ES478328A1 - Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina.Info
- Publication number
- ES478328A1 ES478328A1 ES478328A ES478328A ES478328A1 ES 478328 A1 ES478328 A1 ES 478328A1 ES 478328 A ES478328 A ES 478328A ES 478328 A ES478328 A ES 478328A ES 478328 A1 ES478328 A1 ES 478328A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxide
- bases
- sodium
- pyridol
- ethanolate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Abstract
Los compuestos forman sales aceptables en farmacia con bases. Ejemplos de estas bases son hidróxidos de metal alcalino, tal como hidróxido sódico, hidróxido potásico y similares; hidróxidos alcalinotérreos, tal como hidróxido cálcico, hidróxido de bario y similares; alcóxido de sodio, tal como etanolato sódico, etanolato potásico y similares; bases orgánicas tal como piperidina, dietilamina, N-metilglucamina y similares.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78093977A | 1977-03-24 | 1977-03-24 | |
| US87156478A | 1978-01-23 | 1978-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES478328A1 true ES478328A1 (es) | 1979-11-01 |
Family
ID=27119777
Family Applications (13)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES468127A Expired ES468127A1 (es) | 1977-03-24 | 1978-03-22 | Un procedimiento para la preparacion de nuevos derivados de pirido (2,1-b) quinazolina |
| ES468126A Expired ES468126A1 (es) | 1977-03-24 | 1978-03-22 | Un procedimiento para la preparacion de nuevos derivados de pirido(2,1b) quinazolina |
| ES478332A Expired ES478332A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478325A Expired ES478325A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478328A Expired ES478328A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478324A Expired ES478324A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478333A Expired ES478333A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478327A Expired ES478327A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478331A Expired ES478331A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478326A Expired ES478326A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478330A Expired ES478330A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478323A Expired ES478323A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478329A Expired ES478329A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES468127A Expired ES468127A1 (es) | 1977-03-24 | 1978-03-22 | Un procedimiento para la preparacion de nuevos derivados de pirido (2,1-b) quinazolina |
| ES468126A Expired ES468126A1 (es) | 1977-03-24 | 1978-03-22 | Un procedimiento para la preparacion de nuevos derivados de pirido(2,1b) quinazolina |
| ES478332A Expired ES478332A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478325A Expired ES478325A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478324A Expired ES478324A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478333A Expired ES478333A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478327A Expired ES478327A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478331A Expired ES478331A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478326A Expired ES478326A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478330A Expired ES478330A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478323A Expired ES478323A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina. |
| ES478329A Expired ES478329A1 (es) | 1977-03-24 | 1979-02-16 | Un procedimiento para la preparacion de nuevos derivados de pirido 2,1-b quinazolina |
Country Status (23)
| Country | Link |
|---|---|
| JP (2) | JPS53119897A (es) |
| AR (3) | AR218480A1 (es) |
| AT (2) | AT367051B (es) |
| AU (2) | AU521352B2 (es) |
| DE (2) | DE2812586A1 (es) |
| DK (2) | DK132778A (es) |
| ES (13) | ES468127A1 (es) |
| FI (2) | FI780917A (es) |
| FR (2) | FR2384770A1 (es) |
| GB (2) | GB1601371A (es) |
| GR (2) | GR72948B (es) |
| HU (1) | HU180782B (es) |
| IE (1) | IE46505B1 (es) |
| IL (2) | IL54328A (es) |
| IT (2) | IT1093710B (es) |
| LU (2) | LU79293A1 (es) |
| MC (2) | MC1186A1 (es) |
| NL (2) | NL7803122A (es) |
| NO (2) | NO781053L (es) |
| NZ (2) | NZ186759A (es) |
| PH (2) | PH14130A (es) |
| PT (2) | PT67821B (es) |
| SE (2) | SE7803419L (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2557425A1 (de) | 1975-12-19 | 1977-06-30 | Boehringer Sohn Ingelheim | Chinazolonderivate |
| DE2845766A1 (de) * | 1978-10-18 | 1980-04-30 | Schering Ag | Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung |
| US4395549A (en) | 1981-10-02 | 1983-07-26 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones |
| ES8306729A1 (es) * | 1982-04-30 | 1983-06-01 | Lafarquim | "procedimiento de obtencion de 2-isopropil pirido (2-1-b) quinazolinas y sus sales no toxicas con actividad antianafilactica". |
| US4551460A (en) * | 1982-05-10 | 1985-11-05 | Hoffmann-La Roche Inc. | Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis |
| DE3300477A1 (de) * | 1983-01-08 | 1984-07-12 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue heterocyclische verbindungen, ihre herstellung und verwendung |
| JPS62238264A (ja) * | 1986-04-04 | 1987-10-19 | Nippon Tokushu Noyaku Seizo Kk | ２−ハロ−５−アセチルピリジン |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4012387A (en) * | 1975-09-18 | 1977-03-15 | Warner-Lambert Company | Benzo-[g]pyrido[2,1-b]quinazolinones |
| US4033961A (en) * | 1975-10-07 | 1977-07-05 | Warner-Lambert Company | Pyrido[2-1-b]quinazolin-ones and their methods of preparation |
-
1978
- 1978-03-22 DK DK132778A patent/DK132778A/da not_active IP Right Cessation
- 1978-03-22 LU LU79293A patent/LU79293A1/de unknown
- 1978-03-22 NO NO781053A patent/NO781053L/no unknown
- 1978-03-22 NO NO781051A patent/NO781051L/no unknown
- 1978-03-22 ES ES468127A patent/ES468127A1/es not_active Expired
- 1978-03-22 IL IL54328A patent/IL54328A/xx unknown
- 1978-03-22 FR FR7808316A patent/FR2384770A1/fr active Granted
- 1978-03-22 NL NL7803122A patent/NL7803122A/xx not_active Application Discontinuation
- 1978-03-22 DK DK128878A patent/DK128878A/da not_active Application Discontinuation
- 1978-03-22 MC MC781292A patent/MC1186A1/xx unknown
- 1978-03-22 NZ NZ186759A patent/NZ186759A/xx unknown
- 1978-03-22 MC MC781291A patent/MC1185A1/xx unknown
- 1978-03-22 PH PH20918A patent/PH14130A/en unknown
- 1978-03-22 HU HU78HO2058A patent/HU180782B/hu unknown
- 1978-03-22 DE DE19782812586 patent/DE2812586A1/de not_active Withdrawn
- 1978-03-22 LU LU79290A patent/LU79290A1/de unknown
- 1978-03-22 FR FR7808317A patent/FR2384771A1/fr active Granted
- 1978-03-22 PH PH20917A patent/PH13915A/en unknown
- 1978-03-22 NL NL7803112A patent/NL7803112A/xx not_active Application Discontinuation
- 1978-03-22 NZ NZ186760A patent/NZ186760A/xx unknown
- 1978-03-22 IL IL54326A patent/IL54326A/xx unknown
- 1978-03-22 DE DE19782812585 patent/DE2812585A1/de not_active Withdrawn
- 1978-03-22 ES ES468126A patent/ES468126A1/es not_active Expired
- 1978-03-23 GR GR55781A patent/GR72948B/el unknown
- 1978-03-23 PT PT67821A patent/PT67821B/pt unknown
- 1978-03-23 FI FI780917A patent/FI780917A/fi not_active Application Discontinuation
- 1978-03-23 GB GB11704/78A patent/GB1601371A/en not_active Expired
- 1978-03-23 PT PT67820A patent/PT67820A/pt unknown
- 1978-03-23 AU AU34474/78A patent/AU521352B2/en not_active Expired
- 1978-03-23 IE IE582/78A patent/IE46505B1/en unknown
- 1978-03-23 IT IT7821578A patent/IT1093710B/it active
- 1978-03-23 AT AT0210478A patent/AT367051B/de not_active IP Right Cessation
- 1978-03-23 FI FI780918A patent/FI780918A/fi not_active Application Discontinuation
- 1978-03-23 GB GB11705/78A patent/GB1601991A/en not_active Expired
- 1978-03-23 AU AU34475/78A patent/AU521096B2/en not_active Expired
- 1978-03-23 GR GR55782A patent/GR73170B/el unknown
- 1978-03-23 SE SE7803419A patent/SE7803419L/xx unknown
- 1978-03-23 AT AT0210278A patent/AT367050B/de not_active IP Right Cessation
- 1978-03-23 SE SE7803418A patent/SE7803418L/xx unknown
- 1978-03-24 IT IT21655/78A patent/IT1095493B/it active
- 1978-03-24 JP JP3400278A patent/JPS53119897A/ja active Pending
- 1978-03-24 JP JP3320578A patent/JPS53119896A/ja active Pending
- 1978-03-27 AR AR271537A patent/AR218480A1/es active
- 1978-03-27 AR AR271538A patent/AR218060A1/es active
-
1979
- 1979-02-16 ES ES478332A patent/ES478332A1/es not_active Expired
- 1979-02-16 ES ES478325A patent/ES478325A1/es not_active Expired
- 1979-02-16 ES ES478328A patent/ES478328A1/es not_active Expired
- 1979-02-16 ES ES478324A patent/ES478324A1/es not_active Expired
- 1979-02-16 ES ES478333A patent/ES478333A1/es not_active Expired
- 1979-02-16 ES ES478327A patent/ES478327A1/es not_active Expired
- 1979-02-16 ES ES478331A patent/ES478331A1/es not_active Expired
- 1979-02-16 ES ES478326A patent/ES478326A1/es not_active Expired
- 1979-02-16 ES ES478330A patent/ES478330A1/es not_active Expired
- 1979-02-16 ES ES478323A patent/ES478323A1/es not_active Expired
- 1979-02-16 ES ES478329A patent/ES478329A1/es not_active Expired
- 1979-05-10 AR AR276467A patent/AR225415A1/es active
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