IE920442A1 - 5-heteroyl indole derivatives - Google Patents

5-heteroyl indole derivatives

Info

Publication number
IE920442A1
IE920442A1 IE044292A IE920442A IE920442A1 IE 920442 A1 IE920442 A1 IE 920442A1 IE 044292 A IE044292 A IE 044292A IE 920442 A IE920442 A IE 920442A IE 920442 A1 IE920442 A1 IE 920442A1
Authority
IE
Ireland
Prior art keywords
compound
mmol
indol
alkyl
hydrogen
Prior art date
Application number
IE044292A
Other languages
English (en)
Inventor
Jolanta Teresa Nowakowski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE920442A1 publication Critical patent/IE920442A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Luminescent Compositions (AREA)
IE044292A 1991-02-12 1992-02-11 5-heteroyl indole derivatives IE920442A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65471291A 1991-02-12 1991-02-12

Publications (1)

Publication Number Publication Date
IE920442A1 true IE920442A1 (en) 1992-08-12

Family

ID=24625959

Family Applications (1)

Application Number Title Priority Date Filing Date
IE044292A IE920442A1 (en) 1991-02-12 1992-02-11 5-heteroyl indole derivatives

Country Status (24)

Country Link
EP (1) EP0571471B1 (cg-RX-API-DMAC10.html)
JP (1) JPH07121942B2 (cg-RX-API-DMAC10.html)
KR (1) KR930703305A (cg-RX-API-DMAC10.html)
AT (1) ATE135005T1 (cg-RX-API-DMAC10.html)
AU (1) AU655456B2 (cg-RX-API-DMAC10.html)
CA (1) CA2101521A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ165693A3 (cg-RX-API-DMAC10.html)
DE (1) DE69208868T2 (cg-RX-API-DMAC10.html)
DK (1) DK0571471T3 (cg-RX-API-DMAC10.html)
ES (1) ES2084347T3 (cg-RX-API-DMAC10.html)
FI (1) FI933551A0 (cg-RX-API-DMAC10.html)
GR (1) GR3019778T3 (cg-RX-API-DMAC10.html)
HU (1) HUT65766A (cg-RX-API-DMAC10.html)
IE (1) IE920442A1 (cg-RX-API-DMAC10.html)
IL (1) IL100888A0 (cg-RX-API-DMAC10.html)
MX (1) MX9200569A (cg-RX-API-DMAC10.html)
MY (1) MY131298A (cg-RX-API-DMAC10.html)
NO (1) NO932859D0 (cg-RX-API-DMAC10.html)
NZ (1) NZ241584A (cg-RX-API-DMAC10.html)
PT (1) PT100114A (cg-RX-API-DMAC10.html)
TW (1) TW263508B (cg-RX-API-DMAC10.html)
WO (1) WO1992013856A1 (cg-RX-API-DMAC10.html)
YU (1) YU13792A (cg-RX-API-DMAC10.html)
ZA (1) ZA92969B (cg-RX-API-DMAC10.html)

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TW288010B (cg-RX-API-DMAC10.html) * 1992-03-05 1996-10-11 Pfizer
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US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
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GB9501865D0 (en) * 1995-01-31 1995-03-22 Merck Sharp & Dohme Therapeutic agents
KR19980703048A (ko) * 1995-03-20 1998-09-05 피터쥐.스트링거 5-치환-3-(1,2,3,6-테트라히드로피리딘-4-일)- 및 3-(피페리딘-4-일)-1ｈ-인돌: 신규한 5-ｈｔ1ｆ 아고니스트
US5942536A (en) * 1995-10-10 1999-08-24 Eli Lilly And Company N- 2-substituted-3-(2-aminoethyl)-1H-indol-5-YL!-Amides: new 5-HT1F agonists
GB9523583D0 (en) * 1995-11-17 1996-01-17 Merck Sharp & Dohme Therapeutic agents
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
FR2763243A1 (fr) * 1997-05-14 1998-11-20 Pf Medicament Utilisation d'amines indoliques comme medicaments antithrombotiques
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
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JP4597386B2 (ja) * 1999-04-21 2010-12-15 エヌピーエス ファーマシューティカルス，インコーポレーテッド ５−ｈｔ６親和性を有するピペリジン−インドール化合物
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IL154685A0 (en) * 2000-10-20 2003-09-17 Biovitrum Ab 2-,3-,4-, or 5-substituted-n1-(benzensulfonyl) indoles and their use in therapy
DE10121217A1 (de) 2001-04-30 2002-10-31 Merck Patent Gmbh 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden
WO2003099206A2 (en) 2002-05-21 2003-12-04 Bristol-Myers Squibb Company Indole compounds useful as impdh inhibitors
PT1581492E (pt) 2002-11-28 2008-09-19 Suven Life Sciences Ltd Indoles n-arilsulfonil-3-substituídos possuindo afinidade de receptor de serotonina, processo para a sua preparação e composição farmacêutica contendo os mesmos
US7332508B2 (en) * 2002-12-18 2008-02-19 Novo Nordisk A/S Substituted homopiperidine, piperidine or pyrrolidine derivatives
WO2005005439A1 (en) * 2003-07-09 2005-01-20 Suven Life Sciences Limited Benzothiazino indoles
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WO2007016979A2 (en) * 2005-07-29 2007-02-15 4Sc Ag NOVEL HETEROCYCLIC NF-κB INHIBITORS
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EP2049481A2 (en) * 2006-08-09 2009-04-22 SmithKline Beecham Corporation Novel compounds as antagonists or inverse agonists for opioid receptors
TW200848021A (en) 2007-03-06 2008-12-16 Wyeth Corp Sulfonylated heterocycles useful for modulation of the progesterone receptor
CA2705835A1 (en) 2007-11-16 2009-05-22 Neuraxon, Inc. Indole compounds and methods for treating visceral pain
JP6063870B2 (ja) * 2010-11-08 2017-01-18 ライセラ・コーポレイション ＲＯＲγ活性の阻害用のＮ−スルホニル化テトラヒドロキノリンおよび関連二環化合物および病気の治療
RU2014149136A (ru) 2012-05-08 2016-07-10 Мерк Шарп И Доум Корп. ТЕТРАГИДРОНАФТИРИДИНОВЫЕ И РОДСТВЕННЫЕ БИЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ ДЛЯ ИНГИБИРОВАНИЯ RORγ АКТИВНОСТИ И ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ
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Also Published As

Publication number Publication date
YU13792A (sh) 1994-11-15
HU9302328D0 (en) 1993-10-28
DE69208868T2 (de) 1996-10-17
DK0571471T3 (da) 1996-04-01
FI933551A7 (fi) 1993-08-11
MY131298A (en) 2007-08-30
NO932859L (no) 1993-08-11
FI933551L (fi) 1993-08-11
IL100888A0 (en) 1992-11-15
FI933551A0 (fi) 1993-08-11
NO932859D0 (no) 1993-08-11
ZA92969B (en) 1993-08-11
CA2101521A1 (en) 1992-08-13
GR3019778T3 (en) 1996-07-31
EP0571471B1 (en) 1996-03-06
DE69208868D1 (de) 1996-04-11
ATE135005T1 (de) 1996-03-15
EP0571471A1 (en) 1993-12-01
MX9200569A (es) 1992-08-01
ES2084347T3 (es) 1996-05-01
HUT65766A (en) 1994-07-28
TW263508B (cg-RX-API-DMAC10.html) 1995-11-21
NZ241584A (en) 1994-12-22
KR930703305A (ko) 1993-11-29
WO1992013856A1 (en) 1992-08-20
JPH06500122A (ja) 1994-01-06
CZ165693A3 (en) 1994-05-18
AU655456B2 (en) 1994-12-22
PT100114A (pt) 1993-05-31
AU1263792A (en) 1992-09-07
JPH07121942B2 (ja) 1995-12-25

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