IL101117A - Production of attack-resistant plants SCLEROTINIA SCLEROTIORUM by introducing a gene that encodes oxalate oxidase - Google Patents
Production of attack-resistant plants SCLEROTINIA SCLEROTIORUM by introducing a gene that encodes oxalate oxidaseInfo
- Publication number
- IL101117A IL101117A IL10111792A IL10111792A IL101117A IL 101117 A IL101117 A IL 101117A IL 10111792 A IL10111792 A IL 10111792A IL 10111792 A IL10111792 A IL 10111792A IL 101117 A IL101117 A IL 101117A
- Authority
- IL
- Israel
- Prior art keywords
- oxalate oxidase
- plant
- chimeric gene
- ssu
- plants
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 67
- 108010063734 Oxalate oxidase Proteins 0.000 title claims abstract description 25
- 241000221696 Sclerotinia sclerotiorum Species 0.000 title description 8
- 238000004519 manufacturing process Methods 0.000 title description 4
- 206010034133 Pathogen resistance Diseases 0.000 claims abstract 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract 3
- 241000196324 Embryophyta Species 0.000 claims description 29
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 25
- 102000004169 proteins and genes Human genes 0.000 claims description 21
- 235000003222 Helianthus annuus Nutrition 0.000 claims description 14
- 239000013598 vector Substances 0.000 claims description 9
- 235000006008 Brassica napus var napus Nutrition 0.000 claims description 7
- 108010076504 Protein Sorting Signals Proteins 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 6
- 230000001131 transforming effect Effects 0.000 claims description 3
- YAHZABJORDUQGO-NQXXGFSBSA-N D-ribulose 1,5-bisphosphate Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)C(=O)COP(O)(O)=O YAHZABJORDUQGO-NQXXGFSBSA-N 0.000 claims description 2
- 244000020551 Helianthus annuus Species 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 241001233957 eudicotyledons Species 0.000 claims description 2
- 240000000385 Brassica napus var. napus Species 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 235000019833 protease Nutrition 0.000 claims 1
- 108010003581 Ribulose-bisphosphate carboxylase Proteins 0.000 description 34
- 108090000765 processed proteins & peptides Proteins 0.000 description 29
- 240000008042 Zea mays Species 0.000 description 25
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 25
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 25
- 235000009973 maize Nutrition 0.000 description 25
- 239000012634 fragment Substances 0.000 description 22
- 241001167018 Aroa Species 0.000 description 14
- 150000001413 amino acids Chemical class 0.000 description 14
- 239000002299 complementary DNA Substances 0.000 description 14
- 241000208818 Helianthus Species 0.000 description 12
- 230000004927 fusion Effects 0.000 description 12
- 239000013612 plasmid Substances 0.000 description 11
- 235000006408 oxalic acid Nutrition 0.000 description 8
- 241000233866 Fungi Species 0.000 description 7
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- 244000060924 Brassica campestris Species 0.000 description 4
- 240000002791 Brassica napus Species 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 239000002773 nucleotide Substances 0.000 description 4
- 125000003729 nucleotide group Chemical group 0.000 description 4
- PHOLIFLKGONSGY-CSKARUKUSA-N (e)-(3-methyl-1,3-benzothiazol-2-ylidene)hydrazine Chemical compound C1=CC=C2S\C(=N\N)N(C)C2=C1 PHOLIFLKGONSGY-CSKARUKUSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000003776 cleavage reaction Methods 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 230000002101 lytic effect Effects 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000008929 regeneration Effects 0.000 description 3
- 238000011069 regeneration method Methods 0.000 description 3
- 230000007017 scission Effects 0.000 description 3
- 238000012163 sequencing technique Methods 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- 108020004705 Codon Proteins 0.000 description 2
- 101150111720 EPSPS gene Proteins 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000007918 pathogenicity Effects 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 230000002103 transcriptional effect Effects 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- 108010020183 3-phosphoshikimate 1-carboxyvinyltransferase Proteins 0.000 description 1
- QZHXKQKKEBXYRG-UHFFFAOYSA-N 4-n-(4-aminophenyl)benzene-1,4-diamine Chemical compound C1=CC(N)=CC=C1NC1=CC=C(N)C=C1 QZHXKQKKEBXYRG-UHFFFAOYSA-N 0.000 description 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- 241000589158 Agrobacterium Species 0.000 description 1
- 241000589155 Agrobacterium tumefaciens Species 0.000 description 1
- 241000131317 Capitulum Species 0.000 description 1
- 241000701489 Cauliflower mosaic virus Species 0.000 description 1
- ZAQJHHRNXZUBTE-NQXXGFSBSA-N D-ribulose Chemical compound OC[C@@H](O)[C@@H](O)C(=O)CO ZAQJHHRNXZUBTE-NQXXGFSBSA-N 0.000 description 1
- ZAQJHHRNXZUBTE-UHFFFAOYSA-N D-threo-2-Pentulose Natural products OCC(O)C(O)C(=O)CO ZAQJHHRNXZUBTE-UHFFFAOYSA-N 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 241000701533 Escherichia virus T4 Species 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 241000209510 Liliopsida Species 0.000 description 1
- 108700026244 Open Reading Frames Proteins 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 108091081024 Start codon Proteins 0.000 description 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
- 239000004473 Threonine Substances 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 231100001222 nononcogenic Toxicity 0.000 description 1
- 108010058731 nopaline synthase Proteins 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/03—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with oxygen as acceptor (1.2.3)
- C12Y102/03004—Oxalate oxidase (1.2.3.4)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Environmental Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Virology (AREA)
- Dentistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Networks Using Active Elements (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9102874A FR2673644A1 (fr) | 1991-03-05 | 1991-03-05 | Sequence adn codant pour une oxalate oxydase et plantes transformees contenant cette sequence et resistantes au sclerotinia. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL101117A0 IL101117A0 (en) | 1992-11-15 |
IL101117A true IL101117A (en) | 2004-09-27 |
Family
ID=9410559
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10111792A IL101117A (en) | 1991-03-05 | 1992-03-02 | Production of attack-resistant plants SCLEROTINIA SCLEROTIORUM by introducing a gene that encodes oxalate oxidase |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0531498B1 (xx) |
JP (1) | JPH05506582A (xx) |
KR (1) | KR930700665A (xx) |
CN (1) | CN1051576C (xx) |
AT (1) | ATE338129T1 (xx) |
AU (1) | AU660976B2 (xx) |
BG (1) | BG61275B1 (xx) |
BR (1) | BR9204788A (xx) |
CA (1) | CA2082042C (xx) |
CZ (1) | CZ289623B6 (xx) |
DE (1) | DE69233653T2 (xx) |
DK (1) | DK0531498T3 (xx) |
EG (1) | EG21465A (xx) |
ES (1) | ES2273329T3 (xx) |
FR (1) | FR2673644A1 (xx) |
HU (1) | HUT65677A (xx) |
IE (1) | IE920691A1 (xx) |
IL (1) | IL101117A (xx) |
MX (1) | MX9200917A (xx) |
NZ (1) | NZ241829A (xx) |
PT (1) | PT100203B (xx) |
UA (1) | UA43308C2 (xx) |
WO (1) | WO1992015685A1 (xx) |
ZA (1) | ZA921647B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU214357B (hu) * | 1991-02-25 | 1998-03-30 | Zeneca Ltd. | Készítmény és eljárás oxálsav lebontására és az oxalátok mennyiségének csökkentésére növényekben, és eljárás növények védelmére oxálsavat kiválasztó gombákkal szemben |
RO112764B1 (ro) * | 1992-11-30 | 1997-12-30 | Zeneca Ltd | Secventa adn ce codifica oxalat decarboxilaza |
AU5653294A (en) * | 1992-12-07 | 1994-07-04 | Elf Aquitaine | Use of a dna sequence coding for an oxalic acid degrading protein as a selection gene |
AUPM379294A0 (en) * | 1994-02-10 | 1994-03-03 | Commonwealth Scientific And Industrial Research Organisation | Expression of the glucose oxidase gene in transgenic organisms |
US6166291A (en) | 1997-07-18 | 2000-12-26 | Pioneer Hi-Bred International, Inc. | Production of pathogen resistant plants |
ZA986308B (en) * | 1997-07-18 | 1999-11-24 | Pioneer Hi Bred Int | The induction of stress-related factors in plants. |
AU8919098A (en) * | 1997-08-26 | 1999-03-16 | North Carolina State University | Fumonosin resistance |
FR2844142B1 (fr) | 2002-09-11 | 2007-08-17 | Bayer Cropscience Sa | Plantes transformees a biosynthese de prenylquinones amelioree |
FR2848570B1 (fr) | 2002-12-12 | 2005-04-01 | Bayer Cropscience Sa | Cassette d'expression codant pour une 5-enol pyruvylshikimate-3-phosphate synthase (epsps) et plantes tolerantes aux herbicides la contenant |
CN100383239C (zh) * | 2004-07-21 | 2008-04-23 | 华南农业大学 | 从小麦麸皮中提取草酸氧化酶的方法 |
AR074941A1 (es) | 2009-01-07 | 2011-02-23 | Bayer Cropscience Sa | Plantas transplastomicas exentas de marcador de seleccion |
CA2786001A1 (en) | 2009-12-31 | 2011-07-07 | Pioneer Hi-Bred International, Inc. | Engineering plant resistance to diseases caused by pathogens |
CN103060350A (zh) * | 2011-10-21 | 2013-04-24 | 华中农业大学 | 核盘菌草酸脱羧酶基因SsOXDC2及其在大豆抗病改良中的应用 |
CN103911384B (zh) * | 2014-01-21 | 2016-05-25 | 江苏大学 | 一种控制油菜菌核病的基因及其应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988008450A1 (en) * | 1987-05-01 | 1988-11-03 | Birdwell Finlayson | Gene therapy for metabolite disorders |
HU214357B (hu) * | 1991-02-25 | 1998-03-30 | Zeneca Ltd. | Készítmény és eljárás oxálsav lebontására és az oxalátok mennyiségének csökkentésére növényekben, és eljárás növények védelmére oxálsavat kiválasztó gombákkal szemben |
-
1991
- 1991-03-05 FR FR9102874A patent/FR2673644A1/fr active Granted
-
1992
- 1992-02-28 CN CN92101989A patent/CN1051576C/zh not_active Expired - Lifetime
- 1992-03-02 IL IL10111792A patent/IL101117A/en not_active IP Right Cessation
- 1992-03-03 MX MX9200917A patent/MX9200917A/es unknown
- 1992-03-03 EG EG12792A patent/EG21465A/xx active
- 1992-03-04 UA UA93004232A patent/UA43308C2/uk unknown
- 1992-03-04 AU AU16820/92A patent/AU660976B2/en not_active Expired
- 1992-03-04 JP JP92507499A patent/JPH05506582A/ja active Pending
- 1992-03-04 AT AT92908073T patent/ATE338129T1/de not_active IP Right Cessation
- 1992-03-04 KR KR1019920702749A patent/KR930700665A/ko not_active Application Discontinuation
- 1992-03-04 ES ES92908073T patent/ES2273329T3/es not_active Expired - Lifetime
- 1992-03-04 CA CA002082042A patent/CA2082042C/en not_active Expired - Lifetime
- 1992-03-04 NZ NZ241829A patent/NZ241829A/xx not_active IP Right Cessation
- 1992-03-04 BR BR9204788A patent/BR9204788A/pt not_active Application Discontinuation
- 1992-03-04 CZ CS19923369A patent/CZ289623B6/cs not_active IP Right Cessation
- 1992-03-04 WO PCT/FR1992/000195 patent/WO1992015685A1/fr active IP Right Grant
- 1992-03-04 DE DE69233653T patent/DE69233653T2/de not_active Expired - Lifetime
- 1992-03-04 DK DK92908073T patent/DK0531498T3/da active
- 1992-03-04 IE IE069192A patent/IE920691A1/en unknown
- 1992-03-04 HU HU9203473A patent/HUT65677A/hu unknown
- 1992-03-04 EP EP92908073A patent/EP0531498B1/fr not_active Expired - Lifetime
- 1992-03-05 PT PT100203A patent/PT100203B/pt not_active IP Right Cessation
- 1992-03-05 ZA ZA921647A patent/ZA921647B/xx unknown
- 1992-11-03 BG BG97042A patent/BG61275B1/bg unknown
Also Published As
Publication number | Publication date |
---|---|
IL101117A0 (en) | 1992-11-15 |
DE69233653D1 (de) | 2006-10-12 |
DK0531498T3 (da) | 2007-01-02 |
NZ241829A (en) | 1994-04-27 |
CZ289623B6 (cs) | 2002-03-13 |
DE69233653T2 (de) | 2007-10-04 |
BG61275B1 (en) | 1997-04-30 |
CN1051576C (zh) | 2000-04-19 |
ZA921647B (en) | 1992-11-25 |
AU1682092A (en) | 1992-10-06 |
MX9200917A (es) | 1992-11-01 |
EP0531498B1 (fr) | 2006-08-30 |
PT100203A (pt) | 1993-07-30 |
CA2082042C (en) | 2007-05-29 |
EP0531498A1 (fr) | 1993-03-17 |
BR9204788A (pt) | 1993-07-27 |
ATE338129T1 (de) | 2006-09-15 |
HU9203473D0 (en) | 1993-01-28 |
KR930700665A (ko) | 1993-03-15 |
FR2673644B1 (xx) | 1994-12-02 |
JPH05506582A (ja) | 1993-09-30 |
BG97042A (bg) | 1993-12-24 |
HUT65677A (en) | 1994-07-28 |
IE920691A1 (en) | 1992-09-09 |
CA2082042A1 (en) | 1992-09-06 |
WO1992015685A1 (fr) | 1992-09-17 |
AU660976B2 (en) | 1995-07-13 |
CN1065683A (zh) | 1992-10-28 |
UA43308C2 (uk) | 2001-12-17 |
FR2673644A1 (fr) | 1992-09-11 |
CZ336992A3 (en) | 1994-01-19 |
EG21465A (en) | 2001-11-28 |
PT100203B (pt) | 1999-06-30 |
ES2273329T3 (es) | 2007-05-01 |
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