AU521096B2 - Pyrido [2, 1-b] quinazoline derivatives - Google Patents

Pyrido [2, 1-b] quinazoline derivatives

Info

Publication number
AU521096B2
AU521096B2 AU34475/78A AU3447578A AU521096B2 AU 521096 B2 AU521096 B2 AU 521096B2 AU 34475/78 A AU34475/78 A AU 34475/78A AU 3447578 A AU3447578 A AU 3447578A AU 521096 B2 AU521096 B2 AU 521096B2
Authority
AU
Australia
Prior art keywords
pyrido
quinazoline derivatives
quinazoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU34475/78A
Other versions
AU3447578A (en
Inventor
Wightman Kierstead And Jefferson Wright Tilley Richard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU3447578A publication Critical patent/AU3447578A/en
Application granted granted Critical
Publication of AU521096B2 publication Critical patent/AU521096B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
AU34475/78A 1977-03-24 1978-03-23 Pyrido [2, 1-b] quinazoline derivatives Expired AU521096B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78093977A 1977-03-24 1977-03-24
USUS780939 1977-03-24
US87156478A 1978-01-23 1978-01-23
USUS871564 1978-01-23

Publications (2)

Publication Number Publication Date
AU3447578A AU3447578A (en) 1979-09-27
AU521096B2 true AU521096B2 (en) 1982-03-18

Family

ID=27119777

Family Applications (2)

Application Number Title Priority Date Filing Date
AU34474/78A Expired AU521352B2 (en) 1977-03-24 1978-03-23 Pyrido[2,1-b]quinzoline derivaties
AU34475/78A Expired AU521096B2 (en) 1977-03-24 1978-03-23 Pyrido [2, 1-b] quinazoline derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU34474/78A Expired AU521352B2 (en) 1977-03-24 1978-03-23 Pyrido[2,1-b]quinzoline derivaties

Country Status (23)

Country Link
JP (2) JPS53119897A (en)
AR (3) AR218480A1 (en)
AT (2) AT367051B (en)
AU (2) AU521352B2 (en)
DE (2) DE2812586A1 (en)
DK (2) DK132778A (en)
ES (13) ES468127A1 (en)
FI (2) FI780917A (en)
FR (2) FR2384770A1 (en)
GB (2) GB1601371A (en)
GR (2) GR72948B (en)
HU (1) HU180782B (en)
IE (1) IE46505B1 (en)
IL (2) IL54328A (en)
IT (2) IT1093710B (en)
LU (2) LU79293A1 (en)
MC (2) MC1186A1 (en)
NL (2) NL7803122A (en)
NO (2) NO781053L (en)
NZ (2) NZ186759A (en)
PH (2) PH14130A (en)
PT (2) PT67821B (en)
SE (2) SE7803419L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425A1 (en) 1975-12-19 1977-06-30 Boehringer Sohn Ingelheim CHINAZOLONE DERIVATIVES
DE2845766A1 (en) * 1978-10-18 1980-04-30 Schering Ag PYRIDO ANGLE CLAMP ON 2,1-B ANGLE CLAMP ON -CHINAZOLINONE DERIVATIVES, THEIR PRODUCTION AND USE
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8306729A1 (en) * 1982-04-30 1983-06-01 Lafarquim Novel 2-isopropyl-pyrido[2,1-b]quinazolines and their non-toxic salts, process for their preparation and pharmaceutical compositions containing these compounds
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (en) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim NEW HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE
JPS62238264A (en) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk 2-halo-5-acetylpyridine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
MC1186A1 (en) 1978-12-22
IL54328A0 (en) 1978-06-15
NO781053L (en) 1978-09-26
ES478332A1 (en) 1979-11-16
IT7821655A0 (en) 1978-03-24
AU3447578A (en) 1979-09-27
ES478330A1 (en) 1979-11-01
PH14130A (en) 1981-02-26
IT7821578A0 (en) 1978-03-23
FR2384770A1 (en) 1978-10-20
PH13915A (en) 1980-11-04
NL7803112A (en) 1978-09-26
ES478325A1 (en) 1979-11-01
AU3447478A (en) 1979-09-27
FI780917A (en) 1978-09-25
ES478326A1 (en) 1979-11-01
IE780582L (en) 1978-09-24
HU180782B (en) 1983-04-29
LU79290A1 (en) 1979-05-25
ES478333A1 (en) 1979-11-16
AR218060A1 (en) 1980-05-15
AT367050B (en) 1982-05-25
ES478327A1 (en) 1979-11-01
NZ186760A (en) 1981-03-16
NO781051L (en) 1978-09-26
IT1093710B (en) 1985-07-26
ES468126A1 (en) 1979-09-01
FI780918A (en) 1978-09-25
AT367051B (en) 1982-05-25
ES478328A1 (en) 1979-11-01
ES478323A1 (en) 1979-11-01
GR72948B (en) 1984-01-17
FR2384771B1 (en) 1980-04-04
ATA210478A (en) 1981-10-15
ES478324A1 (en) 1979-11-01
GR73170B (en) 1983-02-14
LU79293A1 (en) 1979-05-25
IE46505B1 (en) 1983-06-29
NL7803122A (en) 1978-09-26
DK128878A (en) 1978-09-25
GB1601991A (en) 1981-11-04
AR225415A1 (en) 1982-03-31
FR2384771A1 (en) 1978-10-20
MC1185A1 (en) 1978-12-22
AU521352B2 (en) 1982-04-01
SE7803418L (en) 1978-09-25
ATA210278A (en) 1981-10-15
GB1601371A (en) 1981-10-28
PT67821A (en) 1978-04-01
IT1095493B (en) 1985-08-10
JPS53119897A (en) 1978-10-19
SE7803419L (en) 1978-09-25
DK132778A (en) 1978-09-25
ES478329A1 (en) 1979-11-01
FR2384770B1 (en) 1980-10-24
IL54326A0 (en) 1978-06-15
IL54326A (en) 1982-04-30
ES468127A1 (en) 1979-09-16
ES478331A1 (en) 1979-11-16
DE2812586A1 (en) 1978-09-28
AR218480A1 (en) 1980-06-13
DE2812585A1 (en) 1978-09-28
PT67821B (en) 1980-03-04
NZ186759A (en) 1981-03-16
JPS53119896A (en) 1978-10-19
IL54328A (en) 1982-03-31
PT67820A (en) 1978-04-01

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