IE58786B1 - A selective acylation process - Google Patents
A selective acylation processInfo
- Publication number
- IE58786B1 IE58786B1 IE243284A IE243284A IE58786B1 IE 58786 B1 IE58786 B1 IE 58786B1 IE 243284 A IE243284 A IE 243284A IE 243284 A IE243284 A IE 243284A IE 58786 B1 IE58786 B1 IE 58786B1
- Authority
- IE
- Ireland
- Prior art keywords
- bis
- chloroethyl
- chloride
- estradiol
- process according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyridine Compounds (AREA)
- Machines For Manufacturing Corrugated Board In Mechanical Paper-Making Processes (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Press Drives And Press Lines (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8305596A SE8305596D0 (sv) | 1983-10-12 | 1983-10-12 | A selective acylation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE842432L IE842432L (en) | 1985-04-12 |
| IE58786B1 true IE58786B1 (en) | 1993-11-17 |
Family
ID=20352856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE243284A IE58786B1 (en) | 1983-10-12 | 1984-09-24 | A selective acylation process |
Country Status (11)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2520074B2 (ja) * | 1992-06-11 | 1996-07-31 | 呉羽化学工業株式会社 | 新規なエストラジオ―ル誘導体−クロラムブチル結合体、その製造方法、及び医薬製剤 |
| JP2554005B2 (ja) * | 1993-02-18 | 1996-11-13 | 株式会社パーマケム・アジア | エストラムスチンフォスフェート又はその塩類の精製方法 |
| JP2554006B2 (ja) * | 1993-03-12 | 1996-11-13 | 株式会社パーマケム・アジア | エストラジオールの選択的アシル化方法 |
| DE19906159A1 (de) * | 1999-02-09 | 2000-08-10 | Schering Ag | 16-Hydroxyestratriene als selektiv wirksame Estrogene |
| US9440899B2 (en) | 2014-12-15 | 2016-09-13 | Rohm And Haas Electronic Materials Llc | Purification method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1016959A (en) * | 1963-04-09 | 1966-01-12 | Leo Ab | Substituted steroid hormones |
| DE1958954C3 (de) * | 1969-11-24 | 1978-11-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Veresterung von Alkoholen |
| GB1528321A (en) * | 1975-07-07 | 1978-10-11 | Leo Ab | Acylation process for the preparation of phenolic n,n-di-substituted carbamate esters |
| GB1565680A (en) * | 1976-12-31 | 1980-04-23 | Leo Ab | Method for the preparation of carboxylic acid esters |
-
1983
- 1983-10-12 SE SE8305596A patent/SE8305596D0/xx unknown
-
1984
- 1984-09-24 IE IE243284A patent/IE58786B1/en not_active IP Right Cessation
- 1984-09-26 IL IL73110A patent/IL73110A/xx not_active IP Right Cessation
- 1984-09-28 US US06/655,950 patent/US4592869A/en not_active Expired - Lifetime
- 1984-10-03 DE DE8484111804T patent/DE3475308D1/de not_active Expired
- 1984-10-03 AT AT84111804T patent/ATE38840T1/de not_active IP Right Cessation
- 1984-10-03 EP EP84111804A patent/EP0138153B1/en not_active Expired
- 1984-10-09 CA CA000464993A patent/CA1244822A/en not_active Expired
- 1984-10-09 FI FI843964A patent/FI81105C/fi not_active IP Right Cessation
- 1984-10-11 HU HU843817A patent/HU195231B/hu unknown
- 1984-10-12 JP JP59214025A patent/JPS6097996A/ja active Granted
-
1993
- 1993-03-22 JP JP5062067A patent/JPH0720938B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0720938B2 (ja) | 1995-03-08 |
| FI81105C (fi) | 1990-09-10 |
| EP0138153B1 (en) | 1988-11-23 |
| US4592869A (en) | 1986-06-03 |
| FI843964L (fi) | 1985-04-13 |
| FI81105B (fi) | 1990-05-31 |
| SE8305596D0 (sv) | 1983-10-12 |
| EP0138153A2 (en) | 1985-04-24 |
| EP0138153A3 (en) | 1986-04-09 |
| JPH0559920B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-09-01 |
| ATE38840T1 (de) | 1988-12-15 |
| IL73110A (en) | 1988-02-29 |
| HUT37157A (en) | 1985-11-28 |
| DE3475308D1 (en) | 1988-12-29 |
| FI843964A0 (fi) | 1984-10-09 |
| JPS6097996A (ja) | 1985-05-31 |
| IE842432L (en) | 1985-04-12 |
| JPH0680690A (ja) | 1994-03-22 |
| CA1244822A (en) | 1988-11-15 |
| HU195231B (en) | 1988-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |