NZ241280A - Recombinant iga protease with a modified non-functional c-terminal protein sequence - Google Patents

Recombinant iga protease with a modified non-functional c-terminal protein sequence

Info

Publication number
NZ241280A
NZ241280A NZ241280A NZ24128092A NZ241280A NZ 241280 A NZ241280 A NZ 241280A NZ 241280 A NZ241280 A NZ 241280A NZ 24128092 A NZ24128092 A NZ 24128092A NZ 241280 A NZ241280 A NZ 241280A
Authority
NZ
New Zealand
Prior art keywords
iga protease
functional
protein sequence
modified non
terminal protein
Prior art date
Application number
NZ241280A
Inventor
Dorothea Ambrosius
Carola Dony
Rainer Rudolph
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NZ241280A publication Critical patent/NZ241280A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Abstract

The present invention relates to a method for obtaining recombinant IgA protease from inclusion bodies. Also claimed is a recombinant DNA which codes for an IgA protease whose C-terminal helper portion and, preferably, also whose N-terminal signal portion is no longer active.
NZ241280A 1991-01-11 1992-01-10 Recombinant iga protease with a modified non-functional c-terminal protein sequence NZ241280A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4100704 1991-01-11
DE4140699A DE4140699A1 (en) 1991-01-11 1991-12-10 RECOMBINANT IGA PROTEASE

Publications (1)

Publication Number Publication Date
NZ241280A true NZ241280A (en) 1993-10-26

Family

ID=25900194

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ241280A NZ241280A (en) 1991-01-11 1992-01-10 Recombinant iga protease with a modified non-functional c-terminal protein sequence

Country Status (14)

Country Link
EP (1) EP0495398B1 (en)
JP (1) JP2509410B2 (en)
AT (1) ATE174627T1 (en)
AU (1) AU636261B2 (en)
CA (1) CA2058872C (en)
DE (2) DE4140699A1 (en)
DK (1) DK0495398T3 (en)
ES (1) ES2127732T3 (en)
FI (1) FI103132B1 (en)
HU (1) HU215188B (en)
IE (1) IE914559A1 (en)
IL (1) IL100623A (en)
NZ (1) NZ241280A (en)
TW (1) TW197470B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3651595A (en) * 1994-09-21 1996-04-09 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Drug for the prevention and treatment of auto-immune and viral diseases, and diagnostic agents for detecting said diseases
GB9618960D0 (en) 1996-09-11 1996-10-23 Medical Science Sys Inc Proteases
AU9260598A (en) * 1997-08-22 1999-03-16 Boehringer Mannheim Gmbh Zymogenic protease precursors that can be autocatalytically activated and their use
AU9341398A (en) * 1997-08-22 1999-03-16 Boehringer Mannheim Gmbh Protease precursors that can be autocatalytically activated and their use
WO2001019970A2 (en) * 1999-09-15 2001-03-22 Eli Lilly And Company Chymotrypsin-free trypsin
WO2010118337A2 (en) * 2009-04-10 2010-10-14 Biomarin Pharmaceutical Inc. Methods of enhancing yield of active iga protease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3622221A1 (en) * 1986-07-02 1988-01-14 Max Planck Gesellschaft METHOD FOR THE GENE-TECHNOLOGICAL EXTRACTION OF PROTEINS USING GRAM-NEGATIVE HOST CELLS
DE3832898A1 (en) * 1988-09-28 1990-04-12 Boehringer Mannheim Gmbh PRAEPARATE OF EXPRESSED PLASMINOGEN ACTIVATOR IN PROKARYONS
DK130889A (en) * 1989-03-17 1990-09-18 Mogens Kilian IMMUNOGLOBULIN A1 PROTEASES (IGA1 PROTASES), PROCEDURES FOR GENTECHNOLOGICAL PREPARATION OF SUCH ENZYMES, AND VACCINE-CONTAINING ENZYMES AND SYMBOLS OF PROMISTS OF BACKGROUND IMMUNISTRY AND BIT

Also Published As

Publication number Publication date
AU636261B2 (en) 1993-04-22
DE59209590D1 (en) 1999-01-28
TW197470B (en) 1993-01-01
HUT63654A (en) 1993-09-28
DE4140699A1 (en) 1992-07-16
FI103132B (en) 1999-04-30
DK0495398T3 (en) 1999-08-23
JP2509410B2 (en) 1996-06-19
IE914559A1 (en) 1992-07-15
HU215188B (en) 1998-10-28
AU9011691A (en) 1992-09-10
CA2058872C (en) 1999-12-21
HU9200092D0 (en) 1992-03-30
FI920117A0 (en) 1992-01-10
FI920117A (en) 1992-07-12
JPH05168478A (en) 1993-07-02
CA2058872A1 (en) 1992-07-12
FI103132B1 (en) 1999-04-30
EP0495398B1 (en) 1998-12-16
IL100623A (en) 2002-07-25
ATE174627T1 (en) 1999-01-15
ES2127732T3 (en) 1999-05-01
EP0495398A1 (en) 1992-07-22
IL100623A0 (en) 1992-09-06

Similar Documents

Publication Publication Date Title
DE60032367D1 (en) ACTIVE RECOMBINANT NEUROTOXINE
NO902082D0 (en) FIBRONECT BINING PROTEIN AND MANUFACTURING THEREOF.
KR840005739A (en) Method for isolating a gene encoding human relaxin and a method for producing a polypeptide having relaxin activity
AU1003888A (en) Pancreatic secretory trypsin inhibitor and variants thereof produced by a recombinant host, process, expression vector and recombinant host therefore and pharmaceutical use thereof
DE69715181T2 (en) PEPTIDE THE SOLUBLE FORM OF ACETYLCHOLINESTERASE WITH ACTIVITY AS A CALCIUM CHANNEL MODULATOR
NO882380D0 (en) FIBPHONECTIN BINDING PROTEIN, AND THE PREPARATION OF IT.
NZ241280A (en) Recombinant iga protease with a modified non-functional c-terminal protein sequence
ES2196019T3 (en) PROTEASA FUNGICA.
FI931634A0 (en) NYTT SVAMPPROTEAS
ATE170556T1 (en) DNA SEQUENCES, VECTORS AND FUSION POLYPEPTIDES FOR INCREASE SECRETION OF DESIRED POLYPEPTIDES FROM FILAMENTOUS FUNGI
ES2196048T3 (en) TOMATO ENDOTRANSGLYCOSILASE XYLOGLYCAN.
FI946076A (en) Modified Kluyveromyces yeasts, preparation and use
DE69737321D1 (en) POLYPEPTIDES OF HUMAN HYALURONAN SYNTHASE AND DNA THAT CODES THEREOF
NZ219611A (en) Insecticidal peptide produced by recombinant dna techniques
DE3825118A1 (en) Expression of the virally encoded protease P2A of HRV2
TH22943A (en) Recombinant, a protein defining DEV-1 useful for HIV detection, DNA sequencing, protein coding, and immunological analysis using this protein.

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired