IE46505B1 - Pyrido (2,1-b) quinazoline derivatives - Google Patents

Pyrido (2,1-b) quinazoline derivatives

Info

Publication number
IE46505B1
IE46505B1 IE582/78A IE58278A IE46505B1 IE 46505 B1 IE46505 B1 IE 46505B1 IE 582/78 A IE582/78 A IE 582/78A IE 58278 A IE58278 A IE 58278A IE 46505 B1 IE46505 B1 IE 46505B1
Authority
IE
Ireland
Prior art keywords
formula
group
compound
pyrido
alkyl
Prior art date
Application number
IE582/78A
Other languages
English (en)
Other versions
IE780582L (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE780582L publication Critical patent/IE780582L/xx
Publication of IE46505B1 publication Critical patent/IE46505B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IE582/78A 1977-03-24 1978-03-23 Pyrido (2,1-b) quinazoline derivatives IE46505B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78093977A 1977-03-24 1977-03-24
US87156478A 1978-01-23 1978-01-23

Publications (2)

Publication Number Publication Date
IE780582L IE780582L (en) 1978-09-24
IE46505B1 true IE46505B1 (en) 1983-06-29

Family

ID=27119777

Family Applications (1)

Application Number Title Priority Date Filing Date
IE582/78A IE46505B1 (en) 1977-03-24 1978-03-23 Pyrido (2,1-b) quinazoline derivatives

Country Status (23)

Country Link
JP (2) JPS53119897A (fr)
AR (3) AR218060A1 (fr)
AT (2) AT367051B (fr)
AU (2) AU521352B2 (fr)
DE (2) DE2812586A1 (fr)
DK (2) DK128878A (fr)
ES (13) ES468126A1 (fr)
FI (2) FI780918A (fr)
FR (2) FR2384771A1 (fr)
GB (2) GB1601991A (fr)
GR (2) GR73170B (fr)
HU (1) HU180782B (fr)
IE (1) IE46505B1 (fr)
IL (2) IL54326A (fr)
IT (2) IT1093710B (fr)
LU (2) LU79293A1 (fr)
MC (2) MC1185A1 (fr)
NL (2) NL7803112A (fr)
NO (2) NO781051L (fr)
NZ (2) NZ186759A (fr)
PH (2) PH14130A (fr)
PT (2) PT67820A (fr)
SE (2) SE7803418L (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425A1 (de) 1975-12-19 1977-06-30 Boehringer Sohn Ingelheim Chinazolonderivate
DE2845766A1 (de) * 1978-10-18 1980-04-30 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES511866A0 (es) * 1982-04-30 1983-06-01 Lafarquim "procedimiento de obtencion de 2-isopropil pirido (2-1-b) quinazolinas y sus sales no toxicas con actividad antianafilactica".
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (de) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim Neue heterocyclische verbindungen, ihre herstellung und verwendung
JPS62238264A (ja) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk ２−ハロ−５−アセチルピリジン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
IT1093710B (it) 1985-07-26
IL54326A0 (en) 1978-06-15
SE7803418L (sv) 1978-09-25
IL54328A0 (en) 1978-06-15
IE780582L (en) 1978-09-24
PT67821B (en) 1980-03-04
NZ186760A (en) 1981-03-16
DE2812586A1 (de) 1978-09-28
FI780917A (fi) 1978-09-25
AR218480A1 (es) 1980-06-13
ES478331A1 (es) 1979-11-16
ES478328A1 (es) 1979-11-01
ES478326A1 (es) 1979-11-01
AU521352B2 (en) 1982-04-01
ES478330A1 (es) 1979-11-01
GR72948B (fr) 1984-01-17
ES478329A1 (es) 1979-11-01
AR218060A1 (es) 1980-05-15
DE2812585A1 (de) 1978-09-28
ATA210478A (de) 1981-10-15
PT67820A (en) 1978-04-01
NL7803122A (nl) 1978-09-26
DK128878A (da) 1978-09-25
ES468127A1 (es) 1979-09-16
FI780918A (fi) 1978-09-25
AU3447578A (en) 1979-09-27
GB1601991A (en) 1981-11-04
LU79293A1 (de) 1979-05-25
DK132778A (da) 1978-09-25
ES478332A1 (es) 1979-11-16
IT7821655A0 (it) 1978-03-24
LU79290A1 (de) 1979-05-25
NZ186759A (en) 1981-03-16
FR2384770A1 (fr) 1978-10-20
IL54328A (en) 1982-03-31
FR2384770B1 (fr) 1980-10-24
AR225415A1 (es) 1982-03-31
PH14130A (en) 1981-02-26
IT7821578A0 (it) 1978-03-23
AT367050B (de) 1982-05-25
ES478333A1 (es) 1979-11-16
HU180782B (en) 1983-04-29
ES478324A1 (es) 1979-11-01
GR73170B (fr) 1983-02-14
AU3447478A (en) 1979-09-27
PH13915A (en) 1980-11-04
PT67821A (en) 1978-04-01
ATA210278A (de) 1981-10-15
NO781053L (no) 1978-09-26
FR2384771B1 (fr) 1980-04-04
NO781051L (no) 1978-09-26
GB1601371A (en) 1981-10-28
ES478323A1 (es) 1979-11-01
JPS53119897A (en) 1978-10-19
ES468126A1 (es) 1979-09-01
ES478325A1 (es) 1979-11-01
AU521096B2 (en) 1982-03-18
FR2384771A1 (fr) 1978-10-20
MC1186A1 (fr) 1978-12-22
NL7803112A (nl) 1978-09-26
AT367051B (de) 1982-05-25
SE7803419L (sv) 1978-09-25
ES478327A1 (es) 1979-11-01
IT1095493B (it) 1985-08-10
MC1185A1 (fr) 1978-12-22
IL54326A (en) 1982-04-30
JPS53119896A (en) 1978-10-19

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