AT367051B - METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS - Google Patents

METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS

Info

Publication number
AT367051B
AT367051B AT0210478A AT210478A AT367051B AT 367051 B AT367051 B AT 367051B AT 0210478 A AT0210478 A AT 0210478A AT 210478 A AT210478 A AT 210478A AT 367051 B AT367051 B AT 367051B
Authority
AT
Austria
Prior art keywords
salts
producing new
new pyrido
chinazoline derivatives
chinazoline
Prior art date
Application number
AT0210478A
Other languages
German (de)
Other versions
ATA210478A (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA210478A publication Critical patent/ATA210478A/en
Priority to AT489981A priority Critical patent/ATA489981A/en
Priority to AT489781A priority patent/ATA489781A/en
Priority to AT489681A priority patent/ATA489681A/en
Priority to AT489881A priority patent/ATA489881A/en
Application granted granted Critical
Publication of AT367051B publication Critical patent/AT367051B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT0210478A 1977-03-24 1978-03-23 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS AT367051B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AT489981A ATA489981A (en) 1977-03-24 1981-11-13 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS
AT489781A ATA489781A (en) 1977-03-24 1981-11-13 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS
AT489681A ATA489681A (en) 1977-03-24 1981-11-13 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS
AT489881A ATA489881A (en) 1977-03-24 1981-11-13 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78093977A 1977-03-24 1977-03-24
US87156478A 1978-01-23 1978-01-23

Publications (2)

Publication Number Publication Date
ATA210478A ATA210478A (en) 1981-10-15
AT367051B true AT367051B (en) 1982-05-25

Family

ID=27119777

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0210278A AT367050B (en) 1977-03-24 1978-03-23 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS
AT0210478A AT367051B (en) 1977-03-24 1978-03-23 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0210278A AT367050B (en) 1977-03-24 1978-03-23 METHOD FOR PRODUCING NEW PYRIDO (2,1-B) CHINAZOLINE DERIVATIVES AND THEIR SALTS

Country Status (23)

Country Link
JP (2) JPS53119897A (en)
AR (3) AR218480A1 (en)
AT (2) AT367050B (en)
AU (2) AU521352B2 (en)
DE (2) DE2812585A1 (en)
DK (2) DK128878A (en)
ES (13) ES468127A1 (en)
FI (2) FI780918A (en)
FR (2) FR2384770A1 (en)
GB (2) GB1601991A (en)
GR (2) GR73170B (en)
HU (1) HU180782B (en)
IE (1) IE46505B1 (en)
IL (2) IL54328A (en)
IT (2) IT1093710B (en)
LU (2) LU79290A1 (en)
MC (2) MC1185A1 (en)
NL (2) NL7803112A (en)
NO (2) NO781053L (en)
NZ (2) NZ186760A (en)
PH (2) PH13915A (en)
PT (2) PT67820A (en)
SE (2) SE7803419L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425C2 (en) * 1975-12-19 1987-03-19 C.H. Boehringer Sohn, 6507 Ingelheim 11-Oxo-11-H-pyrido[2,1-b]-quinazoline-2-carboxylic acid and its salts, processes for their preparation and medicaments
DE2845766A1 (en) * 1978-10-18 1980-04-30 Schering Ag PYRIDO ANGLE CLAMP ON 2,1-B ANGLE CLAMP ON -CHINAZOLINONE DERIVATIVES, THEIR PRODUCTION AND USE
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES8306729A1 (en) * 1982-04-30 1983-06-01 Lafarquim Novel 2-isopropyl-pyrido[2,1-b]quinazolines and their non-toxic salts, process for their preparation and pharmaceutical compositions containing these compounds
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (en) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim NEW HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE
JPS62238264A (en) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk 2-halo-5-acetylpyridine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
IL54328A0 (en) 1978-06-15
ES478332A1 (en) 1979-11-16
IT7821655A0 (en) 1978-03-24
NZ186760A (en) 1981-03-16
ES478329A1 (en) 1979-11-01
GB1601371A (en) 1981-10-28
FR2384771B1 (en) 1980-04-04
NO781051L (en) 1978-09-26
AR218480A1 (en) 1980-06-13
ES478324A1 (en) 1979-11-01
GR73170B (en) 1983-02-14
FI780918A (en) 1978-09-25
MC1186A1 (en) 1978-12-22
ES478331A1 (en) 1979-11-16
IT1093710B (en) 1985-07-26
ES478328A1 (en) 1979-11-01
ES478326A1 (en) 1979-11-01
ES478325A1 (en) 1979-11-01
ATA210478A (en) 1981-10-15
ES478333A1 (en) 1979-11-16
PT67820A (en) 1978-04-01
NZ186759A (en) 1981-03-16
PH13915A (en) 1980-11-04
GB1601991A (en) 1981-11-04
NL7803112A (en) 1978-09-26
IT1095493B (en) 1985-08-10
SE7803419L (en) 1978-09-25
LU79293A1 (en) 1979-05-25
FI780917A (en) 1978-09-25
AR218060A1 (en) 1980-05-15
DK128878A (en) 1978-09-25
ES468127A1 (en) 1979-09-16
ES478330A1 (en) 1979-11-01
AU3447578A (en) 1979-09-27
IL54328A (en) 1982-03-31
JPS53119896A (en) 1978-10-19
FR2384770A1 (en) 1978-10-20
ES478323A1 (en) 1979-11-01
IE46505B1 (en) 1983-06-29
PH14130A (en) 1981-02-26
DE2812586A1 (en) 1978-09-28
ES468126A1 (en) 1979-09-01
NO781053L (en) 1978-09-26
NL7803122A (en) 1978-09-26
PT67821A (en) 1978-04-01
MC1185A1 (en) 1978-12-22
IL54326A (en) 1982-04-30
SE7803418L (en) 1978-09-25
FR2384770B1 (en) 1980-10-24
DK132778A (en) 1978-09-25
LU79290A1 (en) 1979-05-25
IT7821578A0 (en) 1978-03-23
AU3447478A (en) 1979-09-27
AU521096B2 (en) 1982-03-18
AU521352B2 (en) 1982-04-01
IL54326A0 (en) 1978-06-15
AT367050B (en) 1982-05-25
PT67821B (en) 1980-03-04
AR225415A1 (en) 1982-03-31
ATA210278A (en) 1981-10-15
FR2384771A1 (en) 1978-10-20
IE780582L (en) 1978-09-24
DE2812585A1 (en) 1978-09-28
GR72948B (en) 1984-01-17
ES478327A1 (en) 1979-11-01
HU180782B (en) 1983-04-29
JPS53119897A (en) 1978-10-19

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties