DE3891219T1 - P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie - Google Patents

P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie

Info

Publication number
DE3891219T1
DE3891219T1 DE883891219T DE3891219T DE3891219T1 DE 3891219 T1 DE3891219 T1 DE 3891219T1 DE 883891219 T DE883891219 T DE 883891219T DE 3891219 T DE3891219 T DE 3891219T DE 3891219 T1 DE3891219 T1 DE 3891219T1
Authority
DE
Germany
Prior art keywords
dezyles
chlorphenoxysobutteric
hyperlipidaemia
acid
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE883891219T
Other languages
English (en)
Inventor
Erfinder Wird Nachtraeglich Benannt Der
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH NII ENDOKRINOLOGII I CHIMII
KI MED I
Original Assignee
KH NII ENDOKRINOLOGII I CHIMII
KI MED I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KH NII ENDOKRINOLOGII I CHIMII, KI MED I filed Critical KH NII ENDOKRINOLOGII I CHIMII
Publication of DE3891219T1 publication Critical patent/DE3891219T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE883891219T 1988-01-22 1988-01-22 P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie Withdrawn DE3891219T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SU1988/000019 WO1989006643A1 (en) 1988-01-22 1988-01-22 UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT

Publications (1)

Publication Number Publication Date
DE3891219T1 true DE3891219T1 (de) 1990-02-01

Family

ID=21617183

Family Applications (1)

Application Number Title Priority Date Filing Date
DE883891219T Withdrawn DE3891219T1 (de) 1988-01-22 1988-01-22 P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie

Country Status (6)

Country Link
JP (1) JPH02502998A (de)
DE (1) DE3891219T1 (de)
FR (1) FR2630736B1 (de)
GB (1) GB2221681A (de)
SE (1) SE8903047D0 (de)
WO (1) WO1989006643A1 (de)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717669A (en) * 1968-06-18 1973-02-20 American Home Prod 2-phenoxyalkanoic acid esters
FR2085634A1 (en) * 1970-04-14 1971-12-31 Synthelabo 2-(parachlorophenoxy)-2-methyl propionic esters - hypolipemics and hypocholesterolemics
GB1422679A (en) * 1972-11-16 1976-01-28 Funai Pharmaceutical Ind Ltd Substituted phenoxy-a-methylpropionic acid derivatives and a process for producing the same
NL7416412A (nl) * 1973-12-27 1975-07-01 Siegfried Ag Werkwijze ter bereiding van nieuwe cholesterol- gende verbindingen.
JPS5154918A (en) * 1974-10-08 1976-05-14 Nippon Kayaku Kk Jozaino seizoho
NL184308C (nl) * 1975-07-24 1989-06-16 Takeda Chemical Industries Ltd Werkwijze voor het bereiden van l-ascorbienzuurgranules.
US4326882A (en) * 1978-08-28 1982-04-27 Ppg Industries, Inc. Trichlorophenoxy alkanoic acid free of chlorinated dibenzo-p-dioxins
JPS5559140A (en) * 1978-10-30 1980-05-02 Sankyo Co Ltd 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
JPS5576840A (en) * 1978-12-01 1980-06-10 Kaken Pharmaceut Co Ltd New oxyacetic acid derivative, its preparation and blood- lipid depressor containing it as active principle
SE450381B (sv) * 1979-02-08 1987-06-22 Merz & Co Estrar av nikotinsyra och 2-(p-klorfenoxi)-isosmorsyra till anvendning som lipidsenkande medel
EP0032631A3 (de) * 1980-01-16 1981-11-11 Fbc Limited Unkraut bekämpfende Derivate der Phenoxyalkansäure, ihre Herstellung, sie enthaltende Zusammensetzungen und ihre Anwendung
AT378952B (de) * 1981-12-14 1985-10-25 Arcana Chem Pharm Verfahren zur herstellung von phenoxyisobutters|ureestern
GB2142822B (en) * 1983-06-29 1987-02-11 Alec Stanley Walter Shaw Nicotine lozenges
GB8330407D0 (en) * 1983-11-15 1983-12-21 Sterwin Ag Halocyclopropyl-substituted phenoxyalkanoic acids and esters
FR2598146B1 (fr) * 1986-04-30 1989-01-20 Rech Ind Nouveau procede de preparation de fibrates.

Also Published As

Publication number Publication date
FR2630736B1 (fr) 1990-08-24
JPH02502998A (ja) 1990-09-20
WO1989006643A1 (en) 1989-07-27
SE8903047L (sv) 1989-09-15
GB2221681A (en) 1990-02-14
FR2630736A1 (fr) 1989-11-03
GB8920466D0 (en) 1989-11-01
SE8903047D0 (sv) 1989-09-15

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DE3891219T1 (de) P-chlorphenoxysobuttersaeureundezylester und arzneimittel auf dessen grundlage zur behandlung der hyperlipidaemie
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Legal Events

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8130 Withdrawal