GR3021981T3 - 2-beta,19-ethylene bridged steroids as aromatase inhibitors - Google Patents

2-beta,19-ethylene bridged steroids as aromatase inhibitors

Info

Publication number
GR3021981T3
GR3021981T3 GR960403414T GR960403414T GR3021981T3 GR 3021981 T3 GR3021981 T3 GR 3021981T3 GR 960403414 T GR960403414 T GR 960403414T GR 960403414 T GR960403414 T GR 960403414T GR 3021981 T3 GR3021981 T3 GR 3021981T3
Authority
GR
Greece
Prior art keywords
aromatase inhibitors
beta
ethylene bridged
bridged steroids
steroids
Prior art date
Application number
GR960403414T
Other languages
English (en)
Inventor
J O'neal Johnston
Norton P Peet
Joseph P Burkhart
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of GR3021981T3 publication Critical patent/GR3021981T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
GR960403414T 1990-11-30 1996-12-11 2-beta,19-ethylene bridged steroids as aromatase inhibitors GR3021981T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/621,184 US5166201A (en) 1990-11-30 1990-11-30 2β,19-ethylene bridged steroids as aromatase inhibitors

Publications (1)

Publication Number Publication Date
GR3021981T3 true GR3021981T3 (en) 1997-03-31

Family

ID=24489093

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960403414T GR3021981T3 (en) 1990-11-30 1996-12-11 2-beta,19-ethylene bridged steroids as aromatase inhibitors

Country Status (20)

Country Link
US (1) US5166201A (el)
EP (1) EP0488383B1 (el)
JP (1) JP3143876B2 (el)
KR (1) KR100190776B1 (el)
CN (1) CN1033975C (el)
AT (1) ATE142639T1 (el)
AU (1) AU635444B2 (el)
CA (1) CA2056638C (el)
DE (1) DE69122048T2 (el)
DK (1) DK0488383T3 (el)
ES (1) ES2094183T3 (el)
FI (1) FI102073B1 (el)
GR (1) GR3021981T3 (el)
HU (1) HU210830B (el)
IE (1) IE914168A1 (el)
IL (1) IL100196A (el)
NO (1) NO180304C (el)
NZ (1) NZ240738A (el)
PT (1) PT99661B (el)
ZA (1) ZA919296B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19510862A1 (de) * 1995-03-16 1996-09-19 Schering Ag Verwendung von Antiestrogenen zur männlichen Fertilitätskontrolle
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
CA2969926C (en) 2009-02-20 2018-05-15 2-Bbb Medicines B.V. Glutathione-based drug delivery system
EP4218718A3 (en) 2009-05-06 2024-04-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3627756A (en) * 1970-04-23 1971-12-14 Searle & Co N-dialkylaminoalkyl-n-(2{62 ,19-epoxy-5{60 -androstan-17{62 -yl)amines/formamides and 3{60 -halo derivatives thereof
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
GB8501035D0 (en) * 1985-01-16 1985-02-20 Senior J Prostaglandins
US4882322A (en) * 1988-10-27 1989-11-21 Merrell Dow Pharmaceuticals Inc. 3β,17β-hydroxy-substituted steroids and related steroidal compounds

Also Published As

Publication number Publication date
CA2056638C (en) 2002-03-05
KR920009842A (ko) 1992-06-25
JP3143876B2 (ja) 2001-03-07
US5166201A (en) 1992-11-24
DE69122048T2 (de) 1997-02-20
AU8812891A (en) 1992-06-04
AU635444B2 (en) 1993-03-18
EP0488383B1 (en) 1996-09-11
HU913739D0 (en) 1992-02-28
ZA919296B (en) 1992-08-26
IL100196A0 (en) 1992-08-18
NZ240738A (en) 1993-11-25
NO914710L (no) 1992-06-01
DE69122048D1 (de) 1996-10-17
EP0488383A1 (en) 1992-06-03
HUT59937A (en) 1992-07-28
CN1061974A (zh) 1992-06-17
NO914710D0 (no) 1991-11-29
NO180304C (no) 1997-04-02
FI915623A (fi) 1992-05-31
JPH04290898A (ja) 1992-10-15
IL100196A (en) 1996-03-31
HU210830B (en) 1995-08-28
PT99661B (pt) 1999-05-31
KR100190776B1 (ko) 1999-06-01
FI102073B (fi) 1998-10-15
IE914168A1 (en) 1992-06-03
NO180304B (no) 1996-12-16
ATE142639T1 (de) 1996-09-15
FI102073B1 (fi) 1998-10-15
PT99661A (pt) 1992-10-30
FI915623A0 (fi) 1991-11-28
DK0488383T3 (da) 1996-09-30
ES2094183T3 (es) 1997-01-16
CA2056638A1 (en) 1992-05-31
CN1033975C (zh) 1997-02-05

Similar Documents

Publication Publication Date Title
EP1042352A4 (en) ANDROGENIC STEROID COMPOUNDS AND METHOD OF MANUFACTURE AND USE THEREOF
AP9801312A0 (en) 4-aminopyrrole (3,2-d) pyrimidines as neuropeptide y receptor anatagonist.
EP0893446A4 (el)
GR3021981T3 (en) 2-beta,19-ethylene bridged steroids as aromatase inhibitors
WO1995018821A3 (en) Novel antiandrogenic agents and related pharmaceutical compositions and methods of use
AU1345699A (en) Steroid 3-o-sulphamate derivatives as inhibitors of oestrone sulphatase
TW198053B (el)
BG103050A (en) New derivatives of erythromycin, method for their preparation and application as medicamentous forms
DK0559706T3 (da) 2 beta,19-methylenamino-broforbundne steroider som aromataseinhibitorer.
TW334337B (en) Preparation and composition for a compound of controlling and preventing phytopathogenic fungi
CA2032311A1 (en) 2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase and 19-hydroxylase inhibitors
AU7378491A (en) Haloethyl-substituted steroidal enzyme inhibitors
EP0175570A3 (en) Process for the preparation of aromatic-1,4-oxazepinones and thiones
ES8604512A1 (es) Procedimiento para la obtencion de fenilhidrazonpirrolidinas substituidas
JPS52131580A (en) N-substituted pyridinium-2-sulfonylimines, containing same as active ingredient