IL100542A - Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones - Google Patents

Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones

Info

Publication number
IL100542A
IL100542A IL10054291A IL10054291A IL100542A IL 100542 A IL100542 A IL 100542A IL 10054291 A IL10054291 A IL 10054291A IL 10054291 A IL10054291 A IL 10054291A IL 100542 A IL100542 A IL 100542A
Authority
IL
Israel
Prior art keywords
pregna
diones
dioxy
alkylidene
ene
Prior art date
Application number
IL10054291A
Other languages
English (en)
Other versions
IL100542A0 (en
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of IL100542A0 publication Critical patent/IL100542A0/xx
Publication of IL100542A publication Critical patent/IL100542A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL10054291A 1991-02-04 1991-12-27 Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones IL100542A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9100342A SE9100342D0 (sv) 1991-02-04 1991-02-04 Novel steroid esters

Publications (2)

Publication Number Publication Date
IL100542A0 IL100542A0 (en) 1992-09-06
IL100542A true IL100542A (en) 1997-02-18

Family

ID=20381807

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10054291A IL100542A (en) 1991-02-04 1991-12-27 Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones

Country Status (38)

Country Link
US (1) US5614514A (bg)
EP (1) EP0572451B1 (bg)
JP (1) JP2947933B2 (bg)
KR (1) KR100205835B1 (bg)
CN (3) CN1039329C (bg)
AP (1) AP365A (bg)
AT (1) ATE164589T1 (bg)
BG (1) BG61816B1 (bg)
CA (1) CA2100453A1 (bg)
CZ (1) CZ282057B6 (bg)
DE (1) DE69224982T2 (bg)
DK (1) DK0572451T3 (bg)
DZ (1) DZ1554A1 (bg)
EE (1) EE03110B1 (bg)
ES (1) ES2114931T3 (bg)
FI (1) FI933451A (bg)
HK (1) HK1004335A1 (bg)
HU (1) HU221168B1 (bg)
IE (1) IE920167A1 (bg)
IL (1) IL100542A (bg)
IS (1) IS1653B (bg)
MA (1) MA22407A1 (bg)
MX (1) MX9200374A (bg)
MY (1) MY111502A (bg)
NO (1) NO304074B1 (bg)
NZ (1) NZ241211A (bg)
PL (1) PL170383B1 (bg)
PT (1) PT100087B (bg)
RO (1) RO111272B1 (bg)
RU (1) RU2112775C1 (bg)
SE (1) SE9100342D0 (bg)
SK (1) SK281802B6 (bg)
TN (1) TNSN92008A1 (bg)
TW (1) TW287166B (bg)
UA (1) UA43825C2 (bg)
WO (1) WO1992013873A1 (bg)
YU (1) YU48893B (bg)
ZA (1) ZA92234B (bg)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9100341D0 (sv) * 1991-02-04 1991-02-04 Astra Ab Novel steroids
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
ES2341532T3 (es) 1999-05-27 2010-06-22 Euro-Celtique S.A. Preparacion con povidona yodada para el tratamiento de heridas.
HRP20010018A2 (en) 2001-01-09 2002-12-31 Pliva D D Novel anti-inflammatory compounds
AU2003217535A1 (en) * 2002-02-20 2003-09-09 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids
US20050009798A1 (en) 2002-02-20 2005-01-13 Sepracor Inc. Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
EP1521764A2 (en) 2002-07-08 2005-04-13 PLIVA-ISTRAZIVACKI INSTITUT d.o.o. New compounds, compositions and methods for treatment of inflammatory diseases and conditions
ES2325495T3 (es) 2002-07-08 2009-09-07 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Moleculas hibridas de macrolidos con moleculas anti-inflamatorias esteroideas y no esteroideas.
US20040157810A1 (en) * 2002-08-23 2004-08-12 Teicher Martin H. Corticosteroid conjugates and uses thereof
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
HRP20030324A2 (en) 2003-04-24 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. Compounds of antiinflammatory effect
HRP20030604A2 (en) 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
WO2005016352A1 (en) * 2003-08-05 2005-02-24 Sepracor Inc. AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ß2 ADRENERGIC AGONISTS
KR20070083811A (ko) 2004-10-27 2007-08-24 글락소스미쓰클라인 이스트라지바치키 센타 자그레브 디.오.오. 항-염증 활성을 가진 접합체
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки
US8737506B1 (en) 2010-12-29 2014-05-27 Sprint Communications Company L.P. Determination of transmit diversity transmission delays
US8437713B1 (en) 2011-02-16 2013-05-07 Sprint Communications Company L.P. Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en) 2011-06-30 2013-10-22 Sprint Communications Company L.P. Power status multipath search window sizing for wireless communications
WO2013119988A1 (en) 2012-02-10 2013-08-15 Taiwan Liposome Company, Ltd Pharmaceutical compositions to reduce complications of ocular steroid
JP5965187B2 (ja) * 2012-03-30 2016-08-03 小林製薬株式会社 油性軟膏剤
CN109985048B (zh) * 2017-12-29 2021-06-29 广州市赛普特医药科技股份有限公司 2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) * 1964-03-24 Chioacyl
US3197469A (en) * 1958-08-06 1965-07-27 Pharmaceutical Res Products In 16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) * 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) * 1965-12-28 1967-12-12 Merck & Co Inc Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) * 1971-12-07 1973-09-11 American Cyanamid Co Method of using steroid acetonides
SE378109B (bg) * 1972-05-19 1975-08-18 Bofors Ab
US3796701A (en) * 1973-02-26 1974-03-12 Squibb & Sons Inc 5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) * 1980-12-05 1981-12-08 The Upjohn Company 9α-Debromination
JPS58176485A (ja) * 1982-04-08 1983-10-15 Nippon Denso Co Ltd 可変容量圧縮機
US4749649A (en) * 1983-05-16 1988-06-07 The Upjohn Company Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) * 1983-09-26 1985-04-17 Ota Seiyaku Kk フルオシノロン１６，１７−アセトニド２１−ブチレ−トおよびその製造法
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Also Published As

Publication number Publication date
DE69224982T2 (de) 1998-07-30
MY111502A (en) 2000-07-31
NO304074B1 (no) 1998-10-19
TNSN92008A1 (fr) 1993-06-08
DK0572451T3 (da) 1998-10-19
ES2114931T3 (es) 1998-06-16
KR100205835B1 (ko) 1999-07-01
BG61816B1 (bg) 1998-06-30
HU9302243D0 (en) 1993-10-28
JP2947933B2 (ja) 1999-09-13
IE920167A1 (en) 1992-08-12
US5614514A (en) 1997-03-25
PT100087A (pt) 1993-05-31
EE03110B1 (et) 1998-08-17
TW287166B (bg) 1996-10-01
NO932762L (no) 1993-08-02
CN1155418A (zh) 1997-07-30
YU6492A (sh) 1994-12-28
JPH06505233A (ja) 1994-06-16
FI933451A0 (fi) 1993-08-03
CZ149593A3 (en) 1994-03-16
PT100087B (pt) 1999-09-30
NZ241211A (en) 1993-08-26
RU2112775C1 (ru) 1998-06-10
WO1992013873A1 (en) 1992-08-20
EP0572451B1 (en) 1998-04-01
EP0572451A1 (en) 1993-12-08
CN1064078A (zh) 1992-09-02
AU661472B2 (en) 1995-07-27
DE69224982D1 (de) 1998-05-07
BG98011A (bg) 1994-04-29
HU221168B1 (en) 2002-08-28
IS1653B (is) 1997-06-20
CA2100453A1 (en) 1992-08-05
AU1235892A (en) 1992-09-07
UA43825C2 (uk) 2002-01-15
FI933451A (fi) 1993-08-03
RO111272B1 (ro) 1996-08-30
HK1004335A1 (en) 1998-11-20
NO932762D0 (no) 1993-08-02
AP365A (en) 1994-10-21
YU48893B (sh) 2002-10-18
MX9200374A (es) 1992-08-01
PL170383B1 (pl) 1996-12-31
CZ282057B6 (cs) 1997-05-14
SE9100342D0 (sv) 1991-02-04
CN1076607C (zh) 2001-12-26
SK281802B6 (sk) 2001-08-06
ATE164589T1 (de) 1998-04-15
ZA92234B (en) 1992-10-28
DZ1554A1 (fr) 2002-02-17
AP9200354A0 (en) 1992-01-31
IL100542A0 (en) 1992-09-06
IS3809A (is) 1992-08-05
CN1158726A (zh) 1997-09-10
CN1076606C (zh) 2001-12-26
SK79793A3 (en) 1994-03-09
MA22407A1 (fr) 1992-10-01
CN1039329C (zh) 1998-07-29
HUT64972A (en) 1994-03-28

Similar Documents

Publication Publication Date Title
IL100542A (en) Esters of 16, 17-alkylidene-dioxy-6-and/or 9-fluoro-11,21-dihydroxy-pregna-4-ene (and-1-4-diene)-3,20-diones
GB2232552B (en) Picture-in-picture circuitry
GB9013592D0 (en) Catheters
EP0420993A4 (en) Catheter
GR900100525A (en) Catheter
GB9314640D0 (en) Tunnellimg catheter
GB9318932D0 (en) Vascular investigation
GB9008782D0 (en) Picture-in-picture circuitry
HUT62375A (en) Small ventilator
GB9314891D0 (en) Refractometer
GB2238245B (en) Catheters
GB8804608D0 (en) Teletext decoder arrangements
ZA914555B (en) 2-methoximinocarboxylic esters
IL99309A0 (en) Acrylate esters of 1,1,1-trishydroxy-phenylethane
GB8913905D0 (en) Teletext decoders
GB2284158B (en) Catheter
GB8913903D0 (en) Teletext decoders
GB9111046D0 (en) Shelving assembly
GB9218762D0 (en) Esters
AU99978S (en) Video shelving
AU105027S (en) Video shelving
GB9200642D0 (en) Tonometer
GB9214888D0 (en) Tonometer
GB9215877D0 (en) Catheter assembly
IL101264A0 (en) Desktop envelope maker

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees