IL100196A - Steroids B2-91- Ethylene-Bridged as Aromatase Inhibitors - Google Patents

Steroids B2-91- Ethylene-Bridged as Aromatase Inhibitors

Info

Publication number
IL100196A
IL100196A IL10019691A IL10019691A IL100196A IL 100196 A IL100196 A IL 100196A IL 10019691 A IL10019691 A IL 10019691A IL 10019691 A IL10019691 A IL 10019691A IL 100196 A IL100196 A IL 100196A
Authority
IL
Israel
Prior art keywords
alkanoyl
compound
ethylene
androst
ene
Prior art date
Application number
IL10019691A
Other languages
English (en)
Hebrew (he)
Other versions
IL100196A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL100196A0 publication Critical patent/IL100196A0/xx
Publication of IL100196A publication Critical patent/IL100196A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
IL10019691A 1990-11-30 1991-11-28 Steroids B2-91- Ethylene-Bridged as Aromatase Inhibitors IL100196A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/621,184 US5166201A (en) 1990-11-30 1990-11-30 2β,19-ethylene bridged steroids as aromatase inhibitors

Publications (2)

Publication Number Publication Date
IL100196A0 IL100196A0 (en) 1992-08-18
IL100196A true IL100196A (en) 1996-03-31

Family

ID=24489093

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10019691A IL100196A (en) 1990-11-30 1991-11-28 Steroids B2-91- Ethylene-Bridged as Aromatase Inhibitors

Country Status (20)

Country Link
US (1) US5166201A (ja)
EP (1) EP0488383B1 (ja)
JP (1) JP3143876B2 (ja)
KR (1) KR100190776B1 (ja)
CN (1) CN1033975C (ja)
AT (1) ATE142639T1 (ja)
AU (1) AU635444B2 (ja)
CA (1) CA2056638C (ja)
DE (1) DE69122048T2 (ja)
DK (1) DK0488383T3 (ja)
ES (1) ES2094183T3 (ja)
FI (1) FI102073B (ja)
GR (1) GR3021981T3 (ja)
HU (1) HU210830B (ja)
IE (1) IE914168A1 (ja)
IL (1) IL100196A (ja)
NO (1) NO180304C (ja)
NZ (1) NZ240738A (ja)
PT (1) PT99661B (ja)
ZA (1) ZA919296B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19510862A1 (de) * 1995-03-16 1996-09-19 Schering Ag Verwendung von Antiestrogenen zur männlichen Fertilitätskontrolle
EP1079859B1 (en) 1998-05-22 2010-07-14 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3627756A (en) * 1970-04-23 1971-12-14 Searle & Co N-dialkylaminoalkyl-n-(2{62 ,19-epoxy-5{60 -androstan-17{62 -yl)amines/formamides and 3{60 -halo derivatives thereof
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
GB8501035D0 (en) * 1985-01-16 1985-02-20 Senior J Prostaglandins
US4882322A (en) * 1988-10-27 1989-11-21 Merrell Dow Pharmaceuticals Inc. 3β,17β-hydroxy-substituted steroids and related steroidal compounds

Also Published As

Publication number Publication date
IL100196A0 (en) 1992-08-18
FI915623A0 (fi) 1991-11-28
EP0488383B1 (en) 1996-09-11
PT99661A (pt) 1992-10-30
US5166201A (en) 1992-11-24
NO914710L (no) 1992-06-01
ES2094183T3 (es) 1997-01-16
HUT59937A (en) 1992-07-28
FI102073B1 (fi) 1998-10-15
ZA919296B (en) 1992-08-26
NO180304C (no) 1997-04-02
CN1033975C (zh) 1997-02-05
GR3021981T3 (en) 1997-03-31
FI102073B (fi) 1998-10-15
DK0488383T3 (da) 1996-09-30
IE914168A1 (en) 1992-06-03
HU210830B (en) 1995-08-28
NO180304B (no) 1996-12-16
NO914710D0 (no) 1991-11-29
EP0488383A1 (en) 1992-06-03
KR100190776B1 (ko) 1999-06-01
PT99661B (pt) 1999-05-31
NZ240738A (en) 1993-11-25
AU8812891A (en) 1992-06-04
CN1061974A (zh) 1992-06-17
FI915623A (fi) 1992-05-31
DE69122048D1 (de) 1996-10-17
JP3143876B2 (ja) 2001-03-07
ATE142639T1 (de) 1996-09-15
DE69122048T2 (de) 1997-02-20
CA2056638A1 (en) 1992-05-31
KR920009842A (ko) 1992-06-25
AU635444B2 (en) 1993-03-18
JPH04290898A (ja) 1992-10-15
CA2056638C (en) 2002-03-05
HU913739D0 (en) 1992-02-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees