DE68907769D1 - Vorrichtung zum schutz und zur verabreichung von fluessigkeitsempfindlichen arzneimitteln. - Google Patents

Vorrichtung zum schutz und zur verabreichung von fluessigkeitsempfindlichen arzneimitteln.

Info

Publication number
DE68907769D1
DE68907769D1 DE8989302699T DE68907769T DE68907769D1 DE 68907769 D1 DE68907769 D1 DE 68907769D1 DE 8989302699 T DE8989302699 T DE 8989302699T DE 68907769 T DE68907769 T DE 68907769T DE 68907769 D1 DE68907769 D1 DE 68907769D1
Authority
DE
Germany
Prior art keywords
administration
protection
liquid
medicinal products
sensitive medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989302699T
Other languages
English (en)
Other versions
DE68907769T2 (de
Inventor
James B Eckenhoff
Judy A Magruder
Richard Cortese
John R Peery
Jeremy C Wright
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE68907769D1 publication Critical patent/DE68907769D1/de
Application granted granted Critical
Publication of DE68907769T2 publication Critical patent/DE68907769T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
DE89302699T 1988-03-25 1989-03-20 Vorrichtung zum schutz und zur verabreichung von fluessigkeitsempfindlichen arzneimitteln. Expired - Lifetime DE68907769T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/173,209 US4855141A (en) 1988-03-25 1988-03-25 Device comprising means for protecting and dispensing fluid sensitive medicament

Publications (2)

Publication Number Publication Date
DE68907769D1 true DE68907769D1 (de) 1993-09-02
DE68907769T2 DE68907769T2 (de) 1993-11-04

Family

ID=22630995

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89302699T Expired - Lifetime DE68907769T2 (de) 1988-03-25 1989-03-20 Vorrichtung zum schutz und zur verabreichung von fluessigkeitsempfindlichen arzneimitteln.

Country Status (17)

Country Link
US (1) US4855141A (de)
EP (1) EP0337613B1 (de)
JP (1) JPH01299568A (de)
AR (1) AR240398A1 (de)
AT (1) ATE91912T1 (de)
AU (1) AU621588B2 (de)
BR (1) BR8901408A (de)
CA (1) CA1337038C (de)
DE (1) DE68907769T2 (de)
DK (1) DK139589A (de)
ES (1) ES2041988T3 (de)
FI (1) FI891430A (de)
IE (1) IE61335B1 (de)
NO (1) NO177887C (de)
NZ (1) NZ227926A (de)
PT (1) PT90074B (de)
ZA (1) ZA891892B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4996060A (en) * 1988-03-25 1991-02-26 Alza Corporation Device comprising liner for protecting fluid sensitive medicament
US5135523A (en) * 1988-12-13 1992-08-04 Alza Corporation Delivery system for administering agent to ruminants and swine
US5174999A (en) * 1988-12-13 1992-12-29 Alza Corporation Delivery system comprising fluid ingress and drug egress
US5110596A (en) * 1988-12-13 1992-05-05 Alza Corporation Delivery system comprising means for delivering agent to livestock
US5059423A (en) * 1988-12-13 1991-10-22 Alza Corporation Delivery system comprising biocompatible beneficial agent formulation
US5057318A (en) * 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US5037420A (en) * 1988-12-13 1991-08-06 Alza Corporation Delivery system comprising two sections for delivering somatotropin
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US5034229A (en) 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
EP0374120A3 (de) * 1988-12-13 1991-07-31 Monsanto Company Zusammensetzung mit kontrollierter Wirkstoffabgabe von Polypeptiden
US5112614A (en) * 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
US5156851A (en) * 1990-06-20 1992-10-20 Monsanto Company Coated veterinary implants
US5234693A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5234694A (en) * 1990-07-11 1993-08-10 Alza Corporation Method for increasing feed efficiency in animals
US5180591A (en) * 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
US5238687A (en) * 1990-07-11 1993-08-24 Alza Corporation Delivery device with a protective sleeve
US5713888A (en) * 1990-10-31 1998-02-03 Baxter International, Inc. Tissue implant systems
JP3508023B2 (ja) * 1990-10-31 2004-03-22 バクスター、インターナショナル、インコーポレイテッド 密接血管化埋め込み材料
US5545223A (en) * 1990-10-31 1996-08-13 Baxter International, Inc. Ported tissue implant systems and methods of using same
PT100221A (pt) * 1991-03-12 1994-05-31 Alza Corp Dispositivo de libertacao de um agente activo eficiente relativamente ao espaco e a estabilidade
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
US5801141A (en) * 1991-06-24 1998-09-01 American Cyanamid Company Implant compositions containing a biologically active protein, peptide or polypeptide
ZA927779B (en) * 1991-10-10 1993-07-05 Alza Corp Osmotic drug delivery devices with hydrophobic wall materials.
US5462741A (en) * 1992-08-06 1995-10-31 Alza Corporation High agent loaded controlled release dispenser
WO1995008355A1 (en) * 1993-09-24 1995-03-30 Baxter International Inc. Methods for enhancing vascularization of implant devices
US6156305A (en) * 1994-07-08 2000-12-05 Baxter International Inc. Implanted tumor cells for the prevention and treatment of cancer
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
AU731358B2 (en) * 1994-10-28 2001-03-29 Alza Corporation Injection-molded dosage form
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
ZA9711731B (en) 1996-12-31 1998-07-01 Monsanto Co Aqueous glycerol formulations of somatotropin
US6994851B1 (en) 1997-07-10 2006-02-07 Mannkind Corporation Method of inducing a CTL response
US6977074B2 (en) 1997-07-10 2005-12-20 Mannkind Corporation Method of inducing a CTL response
US6551613B1 (en) * 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
WO2003024357A2 (en) 2001-09-14 2003-03-27 Martin Francis J Microfabricated nanopore device for sustained release of therapeutic agent
EP2351577A1 (de) * 2004-12-29 2011-08-03 Mannkind Corporation Verfahren zum Auslösen, Beibehalten und Manipulieren von Immunantworten durch gezielte Verabreichung von Modifikationsmitteln der biologischen Reaktion in lymphatische Organe
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
EP1912622A2 (de) * 2005-08-04 2008-04-23 Alza Corporation Osmotische dosierungsformen mit halbdurchlässigen membranen mit polymer-mischungen mit verbesserten eigenschaften

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2779241A (en) * 1954-06-18 1957-01-29 Wellington R Howard Elastic action cannon bore scavenger
US3896819A (en) * 1969-04-01 1975-07-29 Alejandro Zaffaroni IUD having a replenishing drug reservoir
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3865108A (en) * 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4063064A (en) * 1976-02-23 1977-12-13 Coherent Radiation Apparatus for tracking moving workpiece by a laser beam
US4111203A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4203439A (en) * 1976-11-22 1980-05-20 Alza Corporation Osmotic system with volume amplifier for increasing amount of agent delivered therefrom
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4207893A (en) * 1977-08-29 1980-06-17 Alza Corporation Device using hydrophilic polymer for delivering drug to biological environment
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
JPS55133266A (en) * 1979-04-05 1980-10-16 Alza Corp Liquid distributor
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4309996A (en) * 1980-04-28 1982-01-12 Alza Corporation System with microporous releasing diffusor
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
NZ206600A (en) * 1983-05-11 1987-01-23 Alza Corp Osmotic drug delivery device
ES8800043A1 (es) * 1985-08-16 1987-10-16 Alza Corp Un dispositivo distribuidor para descargar una formulacion de agente beneficioso a un entorno de uso

Also Published As

Publication number Publication date
NO177887B (no) 1995-09-04
NO891224D0 (no) 1989-03-21
DK139589D0 (da) 1989-03-21
BR8901408A (pt) 1989-11-07
CA1337038C (en) 1995-09-19
ZA891892B (en) 1989-11-29
US4855141A (en) 1989-08-08
EP0337613A1 (de) 1989-10-18
FI891430A (fi) 1989-09-26
AU3012189A (en) 1989-09-28
PT90074A (pt) 1989-11-10
IE61335B1 (en) 1994-11-02
NO891224L (no) 1989-09-26
EP0337613B1 (de) 1993-07-28
JPH01299568A (ja) 1989-12-04
NZ227926A (en) 1992-03-26
IE890893L (en) 1989-09-25
PT90074B (pt) 1994-03-31
AU621588B2 (en) 1992-03-19
DE68907769T2 (de) 1993-11-04
ATE91912T1 (de) 1993-08-15
FI891430A0 (fi) 1989-03-23
AR240398A1 (es) 1990-04-30
NO177887C (no) 1995-12-13
ES2041988T3 (es) 1993-12-01
DK139589A (da) 1989-09-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee