IL100623A - PROCESS FOR THE PRODUCTION OF RECOMBINANT IgA PROTEASE AND THE IgA PROTEASE PRODUCED THEREBY - Google Patents

PROCESS FOR THE PRODUCTION OF RECOMBINANT IgA PROTEASE AND THE IgA PROTEASE PRODUCED THEREBY

Info

Publication number
IL100623A
IL100623A IL10062392A IL10062392A IL100623A IL 100623 A IL100623 A IL 100623A IL 10062392 A IL10062392 A IL 10062392A IL 10062392 A IL10062392 A IL 10062392A IL 100623 A IL100623 A IL 100623A
Authority
IL
Israel
Prior art keywords
iga protease
modified
iga
recombinant
gene
Prior art date
Application number
IL10062392A
Other languages
English (en)
Other versions
IL100623A0 (en
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of IL100623A0 publication Critical patent/IL100623A0/xx
Publication of IL100623A publication Critical patent/IL100623A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL10062392A 1991-01-11 1992-01-09 PROCESS FOR THE PRODUCTION OF RECOMBINANT IgA PROTEASE AND THE IgA PROTEASE PRODUCED THEREBY IL100623A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4100704 1991-01-11
DE4140699A DE4140699A1 (de) 1991-01-11 1991-12-10 Rekombinante iga-protease

Publications (2)

Publication Number Publication Date
IL100623A0 IL100623A0 (en) 1992-09-06
IL100623A true IL100623A (en) 2002-07-25

Family

ID=25900194

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10062392A IL100623A (en) 1991-01-11 1992-01-09 PROCESS FOR THE PRODUCTION OF RECOMBINANT IgA PROTEASE AND THE IgA PROTEASE PRODUCED THEREBY

Country Status (14)

Country Link
EP (1) EP0495398B1 (da)
JP (1) JP2509410B2 (da)
AT (1) ATE174627T1 (da)
AU (1) AU636261B2 (da)
CA (1) CA2058872C (da)
DE (2) DE4140699A1 (da)
DK (1) DK0495398T3 (da)
ES (1) ES2127732T3 (da)
FI (1) FI103132B (da)
HU (1) HU215188B (da)
IE (1) IE914559A1 (da)
IL (1) IL100623A (da)
NZ (1) NZ241280A (da)
TW (1) TW197470B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009395A2 (de) * 1994-09-21 1996-03-28 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Arzneimittel zur prophylaxe und behandlung von und diagnostika zur erkennung von autoimmunkrankheiten und viralen erkrankungen
GB9618960D0 (en) 1996-09-11 1996-10-23 Medical Science Sys Inc Proteases
AU9341398A (en) * 1997-08-22 1999-03-16 Boehringer Mannheim Gmbh Protease precursors that can be autocatalytically activated and their use
ATE294869T1 (de) * 1997-08-22 2005-05-15 Roche Diagnostics Gmbh Autokatalytisch aktivierbare zymogene vorstufen von proteasen und deren verwendung
AU7053500A (en) * 1999-09-15 2001-04-17 Eli Lilly And Company Chymotrypsin-free trypsin
US20100261252A1 (en) * 2009-04-10 2010-10-14 Biomarin Pharmaceutical Inc. Methods of enhancing yield of active iga protease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3622221A1 (de) * 1986-07-02 1988-01-14 Max Planck Gesellschaft Verfahren zur gentechnologischen gewinnung von proteinen unter verwendung gramnegativer wirtszellen
DE3832898A1 (de) * 1988-09-28 1990-04-12 Boehringer Mannheim Gmbh Praeparat von in prokaryonten exprimiertem plasminogenaktivator
DK130889A (da) * 1989-03-17 1990-09-18 Mogens Kilian Immunoglobulin a1-proteaser (iga1-proteaser), fremgangsmaade til genteknologisk fremstilling af saadanne enzymer samt vaccine indeholdende enzymerne og fragmenter deraf til immunisering mod bakteriel meningitis og andre sygdomme fremkaldt af iga1-protease-producerende bakterier

Also Published As

Publication number Publication date
DE4140699A1 (de) 1992-07-16
FI920117A (fi) 1992-07-12
IL100623A0 (en) 1992-09-06
DK0495398T3 (da) 1999-08-23
JP2509410B2 (ja) 1996-06-19
CA2058872A1 (en) 1992-07-12
ATE174627T1 (de) 1999-01-15
JPH05168478A (ja) 1993-07-02
IE914559A1 (en) 1992-07-15
FI920117A0 (fi) 1992-01-10
FI103132B1 (fi) 1999-04-30
TW197470B (da) 1993-01-01
AU636261B2 (en) 1993-04-22
EP0495398B1 (de) 1998-12-16
HU215188B (hu) 1998-10-28
AU9011691A (en) 1992-09-10
FI103132B (fi) 1999-04-30
HUT63654A (en) 1993-09-28
NZ241280A (en) 1993-10-26
DE59209590D1 (de) 1999-01-28
ES2127732T3 (es) 1999-05-01
EP0495398A1 (de) 1992-07-22
HU9200092D0 (en) 1992-03-30
CA2058872C (en) 1999-12-21

Similar Documents

Publication Publication Date Title
US5427927A (en) Process for the enzymatic cleavage of recombinant proteins using IgA proteases
EP0230869B1 (en) Construction of an igg binding protein to facilitate downstream processing using protein engineering
CN110551707A (zh) 一种纯化中性或碱性蛋白酶的方法
CA2058872C (en) Recombinant iga protease
US5082775A (en) Efficient process for isolating insoluble heterologous protein using non-ionic detergents
US5965424A (en) Methods for making neisseria or hemophilus IgA protease and DNA encoding the proteases
JP7449000B2 (ja) 可溶性の組換えタンパク質の生成
US6955910B2 (en) Method for large scale production of recombinant DNA-derived TPA or K2S molecules
JP2003512050A (ja) 組換え成熟型リソフスタフィンの発現
EP1981978B1 (en) Affinity polypeptide for purification of recombinant proteins
EP0312346B1 (en) E. coli sequence specific acid protease
JP2711148B2 (ja) ストレプトミセスからの遺伝子発現方法
KR100206731B1 (ko) 에리트리나 카프라 유래 재조합 억제인자를 이용한 세린 프로테아제의 정제방법
JP4651203B2 (ja) 新規グルタミナーゼ及びその製造方法
CA2185436C (en) Use of a recombinant inhibitor from erythrina caffra for purifying serine proteases
JP2003038171A (ja) 融合蛋白質より有用蛋白質を取得する方法
JPH03219892A (ja) タンパク質の製造法
JP2003024095A (ja) 融合蛋白質より有用蛋白質を取得する方法
JP2003024060A (ja) 融合蛋白質より有用蛋白質を取得する方法
JPH0588110B2 (da)
MXPA01009979A (en) Production of pancreatic procarboxy-peptidase b, isoforms and muteins thereof, and their use
JPS60145090A (ja) Dνa
JP2000083694A (ja) ポリペプチドの精製方法およびキット試薬

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees