IE42425B1 - Aryloxy-and arythio-alkanoates having cholesterol-reducing properties - Google Patents

Aryloxy-and arythio-alkanoates having cholesterol-reducing properties

Info

Publication number
IE42425B1
IE42425B1 IE2658/74A IE265874A IE42425B1 IE 42425 B1 IE42425 B1 IE 42425B1 IE 2658/74 A IE2658/74 A IE 2658/74A IE 265874 A IE265874 A IE 265874A IE 42425 B1 IE42425 B1 IE 42425B1
Authority
IE
Ireland
Prior art keywords
group
compound
chlorobenzyl
hydrogen
methyl
Prior art date
Application number
IE2658/74A
Other languages
English (en)
Other versions
IE42425L (en
Original Assignee
Siegfried Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1814573A external-priority patent/CH601169A5/de
Priority claimed from CH1814473A external-priority patent/CH605557A5/de
Priority claimed from CH435574A external-priority patent/CH605642A5/de
Priority claimed from CH1330274A external-priority patent/CH616909A5/de
Priority claimed from CH1533074A external-priority patent/CH617420A5/de
Priority claimed from CH1532974A external-priority patent/CH617417A5/de
Application filed by Siegfried Ag filed Critical Siegfried Ag
Publication of IE42425L publication Critical patent/IE42425L/xx
Publication of IE42425B1 publication Critical patent/IE42425B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Testing Resistance To Weather, Investigating Materials By Mechanical Methods (AREA)
IE2658/74A 1973-12-27 1974-12-23 Aryloxy-and arythio-alkanoates having cholesterol-reducing properties IE42425B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH1814573A CH601169A5 (en) 1973-12-27 1973-12-27 Phenoxy- and phenylthio-alkanes
CH1814473A CH605557A5 (en) 1973-12-27 1973-12-27 Phenoxy- and phenylthio-alkanes
CH435574A CH605642A5 (en) 1974-03-28 1974-03-28 Phenoxy- and phenylthio-alkanes
CH1330274A CH616909A5 (en) 1974-10-03 1974-10-03 Process for the preparation of aromatically substituted olefins
CH1533074A CH617420A5 (en) 1974-11-18 1974-11-18 Process for the preparation of novel pivaloyloxymethyl esters
CH1532974A CH617417A5 (es) 1973-12-27 1974-11-18

Publications (2)

Publication Number Publication Date
IE42425L IE42425L (en) 1975-06-27
IE42425B1 true IE42425B1 (en) 1980-08-13

Family

ID=27543738

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2658/74A IE42425B1 (en) 1973-12-27 1974-12-23 Aryloxy-and arythio-alkanoates having cholesterol-reducing properties

Country Status (11)

Country Link
JP (1) JPS5934695B2 (es)
BE (1) BE823904A (es)
DE (2) DE2463001C2 (es)
DK (1) DK157005C (es)
FR (1) FR2255891B1 (es)
GB (1) GB1497266A (es)
IE (1) IE42425B1 (es)
LU (1) LU71561A1 (es)
NL (1) NL7416412A (es)
SE (1) SE426582B (es)
SU (1) SU612619A3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI773375A (fi) * 1976-11-15 1978-05-16 Siegfried Ag Herbicidiskt verksamt medel och preparat samt foerfarande foer selektiv bekaempning av ograes
US4214095A (en) * 1979-01-25 1980-07-22 Siegfried Aktiengesellschaft Chlorobenzyl phenoxy alkoxylates
FR2481702A1 (fr) * 1980-04-30 1981-11-06 Anvar Phenoxyacetates substitues d'amines cycliques, procede d'obtention, applications a titre de medicaments et compositions pharmaceutiques les contenant
DE3037391A1 (de) * 1980-10-03 1982-05-19 King Consult GmbH, 5000 Köln Ester von 7-hydroxyalkyl-1,3-dimethylxanthinen, verfahren zu ihrer herstellung und ihre verwendung als lipidsenkende mittel
EP0059974B1 (de) * 1981-03-11 1985-07-31 Ludwig Merckle GmbH & Co. chem.-pharm. Fabrik Verfahren zur Herstellung von Phenoxyalkancarbonsäureestern von Hydroxyäthyltheophyllin
JPS59172440A (ja) * 1983-03-23 1984-09-29 Nippon Tokushu Noyaku Seizo Kk 置換フエノキシプロピオン酸エステル及びその中間体、それらの製法並びに除草剤
DE3891219T1 (de) * 1988-01-22 1990-02-01 Kh Nii Endokrinologii I Chimii P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie
DE102011006425A1 (de) 2010-03-31 2011-10-06 Awd.Pharma Gmbh & Co. Kg Pharmazeutische Zubereitung und deren Verwendung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
GB1064252A (en) * 1963-09-19 1967-04-05 Ici Ltd Amides and pharmaceutical compositions containing them
FR1498459A (es) * 1965-07-30 1968-01-08
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
DE2149070C3 (de) * 1971-10-01 1978-03-23 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
GB1422679A (en) * 1972-11-16 1976-01-28 Funai Pharmaceutical Ind Ltd Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same
DE2308826C3 (de) * 1973-02-22 1980-03-27 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkancarbonsäureester von Oxyalkyltheophyllinen, Verfahren zu ihrer Herstellung und Arzneimittel

Also Published As

Publication number Publication date
AU7690274A (en) 1976-07-01
DK157005B (da) 1989-10-30
DE2461069A1 (de) 1975-07-17
SE7416163L (es) 1975-06-30
IE42425L (en) 1975-06-27
DE2463001C2 (es) 1988-11-24
JPS5934695B2 (ja) 1984-08-24
GB1497266A (en) 1978-01-05
JPS50105621A (es) 1975-08-20
LU71561A1 (es) 1975-08-20
DK157005C (da) 1990-03-26
FR2255891B1 (es) 1978-11-10
DE2461069B2 (de) 1980-10-02
SE426582B (sv) 1983-01-31
SU612619A3 (ru) 1978-06-25
DE2461069C3 (de) 1981-07-23
DK670274A (es) 1975-09-08
FR2255891A1 (es) 1975-07-25
NL7416412A (nl) 1975-07-01
BE823904A (fr) 1975-06-27

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