh ZNS wirksames (R)-(-)-2-[5-(4-Fluorophenyl)-3-pyridylmethylaminomethyl]chroman
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
US5684039A (en) * 1995-07-25 1997-11-04 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5670667A (en) * 1995-07-25 1997-09-23 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5663194A (en) * 1995-07-25 1997-09-02 Mewshaw; Richard E. Chroman-2-ylmethylamino derivatives
US5756532A (en) * 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
IL119483A (en) * 1995-11-06 1999-06-20 American Home Prod 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
EP0932609B1 (en) * 1996-10-15 2003-05-14 Wyeth AZAHETEROCYCLYMETHYL DERIVATIVES OF 2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO 2,3-e]INDOL-8-ONE
US5869490A (en) * 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
US5750556A (en) * 1996-10-30 1998-05-12 American Home Products Corporation 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
BR9810842A (pt) * 1997-07-31 2000-07-25 Du Pont Pharm Co Processo para a sìntese de ciclopropilacetileno e composto
UA58476C2 (uk) * 1997-10-09 2003-08-15 Санофі-Сентелябо Похідні 8-азабіцикло[3.2.1]октан-3-метанаміну, фармацевтична композиція та лікарський засіб
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DE19754573A1 (de) * 1997-12-09 1999-06-10 Bayer Ag Pharmazeutische Zusammensetzung zur Behandlung von Schlaganfall und Schädel-Hirn-Trauma
US6235957B1 (en) 1998-06-29 2001-05-22 Dupont Pharmaceuticals Company Process for the preparation of cyclopropylacetylene
US6288297B1 (en) 1998-10-01 2001-09-11 Dupont Pharmaceuticals Company Process for the preparation of cyclopropylacetylene
US6359164B1 (en) 1998-10-01 2002-03-19 Zhe Wang Process for the preparation of cyclopropylacetylene
DE19858341A1 (de) * 1998-12-17 2000-06-21 Merck Patent Gmbh Chromanderivate
UA73981C2 (en) 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
US6458802B1 (en) 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
US6803368B2 (en) 2001-04-25 2004-10-12 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
US6800648B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one
US6627639B2 (en) 2001-04-26 2003-09-30 Wyeth Uses for indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino-[2,3-e]indole
DE10120619A1 (de) * 2001-04-26 2002-10-31 Merck Patent Gmbh 2-(5-(4-Fluorphenyl)-3-pyridylmethylaminomethyl-chroman
US6593350B2 (en) 2001-04-26 2003-07-15 Wyeth Antidepressant indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino[2,3-e]indole
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US6800641B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene
EP1381612A1 (en) 2001-04-26 2004-01-21 Wyeth Antidepressant aza-heterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinazoline
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US6706736B2 (en) 2001-04-26 2004-03-16 Wyeth Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans
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US6800642B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
WO2002088132A1 (en) 2001-04-26 2002-11-07 Wyeth Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists
DK1401839T5 (da) 2001-04-26 2006-03-13 Wyeth Corp Antidepressive (SSSRI) azaheterocyclylmethylderivater af 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalen
US6927226B2 (en) * 2001-04-26 2005-08-09 Wyeth Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
US6555560B2 (en) 2001-04-30 2003-04-29 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6617334B2 (en) 2001-04-30 2003-09-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
CA2445859A1 (en) 2001-04-30 2002-11-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
US6906206B2 (en) * 2001-04-30 2005-06-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6815448B2 (en) 2001-05-07 2004-11-09 Wyeth Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
MXPA03010524A (es) * 2001-05-17 2005-03-07 Wyeth Corp Proceso para la sintesis de derivados de la 2,3-dihidro-1,4-dioxino-[2,3-f]-quinolina.
US6541502B1 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
AR035083A1 (es) * 2001-07-25 2004-04-14 Wyeth Corp Derivados azaheterociclilmetilicos de 7,8-dihidro-6h-5-oxa-1-aza-fenantreno, composiciones farmaceuticas, el uso de dichos derivados para la preparacion de un medicamento antidepresivo e intermediarios
ATE352302T1 (de) 2001-07-26 2007-02-15 Merck Patent Gmbh Verwendung von 2- 5-(4-fluorphenyl)-3- pyridylmethylaminomethyl-chroman und seiner physiologisch annehmbaren salze
DE60211186T2 (de) * 2001-09-19 2007-01-18 Merck Patent Gmbh Neue verwendung substituierter aminomethylchromane
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CN1561338A (zh) * 2001-10-04 2005-01-05 惠氏公司 作为5－羟基色胺－6配体的苯并二氢吡喃衍生物
JP2005510480A (ja) 2001-10-05 2005-04-21 ワイス ２−ヒドロキシメチル−クロマンの立体選択的合成方法
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US8492372B2 (en) * 2008-04-29 2013-07-23 Integrated Research Laboratories Sweden Ab Modulators of dopamine neurotransmission
JP5514804B2 (ja) * 2008-04-29 2014-06-04 エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ ドーパミン神経伝達のモジュレーター
CN102575029B (zh) * 2009-09-02 2014-10-15 纳幕尔杜邦公司 具有改善的拒油性的聚酯膜
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KR20120070579A (ko) * 2009-09-02 2012-06-29 이 아이 듀폰 디 네모아 앤드 캄파니 플루오로에테르 작용화된 방향족 다이에스테르 및 그 유도체
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Also Published As

Publication number Publication date
CA2081300A1 (en) 1993-04-29
FI924847L (fi) 1993-04-29
IL103545A0 (en) 1993-03-15
DE59209704D1 (de) 1999-07-08
JPH05194473A (ja) 1993-08-03
JP3299321B2 (ja) 2002-07-08
NO923975D0 (no) 1992-10-13
US5468882A (en) 1995-11-21
EP0540914A1 (de) 1993-05-12
FI924847A7 (fi) 1993-04-29
CZ322592A3 (en) 1993-05-12
EP0540914B1 (de) 1999-06-02
DE4135474A1 (de) 1993-04-29
HU9203383D0 (en) 1993-01-28
US5318988A (en) 1994-06-07
ZA928291B (en) 1993-05-06
FI924847A0 (fi) 1992-10-26
NO923975L (no) 1993-04-29
TW207537B (enExample) 1993-06-11
ATE180777T1 (de) 1999-06-15
MX9205681A (es) 1993-04-01
ES2132105T3 (es) 1999-08-16
US5962513A (en) 1999-10-05
KR930007930A (ko) 1993-05-20
HUT62875A (en) 1993-06-28

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