IL54328A - Substituted pyrido(2,1-b)quinazoline-11-one derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents

Substituted pyrido(2,1-b)quinazoline-11-one derivatives,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL54328A
IL54328A IL54328A IL5432878A IL54328A IL 54328 A IL54328 A IL 54328A IL 54328 A IL54328 A IL 54328A IL 5432878 A IL5432878 A IL 5432878A IL 54328 A IL54328 A IL 54328A
Authority
IL
Israel
Prior art keywords
quinazoline
derivatives
manufacture
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL54328A
Other languages
English (en)
Other versions
IL54328A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL54328A0 publication Critical patent/IL54328A0/xx
Publication of IL54328A publication Critical patent/IL54328A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL54328A 1977-03-24 1978-03-22 Substituted pyrido(2,1-b)quinazoline-11-one derivatives,their manufacture and pharmaceutical compositions containing them IL54328A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78093977A 1977-03-24 1977-03-24
US87156478A 1978-01-23 1978-01-23

Publications (2)

Publication Number Publication Date
IL54328A0 IL54328A0 (en) 1978-06-15
IL54328A true IL54328A (en) 1982-03-31

Family

ID=27119777

Family Applications (2)

Application Number Title Priority Date Filing Date
IL54326A IL54326A (en) 1977-03-24 1978-03-22 Polysubstituted pyrido(2,1-b)quinazolin-11-one derivatives,their preparation and pharmaceutical compositions containing them
IL54328A IL54328A (en) 1977-03-24 1978-03-22 Substituted pyrido(2,1-b)quinazoline-11-one derivatives,their manufacture and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL54326A IL54326A (en) 1977-03-24 1978-03-22 Polysubstituted pyrido(2,1-b)quinazolin-11-one derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
JP (2) JPS53119897A (xx)
AR (3) AR218480A1 (xx)
AT (2) AT367050B (xx)
AU (2) AU521352B2 (xx)
DE (2) DE2812585A1 (xx)
DK (2) DK128878A (xx)
ES (13) ES468127A1 (xx)
FI (2) FI780918A7 (xx)
FR (2) FR2384770A1 (xx)
GB (2) GB1601371A (xx)
GR (2) GR72948B (xx)
HU (1) HU180782B (xx)
IE (1) IE46505B1 (xx)
IL (2) IL54326A (xx)
IT (2) IT1093710B (xx)
LU (2) LU79290A1 (xx)
MC (2) MC1186A1 (xx)
NL (2) NL7803112A (xx)
NO (2) NO781053L (xx)
NZ (2) NZ186759A (xx)
PH (2) PH14130A (xx)
PT (2) PT67821B (xx)
SE (2) SE7803419L (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557425C2 (de) 1975-12-19 1987-03-19 C.H. Boehringer Sohn, 6507 Ingelheim 11-Oxo-11-H-pyrido[2,1-b]-chinazolin-2-carbonsäure und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
DE2845766A1 (de) * 1978-10-18 1980-04-30 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES511866A0 (es) * 1982-04-30 1983-06-01 Lafarquim "procedimiento de obtencion de 2-isopropil pirido (2-1-b) quinazolinas y sus sales no toxicas con actividad antianafilactica".
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
DE3300477A1 (de) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim Neue heterocyclische verbindungen, ihre herstellung und verwendung
JPS62238264A (ja) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk ２−ハロ−５−アセチルピリジン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation

Also Published As

Publication number Publication date
AU521352B2 (en) 1982-04-01
GB1601991A (en) 1981-11-04
IT1095493B (it) 1985-08-10
ES478332A1 (es) 1979-11-16
ES478324A1 (es) 1979-11-01
GR73170B (xx) 1983-02-14
ES478327A1 (es) 1979-11-01
AU521096B2 (en) 1982-03-18
FR2384770A1 (fr) 1978-10-20
NL7803112A (nl) 1978-09-26
ES468126A1 (es) 1979-09-01
NO781053L (no) 1978-09-26
PT67821A (en) 1978-04-01
AR225415A1 (es) 1982-03-31
FI780917A7 (fi) 1978-09-25
MC1186A1 (fr) 1978-12-22
DE2812585A1 (de) 1978-09-28
IT1093710B (it) 1985-07-26
NO781051L (no) 1978-09-26
LU79293A1 (de) 1979-05-25
ES478330A1 (es) 1979-11-01
DK128878A (da) 1978-09-25
FR2384771B1 (xx) 1980-04-04
ES478328A1 (es) 1979-11-01
NL7803122A (nl) 1978-09-26
FR2384770B1 (xx) 1980-10-24
AT367051B (de) 1982-05-25
GB1601371A (en) 1981-10-28
AU3447578A (en) 1979-09-27
ES478325A1 (es) 1979-11-01
MC1185A1 (fr) 1978-12-22
PH13915A (en) 1980-11-04
IE46505B1 (en) 1983-06-29
IL54326A0 (en) 1978-06-15
LU79290A1 (de) 1979-05-25
JPS53119896A (en) 1978-10-19
ATA210278A (de) 1981-10-15
NZ186759A (en) 1981-03-16
AR218060A1 (es) 1980-05-15
AU3447478A (en) 1979-09-27
NZ186760A (en) 1981-03-16
PT67821B (en) 1980-03-04
IT7821655A0 (it) 1978-03-24
DK132778A (da) 1978-09-25
ES468127A1 (es) 1979-09-16
ES478326A1 (es) 1979-11-01
IE780582L (en) 1978-09-24
ATA210478A (de) 1981-10-15
IL54326A (en) 1982-04-30
IT7821578A0 (it) 1978-03-23
PT67820A (en) 1978-04-01
FI780918A7 (fi) 1978-09-25
ES478329A1 (es) 1979-11-01
GR72948B (xx) 1984-01-17
SE7803419L (sv) 1978-09-25
AT367050B (de) 1982-05-25
ES478331A1 (es) 1979-11-16
JPS53119897A (en) 1978-10-19
SE7803418L (sv) 1978-09-25
HU180782B (en) 1983-04-29
AR218480A1 (es) 1980-06-13
IL54328A0 (en) 1978-06-15
ES478333A1 (es) 1979-11-16
DE2812586A1 (de) 1978-09-28
FR2384771A1 (fr) 1978-10-20
PH14130A (en) 1981-02-26
ES478323A1 (es) 1979-11-01

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