FR2384771B1 - - Google Patents

Info

Publication number
FR2384771B1
FR2384771B1 FR7808317A FR7808317A FR2384771B1 FR 2384771 B1 FR2384771 B1 FR 2384771B1 FR 7808317 A FR7808317 A FR 7808317A FR 7808317 A FR7808317 A FR 7808317A FR 2384771 B1 FR2384771 B1 FR 2384771B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7808317A
Other versions
FR2384771A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2384771A1 publication Critical patent/FR2384771A1/fr
Application granted granted Critical
Publication of FR2384771B1 publication Critical patent/FR2384771B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FR7808317A 1977-03-24 1978-03-22 Derives de quinazoline utiles comme medicament Granted FR2384771A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78093977A 1977-03-24 1977-03-24
US87156478A 1978-01-23 1978-01-23

Publications (2)

Publication Number Publication Date
FR2384771A1 FR2384771A1 (fr) 1978-10-20
FR2384771B1 true FR2384771B1 (fr) 1980-04-04

Family

ID=27119777

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7808317A Granted FR2384771A1 (fr) 1977-03-24 1978-03-22 Derives de quinazoline utiles comme medicament
FR7808316A Granted FR2384770A1 (fr) 1977-03-24 1978-03-22 Nouveaux derives de quinazoline utiles comme medicaments

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7808316A Granted FR2384770A1 (fr) 1977-03-24 1978-03-22 Nouveaux derives de quinazoline utiles comme medicaments

Country Status (23)

Country Link
JP (2) JPS53119897A (fr)
AR (3) AR218060A1 (fr)
AT (2) AT367051B (fr)
AU (2) AU521352B2 (fr)
DE (2) DE2812586A1 (fr)
DK (2) DK128878A (fr)
ES (13) ES468126A1 (fr)
FI (2) FI780918A (fr)
FR (2) FR2384771A1 (fr)
GB (2) GB1601991A (fr)
GR (2) GR73170B (fr)
HU (1) HU180782B (fr)
IE (1) IE46505B1 (fr)
IL (2) IL54326A (fr)
IT (2) IT1093710B (fr)
LU (2) LU79293A1 (fr)
MC (2) MC1185A1 (fr)
NL (2) NL7803112A (fr)
NO (2) NO781051L (fr)
NZ (2) NZ186759A (fr)
PH (2) PH14130A (fr)
PT (2) PT67820A (fr)
SE (2) SE7803418L (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425A1 (de) 1975-12-19 1977-06-30 Boehringer Sohn Ingelheim Chinazolonderivate
DE2845766A1 (de) * 1978-10-18 1980-04-30 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES511866A0 (es) * 1982-04-30 1983-06-01 Lafarquim "procedimiento de obtencion de 2-isopropil pirido (2-1-b) quinazolinas y sus sales no toxicas con actividad antianafilactica".
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (de) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim Neue heterocyclische verbindungen, ihre herstellung und verwendung
JPS62238264A (ja) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk 2−ハロ−5−アセチルピリジン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
IT1093710B (it) 1985-07-26
IL54326A0 (en) 1978-06-15
SE7803418L (sv) 1978-09-25
IL54328A0 (en) 1978-06-15
IE780582L (en) 1978-09-24
PT67821B (en) 1980-03-04
NZ186760A (en) 1981-03-16
DE2812586A1 (de) 1978-09-28
FI780917A (fi) 1978-09-25
AR218480A1 (es) 1980-06-13
ES478331A1 (es) 1979-11-16
ES478328A1 (es) 1979-11-01
ES478326A1 (es) 1979-11-01
AU521352B2 (en) 1982-04-01
ES478330A1 (es) 1979-11-01
GR72948B (fr) 1984-01-17
ES478329A1 (es) 1979-11-01
AR218060A1 (es) 1980-05-15
DE2812585A1 (de) 1978-09-28
ATA210478A (de) 1981-10-15
PT67820A (en) 1978-04-01
NL7803122A (nl) 1978-09-26
DK128878A (da) 1978-09-25
ES468127A1 (es) 1979-09-16
IE46505B1 (en) 1983-06-29
FI780918A (fi) 1978-09-25
AU3447578A (en) 1979-09-27
GB1601991A (en) 1981-11-04
LU79293A1 (de) 1979-05-25
DK132778A (da) 1978-09-25
ES478332A1 (es) 1979-11-16
IT7821655A0 (it) 1978-03-24
LU79290A1 (de) 1979-05-25
NZ186759A (en) 1981-03-16
FR2384770A1 (fr) 1978-10-20
IL54328A (en) 1982-03-31
FR2384770B1 (fr) 1980-10-24
AR225415A1 (es) 1982-03-31
PH14130A (en) 1981-02-26
IT7821578A0 (it) 1978-03-23
AT367050B (de) 1982-05-25
ES478333A1 (es) 1979-11-16
HU180782B (en) 1983-04-29
ES478324A1 (es) 1979-11-01
GR73170B (fr) 1983-02-14
AU3447478A (en) 1979-09-27
PH13915A (en) 1980-11-04
PT67821A (en) 1978-04-01
ATA210278A (de) 1981-10-15
NO781053L (no) 1978-09-26
NO781051L (no) 1978-09-26
GB1601371A (en) 1981-10-28
ES478323A1 (es) 1979-11-01
JPS53119897A (en) 1978-10-19
ES468126A1 (es) 1979-09-01
ES478325A1 (es) 1979-11-01
AU521096B2 (en) 1982-03-18
FR2384771A1 (fr) 1978-10-20
MC1186A1 (fr) 1978-12-22
NL7803112A (nl) 1978-09-26
AT367051B (de) 1982-05-25
SE7803419L (sv) 1978-09-25
ES478327A1 (es) 1979-11-01
IT1095493B (it) 1985-08-10
MC1185A1 (fr) 1978-12-22
IL54326A (en) 1982-04-30
JPS53119896A (en) 1978-10-19

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Legal Events

Date Code Title Description
ST Notification of lapse